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Although spatial resolution in fluorescence microscopy and related fields has advanced to the nanometer scale, time resolution has remained essentially unchanged and is set by the camera system’s imaging time. Yet adequate time resolution is crucial for information acquisition about, for instance, dynamical processes in cells. This acquisition typically proceeds by analyzing biomolecular trajector
Carbon Black (CB), graphene, and nanodiamonds represent three classes of manufactured carbonaceous nanoparticles consisting almost exclusively of insoluble material. Particle-related Reactive Oxygen Species (ROS) have been linked to in vivo and in vitro toxicity and determining particle ROS activity is an efficient way of estimating nanomaterial toxicity and assist in the safe-by-design developmen
Syphilis has re-emerged as a public health threat during the 21st century, and updated knowledge of the epidemic and its drivers is needed to halt this worrying development. We present data on the incidence of syphilis in the south Swedish region Skåne from 2007 to 2022 to determine the burden of disease, changes in risk groups, as well as routes for testing. To get a picture of the burden of syph
When the polar vortex meanders and shifts towards the equator, air masses from the tropics and subtropics can be transported towards the pole in so-called tropical-subtropical streamers. These large-scale structures are areas of low potential vorticity and high pressure, containing dry air with high ozone mixing ratios. The presence of these streamers can also be seen in changes in stratospheric o
This review examines how coordination is infrastructured in digital health ecosystems where technologies, institutions, and practices intersect across organisational and professional boundaries. Drawing on a systematic analysis of the literature, we identify three interdependent infrastructural layers: technological, informational, and institutional, and four recurring processes through which coor
Background: Women who have undergone cervical conization may still experience subsequent pregnancies and delivery. However, it remains unknown whether pregnancy, associated with immune tolerance, might increase the risk of subsequent cervical lesions. This study aims to address this knowledge gap by utilizing the nationwide Swedish registers. Methods: A total of 60,895 women diagnosed with cervica
Groundwater-dependent vegetation (GDV) plays a vital role in maintaining biodiversity and ecosystem services in the Mediterranean biome but is increasingly threatened by climate and land use change. Large-scale GDV mapping in arid regions is critical for effective conservation and water resource management but remains challenging due to limited ground-truth data and the lack of high-resolution rem
INTRODUCTION: There are few recent studies on trends over time in functional outcome and mortality after stroke, with results separately presented for ischaemic stroke (IS) or ICH. We aimed to determine temporal changes in functional outcome and case-fatality 90 days after IS and ICH in Sweden between 2010 and 2019. PATIENTS AND METHODS: We included patients (≥18 years) with first-ever IS or ICH r
Objective: Cystic fibrosis (CF) is a congenital condition caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. CF-related diabetes (CFRD) is a common comorbidity among people with CF (pwCF) and is associated with increased morbidity. Previous in vitro studies have suggested that CFTR dysfunction is involved in the pathogenesis of CFRD. This prospective study aimed to eval
Background: Emerging evidence suggests that COVID-19 may influence obstructive sleep apnea (OSA) pathophysiology by affecting upper airway collapsibility, ventilatory control, and arousal responses, raising the possibility of a bidirectional relationship. This study examined whether individuals with a history of COVID-19 show altered OSA-related physiological traits compared with those without pri
The diffusion of water and the cross relaxation between water and cellulose in a hydrated paper system were followed with the Goldman-Shen and the pulsed-field-gradient stimulated-echo NMR pulse sequences as a function of moisture content. The diffusion coefficient measured along the plane of the paper sheet is very sensitive to the moisture content; more water leads to faster diffusion. The cress
Psychiatric disorders are highly heritable and polygenic, influenced by environmental factors and often comorbid. Large-scale genome-wide association studies (GWASs) through consortium efforts have identified genetic risk loci and revealed the underlying biology of psychiatric disorders and traits. However, over 85% of psychiatric GWAS participants are of European ancestry, limiting the applicabil
BACKGROUND: Hypertension is a significant risk factor for several neurological disorders, including stroke and dementia, yet the molecular mechanisms underlying these risks remain poorly understood. In this study, we investigated temporal proteomic remodeling of the cerebrovasculature in male spontaneously hypertensive rats and normotensive Wistar-Kyoto controls at 30 and 40 weeks of age, represen
Several factors contribute to the use, non-use, or inadequate use of personal protective equipment (PPE) in construction work. This study aimed to analyse correct usage of various PPE, such as helmet, ear protectors, goggles, respiratory mask, gloves, protective clothing, and a safety harness. Correct usage was assessed as guessability, which refers to human perceptions of how to don, adjust, use,
The dependence of f0(980) production on the final-state charged-particle multiplicity is reported for proton–proton (pp) collisions at the centre-of-mass energy, s= 13 TeV. The production of f0(980) is measured with the ALICE detector via the f0(980)?p+p- decay channel in a midrapidity region of |y|
The standard way of representing an epistemic state in formal philosophy is in terms of a set of sentences, corresponding to the agent's beliefs, and an ordering of those sentences, reflecting how well entrenched they are in the agent's epistemic state. We argue that this wide-spread representational view-a view that we identify as a "Quinean dogma" - is incapable of making certain crucial distinc
Popular Abstract in Swedish En enkel beskriving av atomen kan utgå från Bohrs atommodell (som emellertid ej är användbar för en exaktare beskrivning): runt kärnan, som består av positivt laddade protoner och neutrala neutroner, kretsar elektroner. Vilket grundämne det är bestäms av antalet protoner i kärnan. Antalet elektroner för en atom är detsamma som antalet protoner i kärnan. Tillförs atomen Atomic data are needed in many different areas of science and technology. Examples of users are the astronomical community and the lighting industry. In this work, the purpose of the projects has been to produce reliable atomic data needed to solve specific astrophysical problems. Oscillator strengths, which are needed when analysing stellar absorption spectra as well as spectra of emission line o
