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Popular Abstract in Swedish RB-GENEN SKYDDAR OSS MOT CANCER OCH STYR UTMOGNADEN AV BLODCELLER. Frisk och sjuk blodbildning: Varje dag bildas det ungefär ett tusen miljarder blodkroppar av olika sorter i vår benmärg. Varje dag, livet ut. Denna imponerande massproduktion av celler är livsnödvändig. Dom vita blodkropparna ser tex till att vi inte dukar under i infektioner, dom röda transporterar deThe aim of this study was to investigate the role of some tumor suppressor gene products (with emphasis on the retinoblastoma suppressor gene product) in the regulation of differentiation and proliferation in leukemic and normal hematopoietic cells. For this purpose, the expression of the tumor suppressor genes RB, p53 and p16 were artificially altered. Cells used were human leukemic cell lines an

The present contribution describes some simulations of the observation of binaries with GAIA. The results do not differ fundamentally from earlier estimates, e.g. in GAIA's Concepts and Technology Study Report (ESA-2000-SCI-4), but they are based on more realistic assumptions and much more extensive numerical work.

This paper reviews means for fatigue damage rates estimation using Laplace distributed multiaxial loads. The model is suitable for description of stresses containing transients of random amplitudes and locations. Explicit formulas for computing the expected value of rainflow damage index as a function of excess kurtosis are given for correlated loads. A Laplace model is used to describe variabilit

Abstract. The essay aims at integration of different concepts of meaning developed in semiotics, biology, and cognitive science, in a way that permits the formulation of issues involving evolution and development. The concept of sign in semiotics, just like the notion of representation in cognitive science, have either been used so broadly as to become almost meaningless, or they have been outrigh

In order to increase reuse, a number of product versions may be)", developed based on the same software platform. The platform must, however, be managed and updated according to new requirements if it should be reusable in a series of releases. This means that the platform is constantly changed during its lifecycle, and changes can result in degradation of the platform. In this paper, a measuremen

Popular Abstract in Swedish Shimazaki Toson (1872 - 1943) anses vara Japans främste företrädare för shizenshugi - en japansk form av fransk Naturalisme. Hans debut som romanförfattare skedde 1906 med Hakai - Löftesbrottet. Romanen anses allmänt vara en representant för kokuhaku shosetsu, eller en "bekännelseroman". Denna avhandling påvisar att författaren hade politiska ambitioner att påvisa diskrPublished in 1906, Hakai or The Broken Commandment in English, by Shimazaki Tôson, is generally considered the first novel in the genre of shizenshugi, a Japanese variation of French Naturalisme. Traditionally, the novel has been viewed as an example of kokuhaku shôsetsu, or “confessional novel” in that the protagonist “confesses” his origin as a member of Eta¾an autochtonous and despised minority

We performed high-resolution simulations of two stellar collisions relevant for stars in globular clusters. We considered one head-on collision and one off-axis collision between two 0.6-Msolar main-sequence stars. We show that a resolution of about 100000 particles is sufficient for most studies of the structure and evolution of blue stragglers. We demonstrate conclusively that collision products

Ultracold clouds of dimeric molecules can dissociate into quantum mechanically correlated constituent atoms that are either both bosons or both fermions. We theoretically model the dissociation of two-dimensional anisotropic molecular condensates for which this difference manifests as complementary geometric structures of the dissociated atoms. Atomic bosons are preferentially emitted along the lo

The expansion in the supply of energy services over the last couple of centuries has reduced the apparent importance of energy in economic growth despite energy being an essential production input. We demonstrate this by developing a simple extension of the Solow growth model, which we use to investigate 200 years of Swedish data. We find that the elasticity of substitution between a capital-labor

sustainability, contradiction, collapse, ecology, limits, history, global system

Popular Abstract in Swedish SVENSK SAMMANFATTNING Den kliniska effekten av läkemedel som administreras till näsa eller lunga beror på läkemedlets egenskaper och på dess lokala deposition. Depositionsstudier är därför värdefulla för att kunna karakterisera olika beredningar. Depositionen påverkas av partiklarnas storlek och hastighet, genom att stora partiklar med hög hastighet ger upphov till en hThe local deposition, pharmacokinetics, and systemic activity of inhaled and intranasal glucocorticosteroids in different formulations and devices(ICSs) has been investigated. After nasal administration of the ICS budesonide (Bud), the systemic availability (F) was found to be significantly higher from an aqueous pump spray and from the powder inhaler Turbuhaler, than from a pressurized metered do

With the general trends of the international development of codes, specifications and recommendations for a fire engineering design as a background, the rapidly expanding modelling capabilities are demonstrated and exemplified with respect to the fire growth in a compartment, the fully developed compartment fire, the reaction to fire of materials, the fire spread between buildings, and the fire be