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Background: Multiple risk scores claim to predict the probability of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy. It is unclear which scores have undergone external validation and are the most accurate. The aim of this study was to identify risk scores for POPF, and assess the clinical validity of these scores. Methods: Areas under receiving operator characteristic curve (A
Introduction and objectives: Bladder cancer is primarily a disease of older age and little is known about the differences between patients diagnosed with bladder cancer at a younger versus older age. Our objectives were to compare bladder cancer specific survival in patients aged <50 versus those aged 50–70 at time of diagnosis. Materials and methods: The Swedish bladder cancer database provided d
The LIM-homeodomain transcription factor Islet-1 (Isl1) has been widely used as a marker of different subtypes of neurons in the developing and mature retina of vertebrates. During retinal neurogenesis, early Isl1 expression is detected in the nuclei of neuroblasts that give rise to ganglion, amacrine, bipolar, and horizontal cells. In the mature retina, Isl1 expression is restricted to the nuclei
BACKGROUND: Preoperative radiological assessment of meningioma characteristics is of value for pre- and post-operative patient management, counselling, and surgical approach.PURPOSE: To investigate whether tensor-valued diffusion MRI can add to the preoperative prediction of meningioma consistency, grade and type.MATERIALS AND METHODS: 30 patients with intracranial meningiomas (22 WHO grade I, 8 W
AimThe aim of this study was to investigate if prophylactic treatment in severe haemophilia impact on bone mineral densisty (BMD) in adults with haemophilia A/B.MethodsSubjects with haemophilia (n = 120) underwent bone-density measurement and clinical data was collected. BMD in subjects with severe haemophilia on high-dose prophylaxis (n = 41) was compared to BMD in subjects with mild haemophilia
Iran is mainly located in the arid and semiarid climate zone and seriously affected by desertification. This is a severe environmental problem, which results in a persistent loss of ecosys-tem services that are fundamental to sustaining life. Process understanding of this phenomenon through the evaluation of important drivers is, however, a challenging work. The main purpose of this study was to p
The “cultural turn” in memory studies acknowledges that collective memory has a distinctive social aspect reflected in the manner in which it is communicated orally from one individual or generation to another. However, the point of departure is the emphasis on the need to account for the fact that memory is, in equal measure, shaped and mediated by tangible channels such as texts, images, objects
Background Breathlessness is prevalent in severe disease and consists of different dimensions that can be measured using the Multidimensional Dyspnea Profile (MDP) and Dyspnea-12 (D-12). We aimed to evaluate the feasibility of MDP and D-12 over telephone interviews in oxygen-dependent patients, compared with other patient-reported outcomes (modified Medical Research Council (mMRC) and Chronic Obst
Parental influence over children’s status attainment has historically been argued to be key. However, the cross-sibling influence has been scarcely studied for historical periods and for steam family societies, being the most long-lasting relationship across individuals’ lives once childhood was surpassed. We investigate how intra-generational family relationships determine the social destiny of s
The growing understanding of the increased frequency and severity of extreme weather events due to climate change demands action. Locally, measures to adapt must be taken without knowing exactly what will happen, where it will happen or what the consequences will be. To meet this need, a number of decision support tools have been developed and this article investigates how municipalities can imple
Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm that follows a heterogeneous clinical course. Recurrent mutations have been described, but their applicability in the clinical setting is currently limited. The main reasons are challenges in the sequencing of DNA retrieved from formalin-fixed tissue commonly used for tissue collection in clinical biobanks. In this study, we sequenced 77
Sweden’s Art and Music Schools (SAMS) have assumed some responsibility for facilitating refugee children’s social inclusion. This article investigates how the inclusion of refugee children in SAMS is introduced by leaders as well as how the theme is constructed and addressed as a topic in policy documents (related to the national policy process for SAMS). Two data sets constitute the empirical bas
Convective heat transfer of aviation kerosene at supercritical pressures in a vertical upward tube of diameter 1.8 mm was numerically studied using RNG k-ε turbulence model with enhanced wall treatment. The thermo-physical and transport properties of the China RP-3 kerosene at various temperatures were obtained by a 10-species surrogate and the NIST Supertrapp software. The grid independence was f
Background: Both anti-viral and anti-inflammatory bronchial effects are warranted to treat viral infections in asthma. We sought to investigate if imiquimod, a TLR7 agonist, exhibits such dual actions in ex vivo cultured human bronchial epithelial cells (HBECs), targets for SARS-CoV-2 infectivity. Objective: To investigate bronchial epithelial effects of imiquimod of potential importance for anti-
This study aimed to experimentally examine how riverbed drying and different rates of water level reduction influenced the vertical movement of amphipods of various sizes into different subsurface sediment compositions. Using sediment columns (mesocosms) filled with different sized transparent substrates, we explored how varying speeds of drawdown affected vertical movement and stranding of indivi
This article explores how the Swedish historian Birgitta Odén (1921–2016) sought to launch an interdisciplinary environmental research program in the late 1960s. Odén’s objective was to make history useful for political decision making, yet the research program never received any substantial funding. This article argues that the analytical concept of circulation of knowledge offers a fruitful way
