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Enzyme formulation development is a tedious process that requires lots of time and resources. By improving parts of the formulation process, the formulation of enzymes could become more efficient and allow for quicker commercialization of enzyme products. The focus of this project has been on solid granular enzyme formulations, aiming to accelerate stability studies, develop enzyme degradation pre
This paper discusses the project in which an algorithm was written to dynamically approach federation orchestration. This builds on and is part of the REINDEER project. In an environment with goods and online agents, and in this specific case, Contact Service Points (CSPs) and User Equipments (UEs), where the agents have different applications and make unpredictable changes such as moving around a
The details of galaxy formation are still an unsolved problem in astrophysics. Even though significant progress has been made in simulations and observations, it remains an unsolved issue to describe the complexity it yields. One of the reasons for this is the vast dynamical range in space and time. The smallest scales, where star formation occurs, are connected to the larger scale structure of th
The self-diffusion coefficients of D2O (i.e., heavy water or 2H2O) in eight n-alkanes at 298 K were investigated using 2H NMR diffusometry. D tended to decrease in the n-alkanes with increasing carbon number and be inversely proportional to the n-alkane viscosity to a fractional power. The hydrodynamic radius of D2O in the n-alkanes, calculated from Stokes-Einstein-Sutherland equation with stick b
This chapter is a commentary on the book as a whole. Based on the overall PeTS project, the empirical findings from the four educational settings and the conceptual portions of the book, this chapter focuses on three specific aspects of peer group mentoring: the move from teaching as a private matter to teaching as a collegial responsibility, the relationship between collegiality and peer group me
ABSTRACT In high-risk pregnancies the chronic hypoxemic fetus redistributes its circulation to maintain the blood supply to the vital organs: brain, heart and adrenals. The aims of the studies included in this thesis were: 1) to establish reference curves for fetal cerebral venous blood velocity in normal pregnancies; 2) to determine in high-risk pregnancies the frequency of abnormal Doppler in
The purpose of the paper is to provide more knowledge on how to estimate disruption risk exposure in the supply chain by developing a conceptual estimation model. The purpose is also to shortly illustrate and discuss by help of a case the possibilities to adapt this theoretical model for use in everyday practice.
The developed model, which links disruption risk to disruption source, covers all
The global epidemic of Alzheimer disease (AD) is worsening, and no approved treatment can revert or arrest progression of this disease. AD pathology is characterized by the accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the brain. Genetic data, as well as autopsy and neuroimaging studies in patients with AD, indicate that Aβ plaque deposition precedes cortical tau pathol
This article explores relevant laws and doctrines of patent infringement in Europe with a special emphasis on 3D printing (3DP) technologies. Considering the difficulties that patent owners might face in pursuing direct patent infringement actions in the rapidly evolving era of 3DP, we suggest that patent owners will most likely direct their efforts towards indirect patent infringement strategies.
Purpose: To meet the rising global needs, the humanitarian community has signed off on making a strategic change toward more localisation, which commonly refers to the empowerment of national and local actors in humanitarian assistance. However, to this date, actual initiatives for localisation are rare. To enhance understanding of the phenomenon, the authors explore localisation of logistics prep
Farmers know much more than we think, and they are keen to improve their knowledge in order to improve their farms and increase their income. On the other hand, decision-makers, organizations, and researchers are increasing their use of citizen volunteers to strengthen their outcomes, enhance project implementation, and approach ecosystem sustainability. This paper assesses the role of citizen sci
This thesis presents studies of three different Quark-Gluon Plasma estimators in proton-proton collisions using what is currently believed to be quark-gluon plasma observables; radial flow, elliptic flow and strangeness enhancement. The three tested estimators were Transverse Spherocity, an altered version of Transverse Spherocity where all p_T was put to one, and a newly developed estimator calle
BACKGROUND AND PURPOSE: It is unclear whether stroke in patients with spontaneous dissection of the cervical internal carotid artery (ICAD) is due to thromboembolism or impaired hemodynamics. This study investigated the mechanism of stroke in ICAD by examining brain imaging and cerebrovascular findings of such patients. METHODS: We retrospectively evaluated the prospectively collected brain CT, MR
An experimental model is presented that allows qualitative as well as quantitative studies of the soft tissue response to implant materials used in reconstructive surgery. Plugs of non-alloyed titanium and polymers (Teflon, Delrin) were inserted into the abdominal wall of rats, with a portion of the plug penetrating through the peritoneum into the abdominal cavity. The tissue reaction was evaluate
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The dynamics of visible-to-ultraviolet upconversion in YAlO3: 1% Er3+ crystal has been investigated using the time-resolved laser spectroscopy when the sample was excited into the S-4(3/2) multiplets. It is found that the upconverted luminescence is produced by energy-transfer upconversion or by excited-state absorption depending on the excitation wavelength. The dependence of upconverted luminesc
A hidden Markov regime is a Markov process that governs the time or space dependent distributions of an observed stochastic process. Recursive algorithms can be used to estimate parameters in mixed distributions governed by a Markov regime. Here we derive a recursive algorithm for estimation of parameters in a Markov-modulated Poisson process also called a Cox point process. By this we mean a doub
The portal appearance of enteral alpha-ketoglutarate (AKG) and the effect of enteral or parenteral AKG on portal net appearance of glucose, short-chain fatty acids, alanine, aspartate, glutamate, glutamine, proline and insulin were investigated in three growing pigs. During the experimental samplings the pigs were fed hourly with a standard feed mix with 5% glucose (control), 5% AKG (enteral) or n
The intracellular signal cascade transducing muscarinic-receptor-stimulation to gene expression was investigated in human neuroblastoma SH-SY5Y cells. Naive and ethanol-exposed SH-SU5Y cells were stimulated with carbachol (CCh) and inositol 1,4-5-trisphosphate (IP3), 1,2-diacylglycerol (DAG), and c-fos mRNA levels were analyzed using a radioreceptor assay (IP3) thin-layer chromatography (DAG) and
