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Supporting Early Math : Rationales and Requirements for High Quality Software

There is substantial evidence that preschooler’s performance in early math is highly correlated to math performance throughout school as well as academic skills in general. One way to help children attain early math skills is by using targeted educational software and the paper discusses potential gains of using such software to support early math development. Furthermore it is argued that the con

A sequential method to identify underlying causes from industrial accidents reported to the MARS database

This paper presents a method designed to identify underlying causes leading to industrial accidents. The method developed intends to facilitate the learning process from accidents by identifying possible causes related to the accidents that were not directly stated in an accident report, but that can be deduced following the description of the event, in particular with regard to the quality of the

Underlying causes and level of learning from accidents reported to the MARS database

MARS is the system established and maintained by the European Commission in order to collect information related to major industrial accidents in EU Member States in the context of the Seveso II Directive. One of the main purposes of the MARS database is to provide information for learning from the accidents to avoid similar events. Probably, the most important issue for the learning is the determ

Austrian lichenologists exploring the Alps

Biographic sketches are provided for 19 of Austrian botanists who contributed in different ways to the knowledge on lichens of the European Alps: Othmar Breuss, Carl Wilhelm von Dalla Torre, Helmut Gams, Georg Gärtner, Martin Grube, Josef Hafellner, Karl von Keissler, Ernst Kernstock, Helmut Mayrhofer, Walter Obermayer, Josef Poelt, Karl Redinger, Julius Steiner, Elfriede Stocker-Wörgötter, Elisab

Biochemical and biomechanical modulation of the in vitro retina

The porcine retinal explant culture paradigm offers the possibility to study retinal health, disease and development independently from the surrounding tissues of the eye. Retina-intrinsic effects of molecular and mechanical cues on the isolated retinal sheet can thus be studied with great precision. For the purpose of creating a donor tissue optimized for transplantation, we used this system to e

Managing Hope and Spiritual Distress : The Centrality of the Doctor-Patient Relationship in Combatting Stem Cell Travel

Stem Cell travel refers to patients with a variety of diseases and debilitating disorders who travel abroad to receive unproven stem cell treatments. Current academic research investigating how to combat stem cell travel has yet to offer a complete understanding of the link between patient hope and autonomy, and building or losing trust in medical authorities. To combat stem cell travel, understan

Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity.

Optogenetic techniques provide powerful tools for bidirectional control of neuronal activity and investigating alterations occurring in excitability disorders, such as epilepsy. In particular, the possibility to specifically activate by light-determined interneuron populations expressing channelrhodopsin-2 provides an unprecedented opportunity of exploring their contribution to physiological and p

Yersinia pestis Ail recruitment of C4b-binding protein leads to factor I- mediated inactivation of covalently and noncovalently bound C4b

The outer membrane protein Ail of Yersinia pestis mediates several virulence functions, including serum resistance. Here, we demonstrate that Ail binds C4b-binding protein (C4BP), the primary fluid-phase regulator of the classical and lectin pathways. Non-covalent binding of C4 and C4b to Ail was also observed. C4BP bound to Ail can act as a cofactor to the serine protease factor I (fI) in the cle

MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+ Dendritic Cells Independently of TNF-α and the Gut Microbiota.

Intestinal homeostasis and induction of systemic tolerance to fed Ags (i.e., oral tolerance) rely on the steady-state migration of small intestinal lamina propria dendritic cells (DCs) into draining mesenteric lymph nodes (MLN). The majority of these migratory DCs express the α integrin chain CD103, and in this study we demonstrate that the steady-state mobilization of CD103(+) DCs into the MLN is

INITIAL INSIGHTS INTO THE STRUCTURE-ACTIVITY RELATIONSHIPS OF AVIAN DEFENSINS.

Numerous β-defensins have been identified in birds and the potential use of these peptides as alternatives to antibiotics has been proposed, in particular to fight antibiotic-resistant and zoonotic bacterial species. Little is known about the mechanism of antibacterial activity of avian β-defensins (AvBDs), and the present work was carried out to obtain initial insights into the involvement of str

On the Microlocal Properties of the Range of Systems of Principal Type

The purpose of this paper is to study microlocal conditions for inclusion relations between the ranges of square systems of pseudodifferential operators which fail to be locally solvable. The work is an extension of earlier results for the scalar case in this direction, where analogues of results by L. Hormander about inclusion relations between the ranges of first order differential operators wit

Pharmacological characterization and expression of VIP and PACAP receptors in isolated cranial arteries of the rat

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) are potent vasodilators in animals and humans. PACAP infusion but not VIP infusion precipitates migraine attacks in migraine patients. The vascular effects of VIP and the two varieties of PACAP (PACAP-27 and PACAP-38) were investigated versus selective antagonists in segments of rat middle cerebral arter

Exploring the balance between DNA pressure and capsid stability in Herpes and phage.

We have recently shown in both herpesviruses and phages that packaged viral DNA creates a pressure of tens of atmospheres pushing against the interior capsid wall. For the first time, using differential scanning microcalorimetry, we directly measure the energy powering the release of pressurized DNA from the capsid. Furthermore, using a new calorimetric assay to accurately determine the temperatur

Carelessness or Curatorial Chutzpah? Controversies Surrounding Street Art in the Museum

Taking the exhibition "Art in the Streets", which was shown at The Geffen Contemporary at the Museum of Contemporary Art, Los Angeles from 17 April to 8 August, 2011, as its main point of departure, the present article discusses street art's association with the institutions of the art world. "Art in the Streets" sparked a lot of debate before, while and after it took place. The article primarily

I’m a Believer – But I’ll Be Damned if I’m Religious : Belief and Religion in the Greater Copenhagen Area : A Focus Group Study

This book is a contribution to the discussion about religion in contemporary Western society, characterized by the privatization of religion. The concept religion is not easily operational and does not carry meaning or implications that remain valid or consistent over time. It must be re-substantiated in order to remain descriptive and operational. This book’s ambition is to explore a means of re-

An Approach to Analyze the Movements of the Arms while Walking using Wearable Wireless Devices

Abstract—Rhythmic movement of the arms while walking is an important feature of human gait. In this paper, we present an approach to analyze the movements of the arms while walking by using three wearable wireless devices placed around the torso. One of the devices is transmitter placed at the back and the other two are symmetrically placed receivers that record the power variation due to movement