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Moraxella catarrhalis is a major cause of exacerbations of chronic obstructive pulmonary disease (COPD) and emphysema. M. catarrhalis–specific UspA1 and the epithelial carcinoembryonic antigen-related cell adhesion molecule (CEACAM1) were required to induce apoptosis. M. catarrhalis–induced apoptosis was significantly enhanced in HeLa cells stably transfected with CEACAM1, compared with HeLa cells

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We explore whether off-the-shelf accounting solutions are used or not used in management control. This study explores the usage of accounting solutions such as ERP, “hybrid ERP”, and “best-ofbreed” (BoB). Previous research highlights the problem that ERP has a “moderate” impact on management control but no study addresses whether hybrid ERP and BoB adopters experience the same problem. The explora

BACKGROUND: HIV and other sexually transmitted infections are a growing problem in the military personnel of Africa, and information about this problem in Guinea-Bissau is lacking. The aims of this study were to determine the prevalence and trends of the HIV epidemics in the military forces of Guinea Bissau and to explore possible risk factors for HIV infection. METHODOLOGY: Repeated cross-sectio

Higher education has become a mega-topic in both political and scientific debate. Developments in systems of higher education and changes in the governance of such systems have been discussed in the literature. Such changes are brought about by collective actors within institutional settings. The present volume considers the policies of higher education supported by Social Democratic governments i

In preclinical research, allergic asthma is investigated in rats sensitised with the antigen ovalbumin (OVA), followed by a challenge with aerosolised OVA to induce an inflammatory reaction of the lower airways. This causes diffuse, nonfocal ventilation defects that lead to heterogeneously distributed signal intensities in hyperpolarised (HP) (3)He MR images, which are difficult to assess directly

Total gastrectomy or resection of the acid-producing part of the stomach (fundectomy) in the rat induced a marked and rapid reduction in bone wet weight, ash weight, and density (expressed as ash weight in mg/mm3 bone). Bone volumes were also affected but not as much. The radius, sternum, tibia, and femur were studied. Three weeks after gastrectomy the bone ash weight was reduced by almost 30% and

Plant size has been hypothesized to be a major driver of biotic interactions. However, it is little understood how plant size affects plant mutualists vs. antagonists and the plant's resulting reproductive success. We established a common garden experiment covering an interspecific plant size gradient (from 10 to 130 cm height) across 21 annual Brassicaceae species, thereby standardizing features

AbstractEndocarditis, or heart valve infection, can be caused by a number of pathogens, many of which are Gram-positive bacteria. The diagnosis is based on imaging techniques such as echocardiography and on blood culture. The implementation of fast and accurate species identification methods, such as the matrix-assisted laser desorption/ionisation-time of flight mass spectrometry (MALDI-TOF MS) in

Phagocytosis is measured as a functional outcome in many research fields, but accurate quantification can be challenging, with no robust method available for cross-laboratory reproducibility. In this study, we identified a simple, measurable parameter, persistent prey-phagocyte association, to use for normalization and dose-response analysis. We apply this in a straightforward analytical method, p

Background: Symptoms of depression and anxiety are common in children with obsessive-compulsive disorder (OCD) and associated with more severe OCD, greater impairment, and worse treatment outcome. Beyond twin studies showing that genetic factors contribute to the high co-occurrence, few studies have examined how OCD, depression, and anxiety are linked in youth, and current studies often fail to ac

Journal of Thrombosis and Haemostasis Supplement 1(3): abstract 1375. DOI: 10.1111/j.1538-7836.2005.03001.x

Although bone marrow (BM) represents the main site for postnatal NK cell development, recently a distinct thymic-dependent NK cell pathway was identified. These studies were designed to investigate the role of cytokines in regulation of thymic NK cells and to compare with established regulatory pathways of BM-dependent NK cell compartment. The common cytokine receptor gamma-chain (Il2rg) essential

Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies was generated against a major triple helical collagen type II (CII) epitope (position 359-369; ARGLTGRPGDA) with or without arginines modified by cit

Popular Abstract in Swedish Hoppet väcks för sömnsjuka Det sticker till i benet. Du viftar med handen, men alltför långsamt. Du ser en glimt av den ljusbruna flugan, stor som ett bi, och hör hur den surrar vidare genom den varma afrikanska eftermiddagen mot sitt nästa blodmål. Tsetseflugans bett kliar. Inom ett par dagar har det förvandlats till en arg röd svullnad. Därinne förökar sig parasiternIn the last decade, powerful communication and information technology in the form of the mobile phone has been put into the hands of more than 50% of the global population. In stark contrast, a lack of access to medical diagnostic technology with which to diagnose both communicable and non-communicable diseases will mean that many of these people will die of easily treatable conditions. Small, por