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Four randomized studies show that adjuvant radiotherapy (RT) lowers the risk of subsequent ipsilateral breast events (IBEs) after breast-conserving surgery (BCS) for ductal carcinoma in situ (DCIS) by approximately 50% after 10 to 15 years. We present 20 years of follow-up data for the SweDCIS trial.
This paper presents an analysis of a regional transport infrastructure plan in Sweden. A comparison is made of two concepts central to transport infrastructure planning in Sweden; Regional expansion and Environmentally sound transport. These concepts signify different perspectives on the benefits and problems with transport. The analysis explains how these clashing perspectives are resolved in the
Abstract in UndeterminedBACKGROUND: . This study examines inequalities in health in Laos. Because perception of health might affect ratings, we used both a global and a relative self-rated health (SRH) question. METHODS: . The study was based on the fourth Lao Expenditure and Consumption Survey, 2007-2008. The study population consisted of 24 162 individuals 20 years or older. Two single-question
Quantitative information about outdoor thermal comfort, on various temporal and spatial scales, is required to design better cities and mitigate heat problems not only in warm but also in temperate climates. The overall objective of this study is to explore the augmentation of global/regional climate changes by urban features such as geometry in a compact mid-rise high-latitude city (Gothenburg).
Dietary fats could affect glucose metabolism and obesity development and, thereby, may have a crucial role in the cause of type 2 diabetes (T2D). Studies indicated that replacing saturated with unsaturated fats might be favorable, and plant foods might be a better choice than animal foods. Nevertheless, epidemiologic studies suggested that dairy foods are protective.
Objective-To study how Niemann-Pick disease type C1 (NPC1) influences hepatic triacylglycerol (TG) metabolism and to determine whether this is reflected in circulating lipid levels. Methods and Results-In Npc1(-/-) mice, the hepatic cholesterol content is increased but the TG content is decreased. We investigated lipid metabolism in Npc1(-/-) mouse hepatocytes and the association of NPC1 single-nu
BACKGROUND The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of
We prospectively evaluated fat intake as predictor of developing breast cancer (BC) subtypes defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 receptor (HER2), in a large (n = 337327) heterogeneous cohort of women, with 10062 BC case patients after 11.5 years, estimating BC hazard ratios (HRs) by Cox proportional hazard modeling. High total and satu
Although infectious diseases kill around 17 million people a year, some states spend less then one percent of their budget on health. The promotion and protection of health is a fundamental condition for well being and the possibility to leave a life in dignity. The world has now for 20 years been facing an extremely dangerous epidemic. In Vietnam the first HIV infection was reported in 1990 and t
Through a deductive content analysis, this paper aimed to elucidate a place for critical literacy as an educational approach based on research by Lewison, Flint and Van Sluys in the Swedish curricula for upper secondary school, GY2000 and Lgy11, respectively. After reading research by Cabau and Hult, showing how the curricula propagates the position of English in the curriculum, and the Swedish so
Syftet med studien är att undersöka om investeringsstrategin ”Dogs of the Dow” har genererat överavkastning på Stockholmsbörsen under perioden 1988-2015, jämfört med relevant index. Avkastningen jämförs med hänsyn till transaktionskostnader, skatter och risk. Författarna undersöker om det finns en statistiskt signifikant skillnad i avkastningen och risken mellan investeringsstrategin och jämförels
År 1997 byggdes en havsvall i Isahaya bukten i Ariake havet, Japan, för att återta land för lantbruk och översvämningskontroll. Den här studien undersöker hur havsvallen har påverkat den barokliniska strukturen i Ariake havet och bildandet av hypoxiskt vatten i Ariake havet genom att fokusera på påverkan från förflyttningen av utflödet av färskvatten, den tidsmässiga förändringen för utflödet av fIn 1997 the Isahaya Sea Dike was built in the head of Isahaya Bay which is a branch of the Ariake Sea, Japan, with the aim of reclaiming land for agriculture and flood control. This study examines how the Isahaya Sea Dike has affected the baroclinic structure and development of hypoxic waters in the Ariake Sea by focusing on the spatial change of freshwater discharge, the temporal change of freshw
The following thesis investigates political culture in Russia, focusing on the attendants in the protests for fair elections between 2011-2013. The study grounds in the ambivalent Russian youth that on the one hand are described as Putin’s ‘puppets’, and on the other hand are the main actors in protests against electoral fraud and corruption. The thesis focuses further in identifying support for p
Cross-presentation is an essential mechanism of the immune system when it comes to fighting viruses and tumors. Oropharyngeal cancer (OPC), which can affect tonsillar tissue, is highly associated with high-risk human papillomavirus (HPV) infections and CD8+ T-cells directed towards killing HPV-infected cells could prove to be a promising treatment of HPV-induced OPCs. In this study, the expression
As a result of 20th-century car-centric planning, many urban districts had emerged designed to serve only one function. Different residential suburbs and trade areas were dispersed scattered within and outside the cities. This has led to more dependence on private cars to meet people’s daily needs. Urban Ergonomics will discuss one type of these areas, the external shopping centers, or the big-bo
Energy transition is crucial to mitigate the impacts of climate change globally. Solar energy, particularly through photovoltaic (PV) technology, plays a critical role in this transition. Innovation within the solar PV industry is essential, and policy support, especially government subsidies, is crucial for its technological advancement. This study focuses on China’s solar PV industry given its l
Som en del i klimatomställningen av svåråtkomliga sektorer som sjöfart, flyg, och kemiindustri kan elektrobränslen komma att spela en viktig roll. I Sverige har e-metanol väckt intresse, och flera produktionsanläggninar är planerade eller under byggnation. Dessa kommer att vara stora elkonsumenter, men på grund av den traditionellt icke-flexibla metanolsyntesprocessen finns det frågetecken kring hAs a part of the climate transition of hard-to-abate sectors such as shipping, aviation, and chemical industry, electrofuels may play a key part. In Sweden, e-methanol has gained interest, and several production facilities are currently planned or under construction. These will be very large electricity consumers, but because of the traditionally inflexible methanol synthesis they may not be able
