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Background: Severe alpha-1-antitrypsin deficiency (AATD) is a genetic condition predisposing to chronic obstructive pulmonary disease (COPD) and liver disease. Its natural course is not well known. Our aim was to study the natural course of AATD by analyzing the clinical course in individuals with severe AATD identified by screening.Materials and Methods: Of the 1585 individuals included in the Sw
Research on younger patients with hip fractures is limited. This study adds knowledge on patient and injury characteristics, and DXA was investigated at the time of the fracture. Risk factors for osteoporosis and fractures were numerous among young patients, and osteoporosis was markedly more prevalent than in the general population.INTRODUCTION: Knowledge on younger patients with hip fractures is
Understanding the production mechanism of light (anti)nuclei is one of the key challenges of nuclear physics and has important consequences for astrophysics, since it provides an input for indirect dark-matter searches in space. In this paper, the latest results about the production of light (anti)nuclei in pp collisions at s = 13 TeV are presented, focusing on the comparison with the predictions
Background Creating new therapies often involves drug companies paying healthcare professionals and institutions for research and development (R&D) activities, including clinical trials. However, industry sponsorship can create conflicts of interests. We analysed approaches to drug company R&D payment disclosure in European countries and the distribution of R&D payments at the country
Background: Metronome cueing has been shown to reduce gait variability and thereby potentially reduce falls risk in individuals with Parkinson’s disease. It is unclear however, if metronome cueing has a similar effect in healthy older adults with a history of falls. Aim: To investigate whether a traditional and/or an adaptive metronome, based on an individual’s gait pattern, were effective in redu
Continuum modeling of granular media is made possible by the existence of a length scale at and above which grain-resolved properties can be meaningfully homogenized. Progress has been made in identifying such length scales relevant to local structural properties such as porosity. However, a systematic analysis of scales above which different mechanical properties can be homogenized has yet to eme
Hydrogen peroxide (H2O2) is for the first time measured and imaged in two-dimensions in an HCCI engine using photofragmentation laser-induced fluorescence (PF-LIF). Qualitatively, the experimental data agree with simulations.
I provide evidence on the impact of pre-primary school expansion on maternal labour supply in the context of South Africa. I draw on administrative data from the South African National Census in 2001 and 2011, and a Community Survey in 2007, to extract household information. My identification strategy exploits the staggered timing and intensity in the expansion of pre-primary school facilities acr
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is characterized by a progressive loss of dopaminergic neurons (DNs) in substantia nigra pars compact and accumulation of aggregated forms of the protein α-synuclein known as Lewy Bodies (LBs). LBs are present in surviving DNs and other regions of the central nervous system (CNS) in PD patients. PD patients also disp
1. Migratory species are particularly sensitive to climate change and face inadequate protection across their range. However, the behaviour of species and individual spatiotemporal variation in habitat use during their non-breeding periods are comparatively less well understood than breeding and migratory periods. 2. I combined five years’ worth of GPS tracking data on juvenile Caspian terns wit
A functioning charging infrastructure is crucial for achieving full-scale national electrification within the transport sector. The system is likely to consist of different charging technologies, all with the main objective of providing efficient energy replenishment services. Careful planning for the deployment of this infrastructure is of high importance. The consumer segments are diverse, each
This study establishes itself within the Social Accounting literature, particularly in the Corporate Social Responsibility (CSR) string in an effort to develop the knowledge of the current Swedish market, regarding gender equality. The objective of this thesis is to offer a thorough examination of the condition of sustainability reporting on gender equality across Swedish state-owned businesses.
”Architecture is the learned game, correct and magnificent, οf forms assembled in the light.” Le Corbusier. Nowadays, lighting covers a great portion of the total energy use of a building, almost 21%, while in most of the places, the quality of the existing lighting conditions is usually notably poor. In addition, lighting is responsible for 14% of all electricity demand in EU (CELMA, 2011) and 19
Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) har använts för att undersöka ålder och kemisk komposition av två texturellt skilda typer av monazit i leucosom och mesosom i polymetamorf aluminös migmatitgnejs vid Stensjöstrand, Halland. Dateringsresultat jämförs med tidigare publicerade zirkondateringar. Monazitkorn dokumenterades och undersöktes i tre tunnslip med hjälp aLaser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) has been utilised to investigate the age and chemical composition of two texturally different types of monazite in leucosome and mesosome of polymetamorphic aluminous migmatitic gneisses at Stensjöstrand, Halland. Results of radiometric dating are compared with previously published zircon dates. Monazite grains were documented
Effective and fair taxation is imperative for development and thus sustainable peace in post-conflict countries; yet there is a glaring paucity of generalizable research on the subject. Drawing on theories from Political Economy and Comparative Politics this thesis investigates how political veto powers affect these states’ ability to mobilize domestic resources. An integrated model of delayed pol
