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BACKGROUND: Although intensive blood pressure (BP) control has not been shown to slow the progression of chronic kidney disease (CKD), intensive BP control has been shown to reduce the risk for adverse cardiovascular outcomes in the CKD population. The aim of this post-hoc study was to study the interplay between a self-monitoring BP system and glomerular function.METHODS: In all, 949 participants
The Colombian peace agreement, which has brought an end to a prolonged internal armed conflict has led to significant land use changes that underscore existing inequalities and struggles over natural resources. The expansion of industries such as cattle ranching, agriculture, and extraction is encroaching on indigenous territories and protected areas, resulting in negative consequences for communi
Recension av Nduduzo Makhathini, 2023. Breaking into sound: dis/locating ntu cosmology and improvisation in South African jazz. Diss. Stellenbosch: Faculty of Arts and Social Sciences, Stellenbosch University. 239 pp. + audio/video links.
In the context of global warming, escalating water cycles have led to a surge in drought frequency and severity. Yet, multidecadal fluctuations in drought and their multifaceted influencing factors remain inadequately understood. This study examined the multide-cadal changes in drought characteristics (frequency, duration, and severity) and their geographical focal points within China’s north-sout
Allegiance is a legal concept that seeks to regulate the duty of fidelity of individuals towards states. A particularity of allegiance is the fact that it has been repeatedly used in treaty provisions, as well as interpretation of rules, in the field of International Humanitarian Law. The fields in which it has been introduced are quite broad, from rules relating to Prisoner of War status, to defi
Dining plays a pivotal role in the travel experience, with numerous studies identifying the significant impacts of restaurant attributes on tourists’ destination experiences and their sense of place. The identified attributes include the origin of food produce, menu design, the physical and social servicescape, and restaurant reputation, all of which have the potential to enhance customers’ sense
Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR
This study focuses on the contexts of language experience in relation to language dominance in eighty-seven Italian–German primary school children in Germany using the MAIN narrative task. We compare current language experience in the heritage language (Italian) and the majority language (German) in both formal and informal settings, and we examine the respective impact on micro- and macrostructur
Background: Food biodiversity in human diets has potential co-benefits for both public health and sustainable food systems. However, current evidence on the potential relationship between food biodiversity and cancer risk, and particularly gastrointestinal cancers typically related to diet, remains limited. This study evaluated how dietary species richness (DSR) was associated with gastrointestina
Study region: Rönne River, Säve River, and Höje River, Sweden. Study focus: River-induced flooding in coastal areas results from a multitude of drivers interacting in complex ways. The primary drivers are sea level (SL) and river flow (Q) that often exhibit coherent behavior to be considered in flood risk management. To describe and quantify the compound effects of SL and Q on flooding, a methodol
Background: The ankle–brachial index (ABI) is the ratio of the ankle and brachial systolic blood pressures. In the clinical setting, low ABI (< 0.9) is an indicator of peripheral atherosclerosis, while high ABI (> 1.4) is a sign of arterial stiffness and calcification. The purpose of the current study was to investigate the association between ABI and physical activity levels, measured by accelero
Context: Medications may become inappropriate for patients in the last phase of life and may even compromise their quality of life. Objective: To find consensus on recommendations regarding deprescribing of medications for adult patients with a life expectancy of six months or less. Methods: Experts working in palliative care or other relevant disciplines were asked to participate in this internat
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain insulin resistance remain unexplored. Abnormal biliverdin reductase-A (BVR-A) levels were observed in both T2D and AD and were associated with insulin resistance. Here, we demonstrate that re
BACKGROUND:Postural orthostatic tachycardia syndrome (POTS) is a frequently diagnosed cardiovascular disorder after COVID-19 infection. POTS is characterized by the presence of excessive sinus tachycardia on standing without a fall in blood pressure (BP). We investigated the BP profile using 24-hour ambulatory BP monitoring in patients with new-onset POTS after COVID-19 compared with prepandemic p
Schisandrin B (Sch B) is a predominant bioactive lignan from the fruit of a Chinese medicine food homology plant, Schisandra chinensis. Previously, we observed potent anti-tumor effect of Sch-B in colorectal cancer (CRC) and enhanced chemotherapy efficacy with fluorouracil (5-FU). However, their bioavailability and reciprocal interactions under CRC conditions are unclear. In this study, we first c
Vaccine hesitancy (VH) is an issue for healthcare students, influenced by safety concerns and misinformation. The need for better communication training and understanding sociocultural factors in VH was highlighted in a European University Alliance seminar. Practical exercises like simulation role-playing, interprofessional collaboration, and digital literacy may improve vaccine education.
This study uses an experimental scale-up model together with a high-speed camera setup to quantitatively study the effect of Weber number on the breakup probability, deformation time, breakup time, breakup position, and breakup rate in this geometry in a turbulent jet. Results show an increase in breakup probability and a decrease in deformation and breakup times with increasing Weber number. Brea
This article traces publishing patterns in the Swedish humanities between 1840 and 1880; a period characterized by a new publishing regime yet bridging two dominant publication forms, the dissertation, and the disciplinary journal. Using the prominent historian Wilhelm Erik Svedelius as an entry point, the article charts how scholars in the humanities navigated the publishing landscape in a more d
Background: Patients in palliative care are often treated with antithrombotics, even in the late stages of disease. Clear guidelines regarding deprescribing are lacking. Objective: The aims of this study were to investigate bleeding as a side effect of antithrombotic treatments the last year in life and map the timing of deprescribing. Methods: A retrospective cohort study was performed. All medic
