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Identification of risk factors for fractures is important for improving public health. We aimed to identify which factors related to physical activity and psychosocial situation were associated with incident fractures among 30,446 middle-aged women and men, followed from 1991-1996 to 2016, in a prospective population-based cohort study. The association between the baseline variables and first inci
Is the oncogene MYC upregulated or hyperactive? In the majority of human cancers, finding agents that target c-MYC has proved difficult. Here we report specific bacterial effector molecules that inhibit cellular MYC (c-MYC) in human cells. We show that uropathogenic Escherichia coli (UPEC) degrade the c-MYC protein and attenuate MYC expression in both human cells and animal tissues. c-MYC protein
Background: The goal of postnatal care is to provide the highest possible quality of care and medical safety with the least possible intervention in order to optimize health and wellbeing of the new family. The aim of the study was to describe mothers´ experiences in relation to a new postnatal home-based model of midwifery care. Methods: The current study uses a cross-sectional mixed method desig
Tick-borne encephalitis (TBE) is a widespread viral infection of the central nervous system with increasing incidence in Europe and northern Asia. Post-infectious sequelae are frequent, and patients with TBE commonly experience long-term fatigue and subjective sleep disturbances. Obstructive sleep apnea (OSA) may be a contributing factor, and objective sleep studies with polysomnography (PSG) are
The integration of ecosystem service (ES) knowledge into decision-making processes is increasingly endorsed by various policies and initiatives, with spatial planning targeted as one of the most relevant fields. Learning and feeding back from existing experiences is therefore a fundamental step to ensure appropriate and useful support by ES science. This paper aims to gather and critically analyse
Med anledning av oroligheter i Rinkeby tunnelbanestation har företrädare för Polisen, MTR Nordic, Rinkeby-Kista Stadsdelsförvaltning, FastPartner, Securitas, Säkerhet Ordningsbevakning SOB (SOB) och Trygghetscentralen (TC) arbetat utifrån Brå:s samverkansmodell för lokalt brottsförebyggande arbete.Denna utvärdering undersöker om samverkansmodellen varit framgångsrik, om de lokala brottsförebyggand
This paper aims to identify and review new and unproven emergency department (ED) methods for improved evaluation in cases of suspected acute coronary syndrome (ACS). Systematic news coverage through PubMed from 2000 to 2006 identified papers on new methods for ED assessment of patients with suspected ACS. Articles found described decision support models, new ECG methods, new biomarkers and point-
We compare abundance ratio trends in a sample of ∼11,000 Milky Way bulge stars (R GC < 3 kpc) from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) to those of APOGEE stars in the Galactic disk (5 kpc < R GC < 11 kpc). We divide each sample into low-Ia (high-[Mg/Fe]) and high-Ia (low-[Mg/Fe]) populations, and in each population, we examine the median trends of [X/Mg] versus [Mg/
The benefit of surgery in high-grade gastroenteropancreatic neuroendocrine neoplasms (GEP NEN) and mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) is uncertain. The present study aimed to investigate outcomes after tumour surgery in patients with high-grade (Ki-67 > 20%) GEP NEN or MiNEN stage I-III or stage IV. We analysed data from patients treated in the period 2007-2015 at eight Nord
We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the World Health Organization European Region available until 10 July 2020. We highlight the importance of real-time sequencing and data
This paper presents the first measurements of the charge independent (CI) and charge dependent (CD) two-particle transverse momentum correlators G2CI and G2CD in Pb–Pb collisions at √SNN=2.76 TeV by the ALICE collaboration. The two-particle transverse momentum correlator G2 was introduced as a measure of the momentum current transfer between neighboring system cells. The correlators are measure
γ-CoV2O6 is a quasi-one-dimensional spin-3/2 magnet that possesses two distinct magnetic orders at low temperatures with propagation vectors k1=(½,0,0) and k2=(¼ + δh, δk, - ¼ + δl), respectively. Here we use muon spin relaxation and rotation to reveal the thermodynamics of the magnetic phase separation in this compound. In the paramagnetic (PM) region, short-range correlated spin clusters emerge
The incidence of type 1 diabetes in children is growing and optimal treatment is needed to prevent or delay complications. Insulin degludec is a new basal insulin with ultra-long effect. However, there are few published studies in children and adolescents. The first aim was to compare HbA1c levels in children and adolescents who received degludec from onset, to age/gender matched controls with oth
Aims To establish normative values of vibration perception thresholds (VPTs), using multi-frequency vibrometry at finger pulps and at metatarsal heads of the foot in healthy adults. We also aimed to investigate factors that could potentially affect VPTs such as age, sex, height, weight, foot- or handedness and skin temperature. Methods VPTs were examined in 924 healthy and randomly selected subjec
This chapter provides a reassessment of the waste ‘crises’ in the so-called Land of Fires in Italy and highlights the contribution of local social mobilizations in advancing environmental justice and sustainability concerns. It is based on the long term collaboration between a social scientist and two activists, and it draws from a dialogue of academic and activist knowledge in the tradition of En
Information and communication technologies (ICTs) are located at the center of international development and considered vital for the progress of the current sustainable development goals. ICTs are embedded in cultural structures and social norms, which provide both possibilities and challenges to the people working with technologies such as mobile phones. Drawing upon theories and methodologies o
For the perennial herb G. fastigiata on the Baltic island of Oland, there were significant correlations between electrophoretic variation at the PGI-2 locus and fine-scale gradients of compositional change in the limestone grassland plant communities occupied by G. fastigiata. Variation at the AAT-3 and IDH loci and in seed phenotype showed no significant correlations with plant community composit
Experimental methods to study the breakup frequency in industrial devices are increasingly important. Since industrial production-scale devices are often inaccessible to single-drop experiments, breakup frequencies for these devices can only be studied with “global methods”; i.e., breakup frequency estimated from analyzing emulsification-experiment data. However, how much can be said about th
What happens to dominant narratives and settled self-images of so-called peace nations when experiencing actual combat in out-of-area military missions? This question arises when studying the contemporary international engagement of small states that previously have mostly been engaged in peacekeeping with limited mandates and non-use of force restrictions. As today's international missions have a
This article presents a new and previously unchartered dataset on roll call votes for all 28 member states in the Council of the EU between 2010 and 2019 and studies the effects of politicisation on governments' oppositional voting in the different policy areas. We contribute to the literature with two main findings. First, our study provides strong evidence for bottom-up politicisation, where Eur
