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Objective:We wanted to explore if FTO genotype interacts with fat intake, or leisure-time physical activity, on fat mass, lean mass and mortality.Subjects and methods:Among 22 799 individuals (44-74 years) in the population-based Malmö diet and cancer cohort that were genotyped for rs9939609 in FTO and had information on dietary intake (from a modified diet history method) and no history of diabet

AIMS/HYPOTHESIS: The T allele of transcription factor 7-like 2 gene variant, TCF7L2 rs7903146, increases the risk of type 2 diabetes by 40-50%. As TCF7L2 rs7903146 has been associated with diminished incretin effect we investigated whether interaction between dietary intake of carbohydrate, fat, protein or fibre and this variant affects the risk of type 2 diabetes. METHODS: A cohort of 24,799

OBJECTIVE: This article, based on the Early Manifest Glaucoma Trial (EMGT), provides prospective natural history data on progression of glaucomatous field defects in 3 of the most common glaucoma types. DESIGN: Cohort of EMGT patients randomized to the untreated control group and followed up to the time of progression, when treatment could be initiated. PARTICIPANTS: We evaluated 118 control patie

Aims Orthostatic hypotension (OH) has been linked to increased mortality and incidence of cardiovascular disease in various risk groups, but determinants and consequences of OH in the general population are poorly studied. Methods and results Prospective data of the Swedish 'Malmö Preventive Project' (n = 33 346, 67.3% men, mean age 45.7 +/- 7.4 years, mean follow-up 22.7 +/- 6.0 years) were analy

Background: Genetic polymorphisms associated with common aetiologically complex diseases have recently been identified through genome-wide association studies. Direct-to-consumer genetic testing for such polymorphisms, with provision of absolute genetic risk estimates, is marketed by several commercial companies. Polymorphisms associated with atrial fibrillation (AF) have shown relatively large r

Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.

Emojikulturen - Emotionalisering och församtaligande av skriftlig medierad kommunikation är författad av Hannah Busch och Emma Olausson, vid Institutionen för kommunikation och medier vid Lunds universitet. Studiens syfte har varit att utmana föreställningen om att förmågan att kommunicera känslor i medierad kommunikation gått förlorat i och med den ökade digitaliseringen, genom att undersöka vad

Denna studie har strävat efter att undersöka hur högerorienterade digitala alternativa nyhetssidor i USA porträtterar politik i sin nyhetsrapportering. För att undersöka detta har studien utfört en kvalitativ gestaltningsanalys av hur två av USA:s största högerorienterade alternativa nyhetssidor, Breitbart News och The Daily Caller, rapporterade om riksrättsprocessen mot Donald Trump inom tidsrameThis study has aimed to investigate how “right-wing” alternative media news websites in the United States frame politics through their news reporting. To determine this, the study has conducted a qualitative framing analysis of how two of the United States’ major right-wing news websites’, Breitbart News and The Daily Caller, reported on the impeachment process against Donald Trump within the time

Controlling growth of a cell How incredible would it be to control growth of cells? One of the most basic mechanisms in life. This knowledge would be especially useful for treating threatening cells such as cancer cells or pathogenic bacteria. It would be lifesaving to understand and determine their growth. Here the focus is on growth of bacteria, particularly those belonging to the genus Strepto

Fire and grazing, a disaster or opportunity? Due to climate change, disturbances such as forest fires are expected to see an increase in frequency in the 21st century. Fires can increase species diversity since it can create habitats for early successional species. At least if it does not happen too often. Imagine living in a house that burns down every year, it would not be a very nice place to

In Lund, a club culture has been evolving among the city's university students, which has had a great importance on the university life. It is not uncommon for students to go out to a nightclub several times a week, particularly to Student Nations clubs. I have therefore chosen to investigate clubculture in Lund university, through participant observation and interviews. I have also decided to

The purpose of this paper is to speak on the similarities and differences between the Traverso and the Boehm-flute, specifically on interpretation and focusing on the embouchure, sound colour, and tuning systems. The written format of this study allowed me to express better and be more specific on the information selected to be more concise and beneficial to what I intended from this research. As

Finding my inner Nimrud - my life as an ADHD musician This is a master's thesis on the relationship between ADHD and music, not in medicine. With this work, I aim to highlight the advantages, hyper-abilities and great creative potential that ADHD give me as a musician. I got the ADHD diagnosis after 4 years of study at the Academy of Music. Before that I lived 30 years with only the disadvanta

Context:The cardiac natriuretic peptides are involved in blood pressure regulation, and large cross-sectional studies have shown lower plasma levels of N-terminal pro-natriuretic peptide levels [N-terminal atrial natriuretic peptide (N-ANP) and N-terminal brain natriuretic peptide (N-BNP)] in patients with insulin resistance, obesity, and diabetes.Objective:In this study, we prospectively tested w

The occurrence of AF increases sharply with age. The aim of this study was to explore and compare prevalent co-morbidity and self-estimated health-related quality of life (HRQoL) in subjects with AF versus subjects with sinus rhythm or pacemaker in 85 years old subjects. We analyzed data from a population of 336 eighty-five years old subjects participating in the Elderly in Linkoping Screening Ass

Popular Abstract in Swedish Omkring 16% av alla cancerfall i världen beräknas vara orsakade av infektioner och omkring 5% av dessa orsakas av humant papillomvirus (HPV). HPV har etablerats som orsak till livmoderhalscancer och kondylom (könsvårtor). HPV-typer som förekommer på hud har förknippats med icke-melanom hudcancer såsom skivepitelcancer (SCC) men också ofarliga hudhudförändringar som aktiAround 5% of all cancer cases worldwide are caused by human papillomavirus (HPV) which has been established as the cause of cervical cancer and genital warts (condylomas). Cutaneous HPV types have been weakly associated with non-melanoma skin lesions such as squamous cell carcinoma (SCC) and actinic keratosis (AK). We have analyzed skin and genital lesions for presence of HPV-DNA in order to searc

Popular Abstract in Swedish Befolkningsutvecklingen i Sverige medför att allt fler människor blir äldre. Detta är ett positivt resultat till följd av att befolkningen är vid bättre hälsa. Dock innebär det att fler människor kommer att uppnå en ålder där multisjuklighet (att ha flera kroniska sjukdomar samtidigt), oförmåga att klara sig själv och kognitiv svikt är vanligt förekommande. Detta kommerBackground: People aged over 80 years is the most rapidly growing segment of the population in Sweden. This group is susceptible to multimorbidity, disability and cognitive impairment. Managing these issues will be essential in order to obtain a sustainable healthcare system in the near future. Aim: To determine if increased acknowledgement of cognitive impairment could improve healthcare for el

OBJECTIVE: To investigate the determinants and consequences of orthostatic hypotension in the middle-aged segment of the general population. METHODS: A population of 5722 men aged 52.6 +/- 3.6 years, previously included in the Malmö Preventive Project (n = 22 444 men), was re-screened after 5.6 +/- 1.0 years and thereafter followed up over a period of 19.6 +/- 5.3 years. RESULTS: At re-screening,

In conventional design of pile foundations, all loads are taken by the piles, i.e. the contact pressure between the raft and the soil is neglected. In the last decades geotechnical engineers have started to take this pressure into account in design of pile foundation. Such a foundation, where the raft and the piles interact to transfer the loads to the ground, is in this dissertation called piled