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In search for a possible explanation of the phenotypic heterogeneity in selective immunoglobulin (Ig)A deficiency, we studied the IgG2 antibody response to meningococcal polysaccharide A (PSA) in IgA-deficient (IgAd) individuals after vaccination with meningococcal A + C polysaccharide vaccine. Two groups of IgAd individuals, one frequently infected and one clinically apparently healthy, as well a

Infants treated in neonatal intensive care units suffer an increased risk for invasive candidiasis, but the diagnosis is sometimes difficult. D-arabinitol is a metabolite of most pathogenic Candida species. An elevated urine D-arabinitol/L-arabinitol (DA/LA) ratio is a sensitive sign of invasive candidiasis in children with cancer, but the method has not been previously evaluated for newborn infan

A health care reform for senior citizens took effect in 1992 in Sweden. Shortcomings as regards geriatric rehabilitation were identified and, in 1995, governmental grants were assigned to local developmental projects. The aim of this study was to report the staff and administration perspectives in a geriatric rehabilitation developmental process over a 1-year period. In all, 782 staff and 45 admin

Repeated exposures to both microbial and innocuous Ags in vivo have been reported to both eliminate and tolerize T cells after their initial activation and expansion. The remaining tolerant T cells have been shown to suppress the response of naive T cells in vitro. This feature is reminiscent of natural CD4+CD25+ regulatory T cells. However, it is not known whether the regulatory function of in vi

The colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay was standardized for direct detection of rifampin-resistant Mycobacterium tuberculosis in sputum samples. The sensitivity and specificity of the direct MTT assay matched those of the standard indirect susceptibility assay on 7H10 medium, and interpretable results were obtained for 98.5% of the samples within

Anti-proliferative drugs have been used for immunosuppression since the introduction of clinical transplantation. Most transplant centres include azathioprine (Aza) and cyclosporine (CyA) in their standard regimens, despite several controlled studies having failed to confirm the benefit of this combination. Aza is still. the most commonly used anti-proliferative drug, although no major differences

Previous time-use research suggests that it is highly relevant for an occupational therapist to estimate time use and occupational engagement in order to understand some of the determinants of wellbeing for people with schizophrenia. This article describes the development and the testing of the psychometric properties of an instrument, Profiles of Occupational Engagement in people with Schizophren

Apparent standard Gibbs energy, enthalpy, entropy, and heat capacity data of the interactions of alpha-cyclodextrin (alphaCD) to some n-carboxylates H(CH2)(n)COO- (n = 4 - 6), are determined by isothermal titration microcalorimetry at different temperatures in phosphate buffer, pH 9.0, assuming a 1 : 1 model in dilute solution. Modelling of contributions of the thermodynamic properties of the solu

Popular Abstract in Swedish Antalet fallolyckor och frakturer ökar ibland den äldre befolkningen och detta innebär en ökande social och ekonomisk belastning för samhället. En viktig orsak till fallolyckor kan vara dålig balans. Kontrollen av upprätt stående och gångförmåga baseras på komplexa processer av neuromuskulär aktivitet. Denna neuromuskulära aktivitet bygger på sensorisk information från Control of the upright stance and locomotion is a complicated process of muscular activity. The muscular activity is dependant on afferent information from the different sensory organs and interpretation in the central nervous system. Age-related degenerative changes exist in all the domains concerned with control of posture. The aims of the studies were to investigate if suspected age-related de

In this work, we present an optical approach that allows quantification of compounds dissolved down to a sub 10 ppm (molar) level in supercritical carbon dioxide (scCO(2)) by in situ Raman spectroscopy. The quantification strategy is based on the consideration of Raman signal intensity ratios and of weak Raman signals of CO2. The first measure makes the quantification strategy independent of the r

The term ‘precarity’ has become increasingly popular as a way to capture the material and psychological vulnerability resulting from neoliberal economic reforms. This article demonstrates that such precarity is incompatible with democracy. More specifically, it makes two arguments. First, and inspired by Montesquieu’s analysis of ‘the principles’, or public commitments behind different forms of go

The argument has two related parts: firstly, we are witnessing an “epistemic” crisis in public spheres that threatens to undermine political agency. This crisis has to do with the massive amounts and speed of information, the processes by which we construct knowledge, as well as the new forms of knowledge deriving from digital technologies. Many developments in information technologies benefit dem

BackgroundLittle is known about health and wellbeing among patients with nephrotic syndrome (NS), despite it being a serious condition in patients with renal failure. In order to promote health, it is important that both healthcare professionals and patients are aware of the signs and symptoms of the disease.ObjectivesThe aim was to explore patients’ experience of suffering from nephrotic syndrome