Filetype
Background: Information and communication technology (ICT) has been proven to have effect in terms of providing alternative ways to deliver rehabilitation services. The intention with this paper is to serve as a foundation for discussions regarding the future development, design, and delivery of home-based rehabilitation, including ICT. Aim: To reflect on and discuss the possibilities and challeng
Background and Objectives: Early vascular aging determines a more rapid course of age-related arterial changes. It may be induced by a proinflammatory state, caused by hyperuricemia and metabolic syndrome and their interrelationship. However, the impact of serum uric acid (SUA) on early arterial stiffening and vascular function remains uncertain. Materials and Methods: A total of 696 participants
We study the rheological response of dense suspensions of elliptical particles, with an aspect ratio equal to 3, under oscillatory shear flows and imposed pressure by numerical simulations. Like for the isotropic particles, we find that the oscillatory shear flows respect the Cox-Merz rule at large oscillatory strains but differ at low strains, with a lower viscosity than the steady shear and high
Elevated maternal glucocorticoid levels during gestation can lead to phenotypic changes in offspring via maternal effects. Although such effects have traditionally been considered maladaptive, maternally derived glucocorticoids may adaptively prepare offspring for their future environment depending upon the correlation between maternal and offspring environments. Nevertheless, relatively few studi
The prevalence and character of political action has changed throughout the Global North, as individuals increasingly turn away from more conventional forms of political participation towards more everyday, continuous types of actions. In this study, I conceptualize one form of everyday political action as a politics of community. A politics of community describes a form of purposeful, collective
A chronicle describing the historical context and the development of ideas and experiments leading to the discovery of the back-bending phenomenon in rapidly rotating atomic nuclei some 50 years ago is presented. The moment of inertia of some atomic nuclei increases anomalously at a certain rotational frequency, revealing important clues to our understanding of nuclear structure. I highlight the d
This thesis deals with the dynamical processes in atoms and small molecules initiated by the absorption of ultrashort, coherent light pulses. The studied phenomena takeplace on the femtosecond (1 fs = 10−15 s) and attosecond (1 as = 10−18 s) timescales and critically depend on the properties of the light fields that drive them. Wework with infrared (IR) femtosecond laser pulses, which we manipulat
While many projects have demonstrated the potential of single Nature-based Solutions (NbS) to contribute to urban climate change adaptation, the challenge now lies in moving from demonstration projects to a full-scale deployment. The aim of this research is to assess the potential for a full-scale implementation of NbS in Malmö (Sweden), and the expected benefits and co-benefits. We developed six
Residual stress affects component performance, and the existence of pre-stress changes the residual stress of machined surfaces as well, emphasizing the importance of studying the evolution of residual stress in sequential cutting. This paper reports a numerical investigation of the machining-induced residual stress profile of sequential cuts for orthogonal cutting of AISI 304, considering the eff
INTRODUCTION: It is unclear how different proteinopathies (tau, transactive response DNA-binding protein 43 [TDP-43], amyloid β [Aβ], and α-synuclein) contribute to atrophy within medial temporal lobe (MTL) subregions in Alzheimer's disease (AD).METHODS: We utilized antemortem structural magnetic resonance imaging (MRI) data to measure MTL substructures and examined the relative contribution of ta
Numerical analyses (multidimensional scaling and Bk non-hierarchic cluster analysis) of wild populations of Silene dioica (L.) CIairv. from Scotland showed a complex pattern of variation, related partly to habitat and partly to geographic location. Subsets of characters- flower/capsule, seed, and vegetative characters- showed discordance, i.e. imperfectly correlated patterns of variation.Material
This article explores the role of religion in political transnationalism using the case of the Shi'a Iraqi diaspora since 2003. The article focuses on three areas that capture important trends in Shi'a transnationalism and their implications for transnational Shi'a identity politics. These include Shi'a diasporic politics, transnational Shi'a civic activism, and the cultural production of Iraqi Sh
Synthetic biology has established powerful tools to precisely control cell function. Engineering these systems to meet clinical requirements has enormous medical implications. Here, we adopted a clinically driven design process to build receptors for the autonomous control of therapeutic cells. We examined the function of key domains involved in regulated intramembrane proteolysis and showed that
This intervention will explain the life-worlds of Lebanon’s Shi‘is is distinct, shaped thoroughly by the community’s entanglement in a) the complex alliances and power-sharing arrangements characteristic of the Lebanese political system, b) geopolitical alignments and regionwide politics of hyper-sectarianisation, and c) the dynamics of protracted conflicts (not only in Lebanon and between Lebanon
The relationship between gender and mortality in nineteenth-century Europe has been highly debated. In particular, historians disagree about the manner and degree to which gender discrimination affected the mortality risk of the female population. This article contributes by examining the evidence of gendered mortality differences among children and adolescents in nineteenth-century Denmark. It ma
Numerous scholars have lately highlighted the importance of cities in the global response to climate change. However, we still have little systematic knowledge on the evolution of urban climate politics in the Global South. In particular, we lack empirical studies that examine how local climate actions arise in political-administrative systems of developing and emerging economies. Therefore, this
This protocol describes the design and use of CRISPRi-mediated transcriptional silencing in human iPSCs, for loss-of-function studies in brain development research. The protocol avoids single cell selection, thereby eliminating side effects of clonal expansion and sites of viral integration. We also describe a neural progenitor differentiation protocol and discuss the challenges of target-specific
Background and Objectives The neuropathologic changes underlying Alzheimer disease (AD) start before overt cognitive symptoms arise, but it is not well-known how they relate to the first subtle cognitive changes. The objective for this study was to examine the independent associations of the AD hallmarks β-amyloid (Aβ), tau, and neurodegeneration with different cognitive domains in cognitively uni
Background: Some degree of spontaneous recovery is usually observed after stroke. Experimental studies have provided information about molecular mechanisms underlying this recovery. However, the majority of pre-clinical stroke studies are performed in male rodents, and females are not well studied. This is a clear discrepancy when considering the clinical situation. Thus, it is important to includ
