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The charge and proton dynamics in hydrogen-bonded networks are investigated using ammonia as a model system. The fragmentation dynamics of medium-sized clusters (1-2 nm) upon single photon multi-ionization is studied, by analyzing the momenta of small ionic fragments. The observed fragmentation pattern of the doubly- and triply-charged clusters reveals a spatial anisotropy of emission between frag
Mutation rates for X-linked recessive diseases have so far been estimated indirectly by postulating an equilibrium between the loss of defective genes caused by the low reproductive fitness of affected males and the gain resulting from new mutations. Here, for the first time, we directly estimate both the overall and sex-specific mutation rates for haemophilia B by detecting the gene defect of the
Objective: Advanced endovascular aortic repair can be used to treat patients with extensive and complex aortic disease who are at risk of spinal cord ischaemia. The aim of this study was to compare whether life satisfaction differs between patients with and without spinal cord ischaemia at mid-Term follow-up. Design: Nested case-control study. Patients: Among patients undergoing advanced endovascu
INTRODUCTION: Cachexia is a wasting condition that manifests in several types of cancer. The main characteristic of this condition is a profound loss of muscle mass.METHODS: By using a microarray system, expression of several hundred genes was screened in skeletal muscle of rats bearing a cachexia-inducing tumor, the AH-130 Yoshida ascites hepatoma. This model induced a strong decrease in muscle m
The invention relates to a method of 13C-MR detection using an imaging medium comprising hyperpolarised 13C-lactate and to an imaging medium containing hyperpolarised 13C1-lactate for use in said method.
BACKGROUND: Varus osteotomy of the proximal femur (VOPF) is one treatment option to prevent hip dislocation in children with cerebral palsy (CP). It is questioned whether the osteotomy should be performed in the displaced hip only, or if it should be performed bilaterally to prevent later displacement of the contralateral hip. CPUP is a register and healthcare programme for children with CP that w
Purpose: Fluoropyrimidine plus platinum (FP) is currently the standard treatment for esophageal cancer (EC). In recent years, taxane-based chemotherapy has also been used and has shown good efficacy in EC. This study aims to investigate the advantages of taxane-based over FP chemotherapy, as well as discuss its drawbacks, in the treatment of EC. Patients and methods: A literature search was done f
In the present work, heat transfer within gas turbine applications are investigated bothexperimentally and numerically. The main content concerns heat transfer and fluidflow over the pocket region and cooling of a turbine blade.A pocket cavity is generated at the junction part of the low pressure turbine (LPT) andthe outlet guide vane (OGV) in the rear part of a gas turbine engine. The heat transf
Background: The kidney injury molecule-1 (KIM-1) has previously been associated with kidney function in rodents and humans. Yet its role as a predictive marker for future decline in kidney function has remained less clear.Methods: At baseline (1991-1994), fasting plasma KIM-1 (p-KIM-1) was measured in 4739 participants of the population-based Malmö Diet and Cancer Study. Creatinine and cystatin C
Background: Circulating tumor cells (CTCs) carry independent prognostic information in patients with metastatic breast cancer (MBC) on different lines of therapy. Moreover, CTC clusters are suggested to add prognostic information to CTC enumeration alone but their significance is unknown in patients with newly diagnosed MBC. We aimed to evaluate whether longitudinal enumeration of circulating tumo
The development of multigene classifiers for cancer prognosis, treatment prediction, molecular subtypes or clinicopathological groups has been a cornerstone in transcriptomic analyses of human malignancies for nearly two decades. However, many reported classifiers are critically limited by different preprocessing needs like normalization and data centering. In response, a new breed of classifiers,
Coroplastic studies refer to the study of terracotta figurines mostly through an art history ap-proach, where types and classes are defined through stylistic and aesthetic considerations. Such an approach is highly subjective and is based on the knowledge of the researcher interacting with the subject material. Moreover, the lack of agreed upon criteria for classification and the lack of quantitat
Konferensbidrag, AESOP Annual Congress, Making Space for Hope, Gothenburg, July 2018
During the establishmen of an NGO Maritime Rescue Service (MRS)in the Lake Albert region in Uganda, the intelligence information management (IM) needs of the operation cere compared with earlier IM experiences of a combined peace keeping mission. This paper describes the MRS oparation IM needs. Furthermore, the Joint Command and Control Information Exchange Data Model (JC3IEDM) is introducea as th
An increasing number of people today live with chronic diseases that affect their quality of life and that of their families. Health professionals confirm this finding based on their clinical interventions targeting families of chronically ill patients. The aim of this study was to describe and evaluate these interventions. A systematic literature review was conducted, including previous reviews a
The level crossing method was used to measure the hyperfine structure of Bi 209 in the 6 p 2 ( 3 P 0 )6 d 2 D 3/2 and 6 p 2 ( 3 P 1 )7 s 4 P 3/2 levels of the Bi I spectrum. For the magnetic dipole and the electric quadrupole interaction constants a and b the following values were obtained: | a (6 p 2 ( 3 P 0 ) 6 d 2 D 3/2 )| = 128.0(0.6) g J /-0.79 MHz | b (6 p 2 ( 3 P 0 ) 6 d 2 D 3/2 )| = 58(4)
