Filetype
Cigarette smoke exposure is well known to cause cardiovascular and airway diseases, both of which are leading causes of death and disability in the world. However, the molecular mechanisms that link cigarette smoke to cardiovascular and airway diseases are not fully understood. Vascular and airway hyper-reactivity plays an important role in the pathogenesis of cardiovascular and airway diseases. R
Abstract This study attempts to understand what problem Isa 53 addresses and seeks to answer. The question is asked as an historical question and it is argued that Isa 53 address a specific historical problem, arising out of the conflicts created after the return of those who had gone into exile. At the end of the exile, there was hope that the deported people would return to the land, that the l
Dual process models of recognition memory assume that memory retrieval can be based on two distinct processes: an assessment of a context-free feeling of familiarity or on the reinstatement of specific context attributes that have been bound together to form a representation of the study episode during encoding (recollection). Recent neurophysiological evidence suggests that familiarity and recoll
The production of health economic evaluations of pharmaceuticals is a global, multibillion dollar industry. Despite this fact, little is known about what happens after a health economic evaluation has been produced. Will it be used at all, and if so, how? Who uses economic evaluations and for what purposes? Are there differences in the use patterns between decision makers at macro, meso and micro
Abstract in UndeterminedBackground The role of allergy in the aetiopathogenesis of chronic rhinosinusitis (CRS) remains controversial. For example, in some cases with sinus fungal infections allergy can be demonstrated by standard tests. In other cases, such signs can be absent despite elevated levels of IgE-positive cells in sinus tissue and the presence of IgE and eosinophils in the sinus mucous
PURPOSE: To assess the impact of age on outcome and to analyze the projected years of life lost in patients with multiple myeloma. PATIENTS AND METHODS: Ten thousand five hundred forty-nine patients were evaluated; 6,996 patients were treated with conventional chemotherapy, and 3,553 patients were treated with high-dose therapy with autologous stem-cell transplantation. RESULTS: Mean observed and
In a recent article Wolff et al. (2009) [1] present highly interesting results bearing on how timing of therapeutic hypothermia might affect outcome. However, some of their analyses are unadjusted for heterogeneities in the patient population, while others indicate a statistical model break-down. Moreover, the time from cardiac arrest to return of spontaneous circulation is recorded but not includ
Abstract Objective: A systematic review and meta-analysis was conducted to determine the efficacy and tolerability of tacrolimus ointment for the treatment of atopic dermatitis (AD) compared with topical corticosteroids. Methods: Electronic searches were performed in Medline, Embase and the Cochrane Library, as well as relevant conference proceedings. Two researchers independently selected trials
Introduction: Intense pulsed light (IPL) treatment is well known for, for example, photo rejuvenation, where higher cut-off filters are used. The longer wavelengths penetrate deeper in the dermis leading to damage of the collagen and stimulation of new collagen formation, which lead to more soft and elastic skin. Microstomia in systemic sclerosis is the end result of excessive collagen deposition,
Lifetimes in the 3d(10)np(2)P sequence in neutral copper were measured by time-resolved laser spectroscopy. Excitation from the ground state was performed with pulsed laser radiation in the; vuv spectral region, generated by resonant sum-difference four-wave mixing in krypton gas. The lifetimes were evaluated from recorded optical transients. For the np(2)P(J) states we find the following: tau(n =
Objective: To investigate the development of hand involvement and activities of daily life (ADL) in early systemic sclerosis (SSc), and to examine the usefulness of the Hand Mobility in Scleroderma (HAMIS) test in a longitudinal study. Methods: Forty-three patients with disease duration no longer than 3 years and at least 4 years of follow-up formed the study group. Based on skin involvement, 31 p
OBJECTIVE: Children who undergo surgery for complex congenital cardiac disease are reported to be at increased thrombotic risk. Our aim was to evaluate long-term changes in the haemostatic system after surgery, to compare markers of activated coagulation in children having surgery with those in a healthy control population, and to relate them to adverse clinical outcome.Patients and methodsWe stud
This paper extends earlier works on three-dimensional scattering from a finite obstacle in a stratified halfspace, treated by means of the T-matrix method. In this paper we consider a general source configuration above the ground, that excites the subsurface medium and its inhomogeneity. Explicit expressions are given for the magnetic dipole, the circular, and rectangular antenna loops. Numerical
PURPOSE:: To investigate retinal function and structure after recent-onset rhegmatogenous retinal detachment in relation to type of surgery. METHODS:: Thirteen consecutive patients with rhegmatogenous retinal detachment of <7 days' duration underwent vitrectomy surgery. Optical coherence tomography, full-field electroretinography (ERG), and multifocal ERG were performed preoperatively and 6 months
Genomic locus at chromosome 9p21 that contains the CDKN2A and CDKN2B tumor suppressor genes is inactivated through mutations, deletions and promoter methylation in multiple human cancers. Additionally, the locus encodes an anti-sense RNA (ANRIL). Both hemizygous and homozygous deletions at the locus targeting multiple genes are fairly common in different cancers. We in this study investigated brea
