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Background: Renalase (gene name RNLS), a recently discovered enzyme with monoamine oxidase activity, is implicated in the degradation of catecholamines. Recent studies delineate a possible role of this enzyme in blood pressure (BP) maintenance and cardiac protection and two single nucleotide polymorphisms, RNLS rs2576178 A > G and rs2296545 C > G have been associated with hypertension. The latter
Basal ecosystem respiration rate (BR), the ecosystem respiration rate at a given temperature, is a common and important parameter in empirical models for quantifying ecosystem respiration (ER) globally. Numerous studies have indicated that BR varies in space. However, many empirical ER models still use a global constant BR largely due to the lack of a functional description for BR. In this study,
Objective: To investigate (i) the performance and agreement between various activity indices and response criteria in TNF-blockade of RA; (ii) the predictive ability of different response criteria and disease activity states regarding continuation of anti-TNF treatment of RA; (iii) Euro-QoL-5-dimensions utility development during TNF blockade of RA, PsA and SpA. Also, (iv) to develop a simple, uti
Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and similar to 2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci
Waste is an issue in the food industry which impacts both the economy and the environment negatively. Atria is a food company aiming to reduce the waste. This report investigates the waste, its origin, and causes in the ham production process. The aim of this report is to identify waste and possible solutions. In this report both qualitative data and quantitative data were collected and analysed.
For an autonomous system of linear differential equations we are able to determine stability and instability with classical criteria, by looking at the eigenvalues. If the system is stable, all the eigenvalues have negative real part and if the system is unstable, there exist at least one eigenvalue with positive real part. However, if it were to be nonautonomous, the criterion fails. There exis
Agreements with SKR (Swedish Association of Local Authorities and Regions) have emerged as a significant steering instrument for the Ministry of Health and Social Affairs (MHSA). The agreements define activities for the Local Authorities to carry out and nearly always include earmarked grants. No study has yet explained why agreements are utilized as a steering instrument. Therefore, this study se
This thesis investigates the application of spline regression models to predict the Probability of Default (PD) under varying macroeconomic conditions, exploring whether these models can enhance predictive accuracy over traditional linear models and compare favorably to XGBoost. The study analyses the non-linear dynamics between PD and key macroeconomic indicators within a Swedish small-sized corp
This master thesis explores the Corporate Sustainability Due Diligence Directive (CSDDD) within the European Union, focusing on how it integrates the concept of double materiality into corporate governance. The directive mandates that companies not only account for the financial impact of sustainability on their operations but also consider their broader environmental and societal effect. This stu
It has been proposed that vascular progenitor cells play an important role in vascular repair, but their possible clinical importance in cardiovascular disease has not been fully characterized. Vascular endothelial growth factor A, placental growth factor and stem cell factor (SCF) are three growth factors that are important in recruiting vascular progenitor cells. In this study, we investigated t
The payment method is under transition making the world step into a digital and mobile oriented chapter. With the development of integration between internet technology and financial functions, China expects to have a large number of mobile payments from its citizens as a result of the population size. The growth and development of e-commerce and the rise of online shopping have contributed much t
Copolymers of 1,5-dioxepan-2-one (DXO) and L- or D,L-dilactide have been synthesized and characterized. The molar ratio of the two monomers was around 20/80 of DXO and L- or D,L-lactide respectively. In vivo studies on rats revealed significant differences in tissue response between the semicrystalline DXO/L-LA copolymer and the amorphous DXO/D,L-LA copolymer. The materials were characterized pre-
In this study, we investigate how prosodic cues are used when an overt pronoun is associated with either a subject or an object antecedent in Italian and in Swedish. To address this question, 28 Italian speakers and 28 Swedish speakers completed a production task, by reading out loud globally-ambiguous sentences containing overt pronouns and a control interpretation task, where they selected eithe
Atrial natriuretic peptide (ANP) represents an attractive therapeutic target in hypertension and heart failure. The biologically active form of ANP is produced by the cardiac serine protease corin, and modulation of its activity might therefore represent a novel approach for ANP augmentation. MicroRNAs (miRNAs) are pervasive regulators of gene expression, but their potential role in regulating cor
Purpose – As climate change shocks and stresses increasingly affect urban areas in developingcountries, resilience is imperative for the purposes of preparation, recovery and adaptation. This study aims to investigate demographic characteristics and social networks that influence the household capacity to prepare, recover and adapt when faced with prolonged droughts or erratic rainfall events in M
Background: It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF. Methods and Results: In this nationwide study of the Swedish population, patients with AF and t
Cardiovascular disease (CVD) is the most common cause of death in industrialized countries. One underlying cause is atherosclerosis, which is a systemic disease characterized by plaques of retained lipids, inflammatory cells, apoptotic cells, calcium and extracellular matrix (ECM) proteins in the arterial wall. The biologic composition of an atherosclerotic plaque determines whether the plaque is
Egypt’s area is approximately 1.002 million km². However, the population and economic activity are concentrated along the banks of the Nile, where the urbanization rate is approximately 7.8%, while the rest of the land is considered desert. This population and spatial density has prompted both the public and private sectors to consider and seek solutions represented by building new urban communiti
This thesis examines state and nationalist narratives regarding four Russian national holidays: Defender of the Fatherland Day, Victory Day, Russia Day, and National Unity Day. The study was motivated by the observation that existing scholarship on Russian commemorative politics focuses almost exclusively on Victory Day, practically ignoring other national holidays, the examination of which reveal
