Filetype
Twitter's open network structure enables us to quickly and easily share our political thoughts and views. But how well does social media provide an arena for a rich political conversation? The aim of this thesis is to provide knowledge about the digitized political dialogue, citizens' abilities to influence through public discussion and the conditions Twitter as a platform provides for an
Melanin is a group of pigments present in almost all kingdoms of life. It has many interesting properties such as high fossilizing potential and the ability to chelate metals. The binding of metal ions is believed to have two major functions within biological systems: metal reservoir and metal scavenger. However, eumelanin’s chemical structure is still unknown and there is a knowledge gap regardin
Context: CCAAT/enhancer binding protein alpha (C/EBPalpha) is a transcription factor involved in adipogenesis and hepatic glucose and lipid metabolism. Objective: To test the hypothesis that adipose tissue C/EBPalpha regulates genes in lipid and glucose metabolism and to test for association between a polymorphism in C/EBPalpha and metabolic parameters. Design and Methods: Adipose tissue C/EBPalph
BACKGROUND: The aim of the study was to examine associations between intake of macronutrients and dietary fiber and incident ischemic cardiovascular disease (iCVD) in men and women. METHODS: We used data from 8,139 male and 12,535 female participants (aged 44-73 y) of the Swedish population-based Malmö Diet and Cancer cohort. The participants were without history of CVD and diabetes mellitus, and
We have examined a family with a germline BRCA2 mutation in three cases of invasive breast cancer and one case of ductal carcinoma in situ ( DCIS). Loss of heterozygosity (LOH) has been demonstrated at the BRCA2 locus in all cases. This result may suggest that the germline mutation in BRCA2 is the initiating step of DCIS and support the theory that DCIS is a precursor of invasive breast carcinoma
Bakgrund Löpning som aktivitet är ett tillgängligt sätt att nå upp i de rekommendationer om fysisk aktivitet som ges av FYSS (fysisk aktivitet i sjukdomsprevention och sjukdomsbehandling). Löpning för med sig ett flertal hälsofördelar, bland annat förbättrad mental och kardiovaskulär hälsa. Trots dessa fördelar är det vanligt att löpare drabbas av skador på det muskuloskeletala systemet. Dessa ska
Historiska institutionen Lunds universitet HISA02, vt 2017 Lärare: Klas-Göran Karlsson (KGK) klas-goran.karlsson@hist.lu.se & Ulf Zander (UZ), ulf.zander@hist.lu.se . Övrig lärare: Anna Wallette (AW) anna.wallette@hist.lu.se HISA02: Katastrofernas århundrade Denna kursplanering ger en grov översikt över vad som tas upp vid de olika undervisningstillfällena. Förbered dig genom att före lektionstill
https://www.historiska.lu.se/media/utbildning/dokument/kurser/HISA02/20171/Krschema_HISA02_vt_17.docx - 2026-07-17
Obesity’s metabolic heterogeneity is not fully captured by body mass index (BMI). Here we show that deep multi-omics phenotyping of 1,408 individuals defines a metabolome-informed obesity metric (metBMI) that captures adipose tissue-related dysfunction across organ systems. In an external cohort (n = 466), metBMI explained 52% of BMI variance and more accurately reflected adiposity than other omic
Forests are integral to the global carbon cycle, acting as major carbon sinks, though their capacity can be altered by climate and land use changes. India has a diverse forest ecosystem, but the dynamics and changes in its carbon stocks under a changing climate are not well understood. This study investigates the regional and temporal changes in vegetation carbon biomass (VCB) within Indian forest
Monitoring atmospheric CO2 concentration changes across China is crucial for reducing carbon emissions and tackling global warming. Due to monitoring gap in satellite observations, this paper uses the Extremely Randomized Trees (ERT) model alongside OCO-2 satellite data and predictor variables to develop a 0.1° high-resolution monthly dataset of column-averaged dry air CO2 mole fraction (XCO2) in
Monitoring ecosystems at regional or continental scales is paramount for biodiversity conservation, climate change mitigation, and sustainable land management. Effective monitoring requires satellite imagery with both high spatial resolution and high temporal resolution. However, there is currently no single, freely available data source that fulfills these needs. A seamless fusion of data from th
Impacts of elevated tropospheric ozone on mountain birch leaves reveals higher vulnerability in young leaves compared to old. The leaf recovery after high concentration exposure is affected with lower photosynthetic rate and increased stress-related sesquiterpene emissions.
Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SRμCT) has become a tool for extending the imaging of two-dimensional thin sections into three-dimensional imaging of tissue blocks, enabling so-called virtual histology with arbitrary clipping planes, volumetric renderi
Novel methods to characterize the plasma proteome has made it possible to examine a wide range of proteins in large longitudinal cohort studies, but the complexity of the human proteome makes it difficult to identify robust protein-disease associations. Nevertheless, identification of individuals at high risk of early mortality is a central issue in clinical decision making and novel biomarkers ma
Background and aims: Genetic loci associated with CHD show different relationships with intima-media thickness in the common carotid artery (IMT-CCA) and in the bulb (IMT-bulb). We evaluated if IMT-CCA and IMT-bulb differ also with respect to circulating protein profiles and risk of incident atherosclerotic disease. Methods: In three Swedish cohorts (MDC, IMPROVE, PIVUS, total n > 7000), IMT-CCA a
BACKGROUND: Cerebral endothelial dysfunction occurs in a spectrum of neurodegenerative diseases. Whether biomarkers of microvascular endothelial dysfunction can predict dementia is largely unknown. We explored the longitudinal association of midregional pro-atrial natriuretic peptide (MR-proANP), C-terminal endothelin-1 (CT-proET-1) and midregional proadrenomedullin (MR-proADM) with dementia and s
Background: Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood cancers. Therefore, we aimed to provide the most detailed overview of the long-term risk of hospitalisation in survivors of childhood cancer. Metho
BACKGROUND: Increased somatostatin plasma concentration has been found in patients with vascular dementia. However, it is unknown whether or not somatostatin levels may predict dementia development in the general population. To this end, we sought to assess the association of circulating N-terminal prosomatostatin (NT-proSST) with incident dementia among community-dwelling older adults.METHODS: In
