Filetype
The expression of the mRNAs of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT3) and the neurotrophin receptor, TrkB, was studied in the rat hippocampus by in situ hybridization following normothermic (37°C) and protective hypothermic (33°C) transient cerebral ischemia of 15 min duration. In the resistant dentate gyms, normothermic ischemia transiently induc
Ocean acidification (OA) describes a change in the ocean's carbonate chemistry. Whereas its chemical processes are largely understood, the biological and socioeconomic consequences particularly in relation to fisheries are less known. Norway is a major fishing nation worldwide and is potentially affected by OA. To improve the understanding of the socioeconomic consequences of OA, we conducted a ri
BACKGROUND: Asthma-like symptoms, methacholine hyperresponsiveness, use of inhaled steroids, airway inflammation, and increased tenascin expression in the reticular basement membrane have been reported in competitive cross-country skiers. OBJECTIVE: To investigate the effect of inhaled budesonide, 400 mug twice daily, on indices of airway inflammation in 'ski asthma', defined as asthma-like sympto
Background: The Multiple Outcomes of Raloxifene Evaluation (MORE) study showed that treatment with raloxifene reduces the risk of vertebral fracture and breast cancer in postmenopausal women with osteoporosis. Objective: Based on the MORE study the aim of the present study was to assess the cost effectiveness of raloxifene (compared with no treatment) for the treatment of osteoporosis in postmenop
Breast cancer is one of the most common cancer forms affecting many women. The disease nevertheless has widely varying behavior and therefore patient outcome, and an important undertaking is to define and understand the molecular mechanisms behind these actions. Defects in the G1/S transition in the cell cycle affect both tumor proliferation and the fidelity of check points responsible for chromos
The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. At low concentrations of denaturant the transition state occurs early in the folding reaction, whereas at high denaturant concentration it moves close to the nati
SynopsisReactivity trends of thioethers toward square-planar complexes can be generally interpreted by use of an equation of the form: log k = γ + α∑σ* + βθ, where k denotes second-order rate constants, ∑σ* the sum of Taft constants for the thioether substituents, and θ the thioether cone angles. γ represents an intrinsic parameter for each substrate complex, while α is an electronic and β a sterSynopsisReactivity trends of thioethers toward square-planar complexes can be generally interpreted by use of an equation of the form: log k = γ + α∑σ* + βθ, where k denotes second-order rate constants, ∑σ* the sum of Taft constants for the thioether substituents, and θ the thioether cone angles. γ represents an intrinsic parameter for each substrate complex, while α is an electronic and β a ster
The group of cetrarioid lichens with globose ascospores includes 37 species from eight genera. Phylogenetic analysis, using program PAUP 3.1.1, was carried out on two different data sets – morphological (incl. anatomical and chemical) and molecular characters (ITS1, 5.8S, and ITS2 rDNA sequences) – to verify the correspondence of current taxonomy to the probable evolution of the taxa involved. TheThe group of cetrarioid lichens with globose ascospores includes 37 species from eight genera. Phylogenetic analysis, using program PAUP 3.1.1, was carried out on two different data sets – morphological (incl. anatomical and chemical) and molecular characters (ITS1, 5.8S, and ITS2 rDNA sequences) – to verify the correspondence of current taxonomy to the probable evolution of the taxa involved. The
Eutrophication is one of the most serious global threats to coastal areas. One effect of eutrophication is seasonal macroalgal blooms. As a consequence, large amounts of beach-cast algae are today reported from coastal areas worldwide. In this study, we analyze nonmarket benefits by capturing local residents' Willingness To Pay (WTP) for an environmental program to regularly remove and utilize bea
Background. Trust is a complex concept, difficult to study, but very important in a patient-family physician relationship. One of the measures used to assess interpersonal trust is a scale developed by Anderson & Dedrick entitled the Trust in Physician Scale (TI PS). Objectives. The aim of the study was to assess the TI PS properties in relation to the age, gender, and health status of primary
We consider how ecosystem services can be incorporated into water infrastructureplanning by studying the projected deepening of the Lower Weser river channel inGermany. We recalculate the project’s benefitcost ratio by integrating the monetaryvalue of changes in different ecosystem services, as follows: (1) the restoration costsof a mitigation measure for a loss in fresh water supply for agricultu
Background and AimsThe island of Gotland in the Baltic Sea has had no contact with surrounding continental areas since the withdrawal of the Weichselian ice sheet at approx. 17 ka BP. Plants present on Gotland must have arrived by long-distance dispersal, so populations are expected to exhibit reduced levels of genetic diversity compared with populations on surrounding mainlands. However, orchids
AIMS: To evaluate the effect of adding insulin to sulphonylurea (SU) and the effect of SU withdrawal on glycaemic control in Type 2 diabetic patients who failed on treatment with SU alone.METHOD: One hundred and seventy-five patients were included in a placebo-controlled multicentre study. During phase I (4 months), premixed insulin was added to glibenclamide therapy; during phase II (1-4 months,
Comparing complication rates between centres is difficult due to the lack of unanimous criteria regarding what adverse events should be defined as complications and how these events should be compiled. This study analysed all adverse events in a cohort of craniofacial (CF) operations over a 10-year period and applied three different scales (Clavien-Dindo, Leeds and Oxford) for systematic compariso
