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The aim of this study was to evaluate the changes caused by chronic diabetes in the rat ventral prostate and to establish a correlation between diabetes and the development of prostatic lesions. Male rats received alloxan (42 mg/kg b.w.) to induce diabetes. Ninety days after diabetes diagnosis, animals were sacrificed and the ventral prostate was removed and prepared for general and immunohistoche
We have studied double Auger decay after C 1s→2 photoexcitation in gas phase carbon monoxide. Two distinct processes, namely direct double Auger decay and cascade double Auger decay, are identified and studied in detail using multiple coincidence techniques. Cascade Auger decay is shown to be the overall dominant process. Decay channels involving the dissociation of the molecule followed by autoio
Mast cells are strategically localized along the microvasculature in tissues in close contact with the external environment, such as the skin, lung and intestines. By releasing a multi-faceted spectrum of proinflammatory mediators, such as cytokines and chemokines, mast cells have the capacity to coordinate trafficking of leukocytes. Mast cells play a pathophysiological role in numerous inflammato
A participatory methodology, based on dialogues between stakeholders and experts has been developed and tested in the drainage area to Kaggebo Bay in the Baltic Sea. This study is focused on the EU Water Framework Directive, with emphasis on reduction of eutrophication. The drainage area is included in the WFD administrative area of the Motala Strom River basin. A similar approach is now applied i
Objectives Cervical cancer is one of the most common forms of cancer among women. Cytological screening and follow-up are potentially effective procedures for preventing the development of – and mortality from – cervical cancer. The purpose of this study was to investigate the screening history of women diagnosed with cervical cancer with the aim of improving the screening programme. Study design
One interpretation of the model considered in this paper is a single-echelon inventory system consisting of a number of local warehouses, which normally replenish from an outside supplier. In case of a stockout at a warehouse an emergency lateral transshipment from another warehouse may be possible. However, such transshipments are only allowed in one direction, i.e., the flow structure is unidire
CD40 is a member of the tumor necrosis factor receptor super-family and has been suggested to play a role in the metabolism of beta-amyloid (Abeta) in Alzheimer's disease (AD). However, the role of CD40-signalling in incipient AD has not yet been studied. We investigated the plasma levels of soluble CD40 (sCD40) and the soluble CD40 ligand (sCD40L) at baseline in 136 subjects with mild cognitive i
We present a new implementation of the time-resolved fluorescence anisotropy technique for the analysis of carbon nanoparticles directly in a Bunsen-type propane flame. By exploiting femtosecond laser excitation, UV-visible laser-induced fluorescence and time resolution of the experimental set-up, small soot nanoparticles have been identified within the flame. From the measurement of the decay tim
The fission probability and the angular distribution of the associated fission fragments have been measured for the U-235(d,pf)U-236 reaction slightly above the top of the inner fission barrier with the aim of disclosing new hyperdeformed states lying in the third minimum of the fission potential. The results are analyzed together with the data obtained from the literature for U-234. The experimen
The development of science parks constitutes an interesting example of policy to enhance the technology-based development of a region. These parks, it is argued, contribute to fostering technological innovation and transfer and stimulating the growth of high-level economic activities. This article examines the role that science parks play in the promotion of regional development with particular re
In this paper, we study the mechanical degradation and changes in conformation of a branched ultrahigh molar mass biomacromolecule, hydrophobically modified starch, as caused by high-pressure homogenization. The characterization was performed with asymmetrical flow field-flow fractionation (AsFlFFF) with multiangle light scattering (MALS) and refractive index detection. The starch which had been c
The authors propose that the enzyme hormone-sensitive lipase (HSL), which is the rate-limiting enzyme for hydrolysis of triacylglycerol in adipocytes, also regulates the intramyocellular triacylglycerol mobilization and is controlled by mechanisms similar to those regulating glycogen phosphorylase. From an exercise perspective, it is fascinating that the primary enzymatic setting allows simultaneo
We search for signatures of past accretion events in the Milky Way in the recently published catalogue by Nordstrom et al., containing accurate spatial and kinematic information as well as metallicities for 13 240 nearby stars. To optimize our strategy, we use numerical simulations and characterize the properties of the debris from disrupted satellites. We find that stars with a common progenitor
Nerve fibres play an important role in the regulation of gastric emptying. The aims of this study were to clarify the distribution, projections and origin of neuronal type nitric oxide synthase (NOS)-, tyrosine hydroxylase (TH)-, vesicular acetylcholine transporter (VAchT)- and peptide-containing nerve fibres of the rat pyloric sphincter. Extrinsic and local denervations of the sphincter were perf
One of the central questions in theoretical particle physics, since already several decades, has been that of "masses and mixings of the quarks. With the entry of neutrino oscillations into the field, the issue of lepton masses has added a new dimension to the problem. In the literature one finds many models of quark and lepton mass matrices. However, the mass and mixing problems remain unsolved.
Scheelite CdMoO4 and wolframite eCdWO(4):MO (0.04-0.4wt%) single crystals were studied using the time-resolved spectroscopy under UV excitation over a temperature range of 1.85-300K. The threshold energies for the creation of free charge carriers were measured using the method of photostimulated luminescence. The decay kinetics of the main emission in CdMoO4 and the molybdenum-related emission in
The European steady-state Simple Mass Balance (SMB) model and the dynamic soil acidification model SAFE were used to assess the risk of future forest soil acidification in Switzerland. 2010 deposition forecasts on a 150x150 km grid resolution as well as corresponding ecosystem protection levels were obtained from RAINS model runs based on the 1999 Gothenburg Protocol obligations under the UN/ECE L
Time-resolved transmittance was used to extract in vivo optical properties of leaves of green plants experimentally. In time-resolved transmittance measurements an ultrashort light pulse is directed onto the surface of the object and the transmitted light is measured with a time resolution in the range of picoseconds. A table-top terawatt laser was used to generate 200 fs light pulses at 790 nm wi
To study the role of the dispersion of atrial repolarization (DAR) in the genesis of atrial fibrillation (AF), monophasic action potentials (MAP) were recorded simultaneously from a catheter at the high lateral right atrium (HLRA) and a catheter moving around the high, middle and low lateral right atrium (RA) the high, anterior and posterior septal RA and the RA appendage in 15 patients with parox
