Filetype
There is substantial genetic predisposition to bladder cancer (BC). Recently, blood pressure (BP) was positively associated with BC risk in men, but the potential interaction with genetic susceptibility for BC is unknown. We investigated a weighted genetic risk score (wGRS) of 18 BC genetic variants, BP, and their interaction, in relation to incident urothelial cancer (UC, n = 385) risk in 10,576
Hassles and uplifts, a concept used in measuring daily stress events, was applied to working mothers' everyday life. The aim was to explore the stability in working mothers' experiences in patterns of daily occupations, operationalized as hassles and uplifts, between the year 2000 (baseline) and the year 2005 (follow-up). Further, the intention was to reveal possible differences in the number, ori
Popular Abstract in Swedish Typ 2 Diabetes (T2D) räknas som en folksjukdom i Sverige vilket innebär att den är så vanlig att minst 4 % av befolkningen är drabbad. Förekomsten av diabetes ökar lavinartat över hela världen och man beräknar att så många som 300 miljoner människor har diabetes idag. Socker är en livsviktig energikälla, men lagom är bäst Socker i mat förs ut till blodet och används soType 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). The aim of this thesis has been to investigate functional and genetic events that
In this paper, a novel detection scheme for the monitoring of insect ecosystems is presented. Our method is based on the remote acquisition of passive sunlight scattering by two insect species. Procedures to identify rare events in remote dark-field spectroscopy are explained. We further demonstrate how to reduce the spectral representation, and how to discriminate between sexes, using a hierarchi
OBJECTIVES: To evaluate the long-term benefits of progressive resistance training in chronic stroke. DESIGN: A 4-year follow-up of a randomized controlled trial of progressive resistance training. SUBJECTS: Eighteen women and men (mean age 66 (standard deviation 4) from the original group of 24 post-stroke participants. METHODS: The training group (n = 11) had participated in supervised progres
Popular Abstract in Swedish Inledning I detta avhandlingsarbete studeras Mycoplasma pneumoniae (MP) och influensa virus ur olika perspektiv. Dessa två smittämnen orsakar båda årliga utbrott med luftvägsinfektioner som ibland blir omfattande epidemier. I båda fallen kan symptomen variera från lätta förkylningsbesvär till mycket svåra, ibland livshotande lunginflammationer. Infektion med MycoplasmaDiagnostic tests based on nucleic acid amplification have become available for Mycoplasma pneumoniae (MP) and influenza viruses. Here, an MP PCR test detected 100% of infections during the first three symptomatic weeks, whereas classical serology detected 21% week 1, 56% week 2, and 100% week 3. Positive PCR results were uncommon in healthy individuals. Levels of MP DNA were significantly higher i
The integrin CD103 is highly expressed at mucosal sites, but its role in mucosal immune regulation remains poorly understood. We have analyzed the functional role of CD103 in intestinal immune regulation using the T cell transfer model of colitis. Our results show no mandatory role for CD103 expression on T cells for either the development or CD4(+)CD25(+) regulatory T (T reg) cell-mediated contro
Based on the polarization and shape of the first symmetric Lamb mode at the zero-group velocity point (S1-ZGV), a novel approach for Impact-Echo thickness testing is proposed. In this new approach all three plate parameters (thickness, velocity and Poisson's ratio) are estimated from the same wave mode (S1-ZGV). A traditional approach based on a measurement of the longitudinal-and Rayleigh wave ve
Haemophilus influenzae is a Gram-negative human pathogen that resides in the upper respiratory tract. Encapsulated H. influenzae type b (Hib) and type f (Hif) are the most common serotypes associated with invasive disease. H. influenzae displays various strategies to circumvent the host innate immune response, including the bactericidal effect of the complement system. In this study, we identified
Aims: The roles of the diverse populations of micro-organisms responsible for biodegradation of organic matter to form methane and carbon dioxide are rudimentarily understood. To expand the knowledge on links between microbial communities and the rate limiting, hydrolytic stage of two-stage biogas production from energy crops, this study was performed. Methods and Results: The process performance.
The World Health Organization considers an aetiological classification of diabetes to be essential. The aim of this study was to evaluate whether HLA-DQB1 genotypes facilitate the classification of diabetes as compared with assessment of islet antibodies by investigating young adult diabetic patients. Blood samples were available at diagnosis for 1,872 (90%) of the 2,077 young adult patients (aged
This thesis consists of an introductory chapter followed by four separate papers. The papers deal with various aspects of human capital, ability and migration. Using the Swedish Military Enlistment test, the first paper, Ability and Rates of Return to Schooling ? making use of the Swedish Enlistment Battery Test, estimates the return to schooling for individuals belonging to different parts of th
A total of 300 gastric biopsy samples and 50 Helicobacter pylori isolates were collected from Ethiopian adult dyspeptic patients. The vacA and cagA genes were detected in 90 and 79% of biopsy specimens, respectively, and in 100 and 87% of clinical isolates, respectively. Both genes were detected in 84% of the gastric biopsy samples and in 87% of the clinical isolates. Among vacA genotypes, the s1/
Popular Abstract in Swedish Karl Landsteiner upptäckte blodgruppssystemet ABO och beskrev principen för den antigen-antikroppsreaktion som gäller än idag. För att utföra en säker blodtransfusion krävs det att individens ABO-blodgrupp är känd och därefter kan passande givarblod transfunderas. A- och B-generna ger upphov till enzymen A- respektive B-transferas. Blodgrupp O beror på olika defekter sABO is the most important blood group system in transfusion medicine and transplantation immunology. The ABO blood groups differ by the presence or absence of antigens on RBCs and antibodies in plasma. Accurate determination of ABO status is critical. Genomic typing can increase the precision of blood group determination in complicated cases, e.g. when variant expression of A or B antigen is encou
Psoriasis is a frequently occurring inflammatory skin disease characterized by thickened erythematous skin that is covered with silvery scales. It is a complex genetic disease with both heritable and environmental factors contributing to onset and severity. The CD18 hypomorphic PL/J mouse reveals reduced expression of the common chain of beta(2) integrins (CD11/CD18) and spontaneously develops a s
Popular Abstract in Swedish Avhandlingen beskriver och diskuterar de tidskrifter och böcker som muslimer i Sverige skrivit på svenska under 1900-talet. Framförallt gås innehållet i tidskriften Salaam - Islamisk Tidskrift (grundad 1986) igenom. Innehållet diskuteras i förhållande till hur islam har globaliserats de senaste tre decennierna. En slutsats är att Salaams skribenter har försökt att knytaThis dissertation focuses on written Islamic discourses in Swedish, especially the journal Salaam - Islamisk tidskrift. The journal first appeared in 1986 and is a part of the activities of Islamiska Informationsföreningen. From the beginning, Salaam has been edited by female converts to Islam in their twenties or early thirties. Female converts also account for a large number of the texts that ha
The article deals with how the Armenian genocide, perpetrated by the Young Turkish regime in the Ottoman Empire during the First World War, has been handled by Armenians, Turks and the international community from its pertetration to the present.
The reported rate of detection of Chlamydia pneumoniae DNA within atherosclerotic lesions by PCR varies between 0 and 100%. In this study, identical sets of coded experimental atheroma samples (n = 15) and spiked controls (n = 5) were analyzed by 16 test methods in nine centers by means of PCR. The positive controls were correctly identified to levels of 1, 0.1, and 0.01 inclusion bodies of C. pne
