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Register allocation by optimal graph coloring

We here present new insights of properties of real-life interference graphs emerging in register allocation. These new insights imply good hopes for a possibility of improving the coloring approach towards optimal solutions. The conclusions axe based on measurements of nearly 28,000 real instances of such interference graphs. All the instances explored are determined to possess the so-called 1-per

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

Recent studies have identified a number of transcriptional regulators, including E2A, early B-cell factor 1 (EBF1), FOXO1, and paired box gene 5 (PAX5), that promote early B-cell development. However, how this ensemble of regulators mechanistically promotes B-cell fate remains poorly understood. Here we demonstrate that B-cell development in FOXO1-deficient mice is arrested in the common lymphoid

Gamla kroppar och nya tekniker

Abstract in Finnish Inleding Dagen's biomedicinska utveckling bidrar till förbättrad livskvalitet för många människor. Det kan röra sig om nya läkemedel eller andra kliniska behandlingar med avgörande betydelse för en person's hälsotillstånd. Dessa medicinska möjligheter är emellertid inte helt oproblematiska. Ofta är stora ekonomiska kostnader förknippade, inte enbart med utvecklingsarbetet, men

Sociology and the New Institutionalism

In sociology, new institutionalists led the revival in interest in institutions in organizational theory and economic sociology by shifting the focus of causal reasoning from agent-centric studies of economic and organizational actors to the relationship connecting the firm with its institutional environment. We suggest a multilevel causal model incorporating the connection between the subinstitut

Improved microscopical diagnosis of pulmonary tuberculosis in developing countries

The diagnosis of pulmonary tuberculosis (TB) relies on the bacteriological examination of sputum. However, microscopy of smears made directly from sputum has a low sensitivity and there is an urgent need for improved methods. We have compared microscopy of smears made directly from sputum with microscopy after liquefaction of sputum with household bleach (NaOCl) and concentration of bacteria by ce

Fear of Moving Outdoors and Development of Outdoor Walking Difficulty in Older People

To study which individual characteristics and environmental factors correlate with fear of moving outdoors and whether fear of moving outdoors predicts development of mobility limitation. Observational prospective cohort study and cross-sectional analyses. Community and research center. Seven hundred twenty-seven community-living people aged 75 to 81 were interviewed at baseline, of whom 314 took

The patient with unilateral trans-tibial amputation for vascular disease : functional assessments, prognostic factors and cost of prostheses

Popular Abstract in Swedish Patienten med underbensamputation på grund av kärlsjukdom Långt före Kristi födelse var amputation av benet en känd operation. Anledningen till amputationen kunde vara kärlsjukdom, olycksfall, tumör eller medfödda missbildningar. I västvärlden idag utförs 90 % av amputationerna på grund av kärlsjukdom. Dessa patienter är äldre och sjukare än övriga benamputerade och meThe patient with unilateral trans-tribal amputation for vascular disease. Functional assessments, prognostic factors and cost of prostheses. The aims of the study were to focus on the functional ability of the dysvascular patient with unilateral trans-tibial amputation and the early rehabilitation period, defined here as the period between the amputation and the prosthetic fitting. Results revea

Tongue retraction is not so useful after all

This article reports model experiments where vocal tract profiles of high and mid unrounded front and high rounded back vowels were systematically modified to simulate small constriction shifts along the hard or soft palate, in order to test A. M. Bell's century-old proposal that small shifts of tongue arch fronting or retraction would yield audible shifts of vowel timbre. Such differences were cl

Shortened constraint-induced movement therapy in subacute stroke - No effect of using a restraint: A randomized controlled study with independent observers.

OBJECTIVE: To examine the effect of using a mitt during shortened constraint-induced movement therapy for patients in the subacute phase after stroke. SUBJECTS: Twenty-four patients with stroke (mean age 57.6 (standard deviation (SD) 8.5) years; average 7 weeks post-stroke) with mild to moderate impaired hand function. METHODS: The patients were randomized to mitt use or no mitt use on the less af

Evaluation of Wastewater Treatment Plant Operational Data by a Common Data Base System

The development of a common data base system for wastewater treatment operating data evaluation is discussed. Data records from wastewater treatment plants which have been converted into standard files in a common data base are used as a case study. Advanced programs for data analysis and simulation have been used to evaluate the data in the common data base. The paper discusses software standardi

The role of odor receptor protein Or22a in Drosophila melanogaster oviposition and the response spectra of chimeric receptor protein Or22a-b

Doftreceptor Or22a och dess betydelse för äggläggning hos bananflugor Vanliga bananflugor har länge använts som testorganismer inom biologisk forskning, så som neurobiologi. Anledningen till detta är att de har ett nervsystem som är lättillgängligt men enklare uppbyggt än däggdjurs (Stocker, 1994,). Luktsinnet hos bananflugor sitter i antennerna och i de maxillära papillerna, som sitter vid flugaThe fruit fly Drosophila melanogaster has a well-studied olfactory system. A crucial part of the olfactory system is the olfactory sensory neurons (OSNs). One type of these OSNs, Ab3a, expresses the Odor receptors (ORs) Or22a and Or22b. Or22a is known to play an important role for behaviors like oviposition, but no strong ligand has been found for Or22b. Recent studies have shown that D. melanogas