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Comprehensive Mass Spectrometric Survey of Streptococcus pyogenes Subcellular Proteomes

Streptococcus pyogenes is a major global health burden causing a wide variety of diseases. Because a vaccine against this bacterium is still lacking, vaccine candidates or antimicrobial therapies are urgently needed. Here we use an invasive and clinically relevant streptococcal M1 serotype to characterize the bacterial proteome in-depth. An elaborate fractionation technique is employed to separate

Underwater terrain navigation during realistic scenarios

Many ships today rely on Global Navigation Satellite Systems (GNSS), for their navigation, where GPS (Global Positioning System) is the most well-known. Unfortunately, the GNSS systems make the ships dependent on external systems, which can be malfunctioning, be jammed or be spoofed. There is today some proposed techniques where, e.g., bottom depth measurements are compared with known maps using B

Learning through collaboration in the Swedish public transport sector? Co-production through guidelines and living labs

The purpose of the paper is to analyse informal collaboration in the public transport sector. Two Swedish case studies, Living lab Uddevalla and Guidelines for Regional BRT are analysed and compared concerning what kind of learning occurred and what lessons regarding informal collaboration to draw from the two cases. For both cases the analysis indicates that individual, single loop learning is th

A strategic and comprehensive vision for future R&D in construction ICT

The tremendous development in the past ten last years of the Internet and ICT at large (whether it be in general technologies like semantic modeling, knowledge mining, RFID or mobile technologies, or domain-oriented ones like e-commerce, collaborative spaces, digital mock-ups, etc.) has opened a large spectrum of potential applica-tions of ICT in the Construction sector. The real adaptation and de

ICTV virus taxonomy profile : Papillomaviridae

The Papillomaviridae is a family of small, non-enveloped viruses with double-stranded DNA genomes of 5 748 to 8 607 bp. Their classification is based on pairwise nucleotide sequence identity across the L1 open reading frame. Members of the Papillomaviridae primarily infect mucosal and keratinised epithelia, and have been isolated from fish, reptiles, birds and mammals. Despite a long co-evolutiona

European Society for Immunodeficiencies (ESID) and European Reference Network on Rare Primary Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN RITA) Complement Guideline : Deficiencies, Diagnosis, and Management

This guideline aims to describe the complement system and the functions of the constituent pathways, with particular focus on primary immunodeficiencies (PIDs) and their diagnosis and management. The complement system is a crucial part of the innate immune system, with multiple membrane-bound and soluble components. There are three distinct enzymatic cascade pathways within the complement system,

Imagination

Imagination is a human capacity that reproduces and transforms experiences and thoughts. The capacity is manifested in children’s pretend play and is an important part of adults’ ability to process the past, and to plan the future. A first step in the development of imagination is the ability to represent objects and events and to change these representations into alternatives to reality. For adap

Paralympic athletes’ perceptions of their experiences of sports-related injuries, risk factors and preventive possibilities

Our knowledge of sports-related injuries in para-sport is limited and there are no data on how Paralympic athletes themselves perceive an injury. The aim of this qualitative study was to explore Paralympic athletes’ perceptions of their experiences of sports-related injuries, risk factors and preventive possibilities. Eighteen Swedish Paralympic athletes with vision impairment, intellectual impair

Multilingual Supervision of Semantic Annotation

In this paper, we investigate the annotation projection of semantic units in a practical setting. Previous approaches have focused on using parallel corpora for semantic transfer. We evaluate an alternative approach using loosely parallel corpora that does not require the corpora to be exact translations of each other. We developed a method that transfers semantic annotations from one language to

On strategies of plant behaviour : Evolutionary games of habitat selection, defence, and foraging

Background: Strategies of habitat selection, defence, and foraging depend critically on population density and the frequency of alternative strategies: they are evolutionary games. Although commonly modelled in studies of animal behaviour, they are less frequently used to provide insights into the behaviour of plants. A 'review' and analysis of how these universal strategies apply to plants should

Living with persistent rheumatoid arthritis : A BARFOT study

Aim and objective: To describe and understand the meaning of living with persistent rheumatoid arthritis. Background: A considerable number of patients with rheumatoid arthritis live with an ongoing active and symptomatic illness despite access to potent antirheumatic treatment. There is, however, a lack of knowledge about the meaning of living with this severe long-term illness, defined as persis

Stochastic model for the investigation of the influence of turbulent mixing on engine knock

A stochastic model based on a probability density function (PDF) was developed for the investigation of different conditions that determine knock in spark ignition (SI) engine, with focus on the turbulent mixing. The model used is based on a two-zone approach, where the burned and unburned gases are described as stochastic reactors. By using a stochastic ensemble to represent the PDF of the scalar

Konstruktion av genus i rätten och samhället : en tvärvetenskaplig studie av svenska kvinnors rätt till jämställdhet i ett formellt jämlikt rättssystem

Popular Abstract in Swedish I avhandlingen belyses den inneboende konflikt som finns mellan de två snarlika begreppen jämställdhet och jämlikhet. Detta görs genom att fokusera på svenska kvinnors rätt till jämställdhet i ett formellt jämlikt rättssystem ur ett tvärvetenskapligt feministiskt perspektiv. Det betyder att även om jag har tagit min utgångspunkt i den svenska jämställdhetslagen har jag On the first of January 1992 the present Equal Opportunity Act came into force. A central aim of this law is to improve the conditions of women's working life. One aspect of the law is the possibility to serve as a mean of shifting the balance of power between the sexes. This is meant to be achieved through the inclusion of requirements for active measures to promote equality. As a part of their s

Friction and Damage Accumulation, Formation, Morphology and Transport of Dust from Fibre Handling

The mechanical stress build up in fibre handling, the dynamical frictional phenomena between fibres and curves surfaces and formation of dust have been studied. Typical are stick slip behaviour and threshold stress levels for formation of dust. The emissions of dust can be limited by electrostatic charging. The measured coefficients of friction of the fibres depend on the mechanical properties, mi

An Opportunistic Backoff Scheme for Dense IEEE 802.11 WLANs

In dense deployments, the performance of IEEE 802.11 Wireless Local Area Networks (WLANs) depends on the development of efficient contention resolution mechanisms since the collision probability can be high even with low number of users with the current 802.11 MAC mechanism. Also, the current 802.11 MAC is not opportunistic in the sense that it does not consider channel quality and traffic load of

Comparing East Asian and Scandinavian Redistribution Models in a Global Context

In this paper we discuss social policy in relation to different development contexts, where characteristics and outcomes of social policies in different sectors ( e.g.,housing, care, education, social security) are compared. The paper relates to the discussion on the causes and outcomes of welfare state management in different contexts. However, existing analytical models do not fit the mixtures o