Search results

Our understanding of celiac disease and how it develops has evolved significantly over the last half century. Although traditionally viewed as a pediatric illness characterized by malabsorption, it is now better seen as an immune illness with systemic manifestations affecting all ages. Population studies reveal this global disease is common and, in many countries, increasing in prevalence. These s

BACKGROUND/AIM: Cervical cancer is associated with poorer diagnosis among the elderly and pap-smear screening has a lower sensitivity. Self-sampling for detection of high-risk human papillomavirus (hr-HPV) may be an alternative screening method. The aim of this study was to analyze the response rate to vaginal HPV self-sampling and the HPV mRNA prevalence among women 69-70 years. MATERIALS AND MET

Innovation within companies is generated by a combination of different types of knowledge from external and geographically dispersed sources. Although the geographical dimension of collaboration has previously been investigated, studies have not distinguished between different types of knowledge involved in collaboration. This article analyses how the number of collaborations between pharmaceutica

Anti-CD20 monoclonal antibodies (mAbs) rituximab and ofatumumab are potent activators of the classical complement pathway, and have been approved for the treatment of B-cell malignancies. However, complement exhaustion and overexpression of complement inhibitors by cancer cells diminish their therapeutic potential. The strategies of targeting membrane complement inhibitors by function-blocking ant

Adenosine A(1) and A(2A) receptors are neuromodulatory systems that can control mnemonic behavior, which is modified by diabetes. Since the density of these adenosine receptors can change upon chronic noxious brain conditions, we now tested if the density of A(1) and A(2A) receptors was modified in the hippocampus of streptozotocin-induced diabetic rats. The binding density of the selective A(1) r

Can wealth shocks have intergenerational health consequences? We use the partial compensation slaveholders received after the 1834 slave emancipation in the British Cape Colony to measure the intergenerational effects of a wealth loss on longevity. Because the share of partial compensation received was uncorrelated to wealth, we can interpret the results as having a causal influence. We find that

The high-pressure homogenizer (HPH) is, together with the rotor–stator mixer (RSM), the standard equipment for emulsification in many fields of chemical processing. Both give rise to intense turbulence which, in turn, gives rise to drop breakup. Previous investigations focus on average turbulent disruptive stress. However, turbulence is a stochastic phenomenon and drop breakup will be characterize

Carbon storage dynamics in vegetation and soil are determined by the balance of carbon influx and turnover. Estimates of these opposing fluxes differ markedly among different empirical datasets and models leading to uncertainty and divergent trends. To trace the origin of such discrepancies through time and across major biomes and climatic regions, we used a model-data fusion framework. The framew

Previous studies reported conflicting results regarding association of insulin receptor substrate 1 (IRS1) gene variation with type 2 diabetes (T2D) and insulin resistance (IR) in different ethnic groups. We examined the association of rs7578326, rs2943641, and rs4675095 in the IRS1 gene with T2D and related traits in a population from Bosn

Humor is essential to social life, but it is often overlooked in the study of crime and other social problems. We introduce and make use of humor theory, emphasizing the theories of superiority and relief. Based on interviews with incarcerated men, we demonstrate how humor is used to criticize authorities, for self-aggrandizement, and to alleviate the pain of tragic experiences. Funny remarks and

Indoor localization and navigation is a much researched and difficult problem. The best solutions, usually use expensive specialized equipment and/or prior calibration of some form. To the average person with smart or Internet-Of-Things devices, these solutions are not feasible, particularly in large scales. With hardware advancements making Ultra-Wideband devices more accurate and low powered, th

After the WWI Battle of Jutland in 1916, hundreds of dead British and German marines drifted ashore on the beaches of the region of Bohuslän in western Sweden. They were buried in local cemeteries, until the remains of most of the soldiers were reburied in Gothenburg in the 1960s. The chapter focuses on two local Bohuslän memory cultures in relation to the sailors and their graves. It seeks to ide

Objective: To evaluate the Patient Participation in Rehabilitation Questionnaire (PPRQ) according to Rasch measurement theory. Method: Five hundred twenty-two post-discharge patients from a neurological rehabilitation unit were included. The PPRQ questionnaire comprises 20 items rated by a cohort of 522 patients about their experiences of participating in rehabilitation. The measurement properties

The Kuh e Dena sedimentary section in Iran developed on the southwestern margin of the Neotethys Ocean. The fossil- and bioturbation-lean Early Triassic section (Late Dienerian to Early Smithian) is typified by finely laminated calcareous shales that are interbedded with laterally extending carbonate beds, which are mostly composed of calyx-shaped carbonate crystal fans. The calyxes consist of fib

The performance of identification algorithms (“taggers”) for hadronically decaying top quarks and W bosons in pp collisions at s = 13 TeV recorded by the ATLAS experiment at the Large Hadron Collider is presented. A set of techniques based on jet shape observables are studied to determine a set of optimal cut-based taggers for use in physics analyses. The studies are extended to assess the utility