Filetype
An early age at first full-term birth is associated with a reduction in the subsequent development of breast cancer among women in the general population. A similar effect has not yet been reported among women who carry an inherited BRCA1 or BRCA2 mutation. We conducted a matched case–control study on 1816 pairs of women with a BRCA1 (n = 1405) or BRCA2 (n = 411) mutation in an attempt to elucidat
Experimental research was conducted to reveal the effects of nanofluids on heat transfer performance in a double-tube heat exchanger. With nanoparticle weight fraction of 0.5-2.0% and Reynolds number of 4500-14500, the flow resistance and heat transfer were analyzed by using six nanofluids, i.e., CuO-water, Al2O3-water, Fe3O4-water, ZnO-water, SiC-water, SiO2-water nanofluids. Results show that Si
Congenital stationary night blindness (CSNB) is a group of rare, mainly stationary disorders of the retina, resulting from dysfunction of several specific and essential visual processing mechanisms. The inheritance is often recessive and as such, CSNB may be more common among populations with a high degree of consanguinity. Here, we present a topic update and a review of the clinical and molecular
A novel kind of regenerative cooling channel, a so-called nested channel, is proposed to further reduce the combustion chamber wall temperature of a scramjet. The supercritical n-decane heat transfer in the horizontal up-channel and horizontal down-channel with different flow directions are numerically investigated. The temperature distribution, flow field, and vortex structure are presented to di
One of the benefits of cooperative hunting may be that predators can subdue larger prey. In spiders, cooperative, social species can capture prey many times larger than an individual predator. However, we propose that cooperative prey capture does not have to be associated with larger caught prey per se, but with an increase in the ratio of prey to predator body size. This can be achieved either b
The Quaternary East Asian summer rainfall evolution reconstructed with the Chinese speleothem δ18O records shows the consistency throughout the region of East Asia, and has long been considered equivalent to the monsoon intensity. Its variation and teleconnection with global climate were usually interpreted by the meridional shift of the intertropical convergence zone (ITCZ). However, many other p
Capsule endoscopy (CE) is indicated as a first-line clinical examination for the detection of small-bowel pathology, and there is an ever-growing drive for it to become a method for the screening of the entire gastrointestinal tract (GI). Although CE's main function is diagnosis, the research for therapeutic capabilities has intensified to make therapeutic capsule endoscopy (TCE) a target within r
In this article, we argue that basic social policy concepts can fertilise the discussion on active labour market policy (ALMP). During the last decades, research on ALMP has become a flourishing field. This is an overall positive development. However, the development tends to fractionate the wider picture of social policy and distance the discussion from social policy seen as a multifold set of go
OBJECTIVE: It was shown by genomic profiling that despite no detectable chromosomal abnormalities a proportion of children with pre-B acute lymphoblastic leukemia harbors copy number alterations (CNA) of genes playing role in B-cell development and function. The aim of the study was to determine the frequency of CNA in pediatric acute lymphoblastic leukemia and correlate these findings with clinic
Maintaining soil health is integral to agricultural production, and the archaeological record contains multiple lines of palaeoclimatic and palaeoenvironmental proxy evidence that can contribute to the understanding and analysis of long-term trajectories of change that are key for contextualizing 21st century global environmental challenges. Soil is a capital resource and its nutrient balance is m
Cross-reactivities among tumor-associated antigens of rat mammary fibroadenomas and among these fribroadenomas and a rat mammary carcinoma were investigated by in vitro techniques. Lymphocytes from five female W/Fu rats bearing mammary fibroadenomas were found to share a common reactivity against fibroadenoma target cells, as demonstrated by lymphocyte cytotoxicity tests on iododeoxyuridine-l25I-l
Antiarrhythmic effects of melatonin have been demonstrated ex vivo and in rodent models, but its action in a clinically relevant large mammalian model remains largely unknown. Objectives of the present study were to evaluate electrophysiological and antiarrhythmic effects of melatonin in a porcine model of acute myocardial infarction. Myocardial ischemia was induced by 40-min coronary occlusion in
Alternative ways for increased appetite control are today widely sought for due to the growing global health issues connected to obesity. In in vivo studies, oat has been proven an attractive candidate for inducing satiety. Oat is rich in polar lipids, of which the galactolipids are especially interesting, and a hypothesis is that these lipids play an important role for the ileal brake mechanism.
