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The feasibility of extracorporeal adsorption of 1.5-3 L plasma on protein A-Sepharose was investigated in six patients with advanced cancer. Anticoagulation with heparin was associated with respiratory distress syndrome in two patients, most likely caused by complement activation as indicated by a transient leukopenia during plasma reinfusion and appearance of C3 degradation products in the extrac
Previous research has expressed concerns about firms engaging less in basic research. We contribute to this debate by studying trends in the scientific publishing activities of firms located in Germany. Our results indicate that the firms’ aggregate volume of scientific publications stayed constant between 2008 and 2016. However, the number and share of publishing firms declined, and publication a
A growing number of human infections incriminate environmental bacteria that have evolved virulent mechanisms to resist amoebae and use them as a replicative niche. These bacteria are designated amoeba-resisting bacteria (ARB). Despite the isolation of these ARB in various human clinical samples, the possible source of infection remains undetermined in most cases. However, it is known that the ARB
The pharmacokinetics of total platinum (Pt) in plasma and cisplatin (CDDP)-DNA adducts in different cell types were described in ten patients with squamous-cell carcinoma of the head/neck or esophagus after their first cycle of chemotherapy containing a CDDP dose of 100 mg/m2. Nephrotoxicity was studied in terms of urinary excretion of marker proteins (protein HC, IgG, and albumin). Pharmacodynami
Individual migrants often fly detours when travelling between breeding and non-breeding sites, resulting in specific changes in flight directions along a migratory leg. Western European populations of the European Roller (Coracias garrulus), the only member of the roller family of birds to breed in Europe, differ substantially in their predicted flight directions, leading to different hypotheses b
Courtship displays are typically conspicuous, elaborate and composed of concomitant signals occurring in different sensory modalities. Although multimodal signals have received increasing attention over the past years, technical issues, in particular the lack of appropriate recording and analytical methods, have long restricted large-scale systematic study of their function. Here, we investigated
Confidentiality is a major determinant of the accessibility and acceptability of sexual and reproductive health care for adolescents. Previous research has revealed that Lithuanian adolescents lack confidence in guarantees of confidentiality in primary health care settings. This study aimed to assess the factors that affect general practitioners' decisions whether to respect confidentiality for Li
The use of dynamic movements on linear accelerators during irradiation have found a revised interest lately due to the integration of computers to control the linear accelerator. An example of this is the generation of fields that resemble ordinary wedge fields. These fields are produced by moving one of the collimator blocks during irradiation, i. e. dynamic wedges.A pencil beam based system with
During oxidative phosphorylation, the production of ATP is driven by the activity of several proton-pumping respiratory protein complexes. In plants, non-proton pumping type II NAD(P)H dehydrogenases are also present in the respiratory chain to oxidize cytosolic and matrix NAD(P)H. So far, it has not been fully clear what roles these enzymes play in the cellular metabolism. In Arabidopsis thalia
This paper discusses food security and the African food crisis. By means of data from a survey of over 3000 farm households in eight sub-Saharan countries, the authors conclude that food security requires a broad integration of smallholders in the market. Subsistence orientation does not promote food security, while seed fertilizer technology does. Market integration of maize producers seems to be
