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This study evaluates how well five Regional Climate Model (RCM) projections at resolutions from 44 km to 3 km reproduce wet and dry spells compared with observations at six locations in Scania, southern Sweden. Future changes in general and extreme wet and dry signals were also analyzed under RCP8.5 to the end of the 21st century. Convection-permitting climate models (CPMs), operating at resolutio
whiE is a complex locus that specifies the polyketide spore pigment in Streptomyces coelicolor A3(2). Two divergently oriented promoters, whiEP1 and whiEP2, were identified in the whiE gene cluster, and their activities were analyzed during colony development in wild-type and sporulation-deficient strains. Both promoters were developmentally regulated; whiEP1 and whiEP2 transcripts were detected t
In this work, we have studied how the choice of the continuous phase oils affects droplet-internal acoustic manipulation and mapped the acoustic properties of the selected oils to evaluate their compatibility with droplet acoustofluidic methods. The selection of continuous phase included hydrocarbon, fluorinated, and silicone oils. To map the acoustic properties of the oils, we measured their spee
Thirteenth-century interpreters of Aristotle’s Topics put forward metaphysical accounts aiming to underpin Aristotle’s account of dialectical argumentation. The reason for this, I surmise, is that they took Aristotelian logic to be a scientific method, a crucial part of which is the dialectical method provided in the Topics. Dialectical arguments proceed distinctively from acceptable premises whic
BACKGROUND: The discrepancy between experimental research and clinical trial outcomes is a persistent challenge in preclinical studies, particularly in stroke research. A possible factor contributing to this issue is the lack of standardization across experimental stroke models, leading to poor reproducibility in multicenter studies. This study addresses this gap by aiming to enhance reproducibili
Wind energy is an increasingly viable solution for sustainable power generation, particularly in developing regions with high wind potential. This paper presents a comprehensive analysis of the wind power and energy output estimation for the Sela Dingay wind farm, a candidate site in Ethiopia. The study utilizes measured wind speed data at 50 meters and interpolates it to different hub heights (91
BACKGROUND AND OBJECTIVE: A post hoc analysis of TITAN evaluated the clinical benefit of apalutamide plus androgen-deprivation therapy (ADT) versus ADT alone in metastatic hormone-sensitive prostate cancer (mHSPC) with high disease burden. METHODS: Patients were assessed in subgroups of those with four to fewer than ten, ten to <20, or ≥20 bone metastases; with lung but not liver metastases; and w
Intro: Population-based studies predominantly focused on carcinoma of the parotid gland (CPG) are rare. The study aims were to analyze the incidence of CPG and to assess treatment outcomes in relation to histopathology, preoperative diagnosis and adjuvant radiotherapy. Methods: A retrospective analysis was conducted on data from the Swedish Head and Neck Cancer Register (SweHNCR), including 1,018
BACKGROUND AND AIMS: Atherosclerotic plaques are the leading cause of cardiovascular events. Single-cell approaches have identified diverse human plaque cell phenotypes but their spatial distribution and interactions remain unclear. Here, intercellular communication patterns in human plaque microenvironments were mapped to reveal novel targets to prevent atherosclerotic events.METHODS: Spatial tra
Hypothalamic inflammation underlies diet-induced obesity and diabetes in rodent models. While diet normalization largely allows for recovery from metabolic impairment, it remains unknown whether long-term hypothalamic inflammation induced by obesogenic diets is a reversible process. In this study, we aimed at determining sex specificity of hypothalamic neuroinflammation and gliosis in mice fed a f
Background: Globally, undernutrition is responsible for over 3.5 million deaths among children under the age of 5. In Mozambique, it remains a major contributing factor to the high rates of child mortality and illness. Essential micronutrients like zinc, iron, and calcium play a vital role in healthy growth and development. However, their absorption is hindered by anti-nutrients such as phytates,
The pathophysiology underlying various manifestations of cerebral small-vessel disease (cSVD) remains poorly understood. Using high-throughput proteomics, we identified common and distinct proteomic signatures of white matter lesions (WMLs), microbleeds, infarcts and their subtypes, measured in 1,670 living patients. Across all cSVD manifestations, markers of extracellular matrix dysregulation and
One of the major subfields of chemical ecology is the study of toxins and how they mediate interactions between organisms. Toxins produced by harmful algae (phycotoxins) impact a wide variety of organisms connected to the marine food web. Significant research efforts have thus aimed to identify the ecological and evolutionary drivers behind harmful algal blooms (HABs) to facilitate their forecasti
This review synthesises current evidence on the clinical utility of foam-based posturography in the assessment of vestibular pathologies. It critically evaluates: (1) the physiological mechanisms underlying foam posturography and its capacity to determine vestibular contributions; (2) methodological variability across testing protocols, including differences in foam properties, stance conditions a
In 2024, the European Academy of Paediatrics (EAP) published a list of 10 low-value practices in paediatric care. Embedded in the Choosing Wisely framework, this list is a step towards promoting targeted and evidence-based care. However, no single recommendation can change prescription habits and we need to acknowledge that overuse of the available resources has multiple causes. Among them, the ph
An attempt was made to create a museum that focuses on the issues of democracy, migration and human rights by the Swedish authorities in 2015. As a result of the feasibility study of such an institution, the Museum of Movements (MoM) began to operate in its temporary location in Malmö. In September 2020, it was decided that the museum would no longer be financed by the Swedish government and the d
The aim of the thesis is to analyse the current role of management accountants, how it is affected by contextual factors, and how it has changed over time. A quantitative content analysis of job advertisements is conducted. The factors of analysis are identified based on a combination of deductive and inductive approach. First, reporting, planning, budgeting, forecasting, cost accounting, MS Offi
Purpose: The primary aim of this study is to assess current environmental reporting undertaken by oil and gas companies in Europe with respect to COP 21. Methodology: This study is exploratory in nature. By developing an environmental performance assessment framework incorporating COP 21 requirements and oil and gas industry specific voluntary disclosure guidelines, a qualitative content analysis
