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Solar influences on climate variability are one of the most controversially discussed topics in climate research. We analyze solar forcing of flood frequency in central Europe during spring and summer on interannual to multi-centennial timescales, integrating daily discharge data of the River Ammer (southern Germany) back to AD1926 (∼solar cycles 16-23) and the 5500-year flood layer record from va
The close relationship between young children’s living conditions and their healthlater in life is well documented and a safe and healthy environment during earlychildhood promotes cognitive functions and social development during the wholelifespan. Becoming a parent is a major life transition and it is sometimes described as a stressful and vulnerable time involving changes to lifestyle and routi
Hypothermia diminishes the ischemia-induced protein kinase C (PKC) translocation and inhibition, and also reduces transmitter release during ischemia. To study the role of PKC in the mechanism of glutamate release during ischemia, we measured extracellular glutamate levels in the striatum with the microdialysis technique, in the presence and absence in the dialysate of the PKC activator 4β-phorbol
Combining data from spontaneous face-to-face conversations in the London-Lund Corpus (LLC) of spoken British English and a laboratory experiment, this paper analyses the dynamic nature of I think constructions in dialogue. We make use of the functional category of ENGAGEMENT in APPRAISAL theory as an analytical tool (Martin & White, 2005). More precisely, we examine whether I think constructio
Factor VIII (F.VIII) and von Willebrand factor (VWF):Ag data collected by eight laboratories on a total of 336 obligatory carriers of hemophilia A and 137 normal women were used to answer several questions concerning the construction of linear discriminants for carrier detection. It was found: that a "universal" linear discriminant can be constructed which is suitable for use in all laboratories a
This article examines socioeconomic mobility across three generations in Sweden from 1815 and until 2011. Using longitudinal micro-level data from the Scanian Economic-Demographic Database (SEDD), we examine the transmission of socio-economic status along three different dimensions; social class (HISCLASS), occupational status (HISCAM), and earnings. We demonstrate an association between grandfath
The aim of this study was to ascertain how many of the sporadic cases of severe Haemophilia A in Sweden are due to recent mutation, and establish its origin. DNA analysis was performed in 18 randomly selected families with a sporadic case of severe haemophilia A. Restriction fragment length polymorphism (RFLP) patterns were investigated, two intragenic (Bc1 I, Xba I/Kpn I) and two extragenic (DX 1
The electrophysiological effects of pentisomide upon the intact human heart were evaluated using programmed stimulation and recording of intracardiac monophasic action potentials (MAP) in 17 patients with various ventricular arrhythmias. After i.v. administration of pentisomide, 85-135 mg, the atrial-His interval increased by 8 +/- 12 ms (p less than 0.05) during sinus rhythm and by 13 +/- 21 ms (
The pilot-control globe valve (PCGV) is a novel globe valve with a piston-type valve core and a small pilot valve. It can utilize a pressure difference to control the state of the main valve by the pilot valve. In this paper, a mathematical model of PCGV is established and a computational fluid dynamics (CFD) method is used to numerically simulate its flow and cavitation characteristics. Analysis
Multivariate versions of the Kronecker theorem in the continuous multivariate setting has recently been published, that characterize the generating functions that give rise to finite rank multidimensional Hankel and Toeplitz type operators defined on general domains. In this paper we study how the additional assumption of positive semi-definite affects the characterization of the corresponding gen
This article explores the role of informality among Uzbek construction workers in Russia. We start from a relationship that is based on economic reward and common interests and go on to explore the non-economic components of this relationship. Economically, the workers entrust their supervisor and agree to work for him for a given amount of money. However, this decision is also embedded in a non-e
BACKGROUND: There is a wealth of evidence detailing gray matter degeneration and loss of cognitive function over time in individuals with Huntington's disease (HD). Efforts to attenuate disease-related brain and cognitive changes have been unsuccessful to date. Multidisciplinary rehabilitation, comprising motor and cognitive intervention, has been shown to positively impact on functional capacity,
INTRODUCTION: Although estrogen and progesterone play a key role in normal mammary development and in breast cancer, the potential for proliferation and lineage differentiation as well as origin of cells that express the estrogen receptor (ER) in normal breast epithelium are not known. Some evidence suggests that normal human mammary stem/progenitor cells are ER-, but the identity of these cells a
Large Eddy Simulation (LES) was employed to investigate the fuel/oxidizer mixing process in an ethylene fueled scramjet combustor with a rearwall-expansion cavity. The numerical solver was first validated for an experimental flow, the DLR strut-based scramjet combustor case. Shock wave structures and wall-pressure distribution from the numerical simulations were compared with experimental data and
This paper explores how noblemen expressed themselves in late-medieval Scandinavian castles, in the buildings and in the landscape. The focus is on decorated stone tablets with coats of arms and memorial texts found on the castle walls, but the landscape setting of the castles is also discussed. The examples considered here are Glimmingehus in Scania, in present-day southern Sweden, and Olofsborg
We used the in vitro regenerating frog sciatic nerve to look for effects of insulin and insulin-like growth factors I and II (IGF-I, IGF-II) on regeneration of sensory axons and on injury induced support cell proliferation in the outgrowth region. In nerves cultured for 11 days, a physiological dose (10 ng/ml, ≈ nM) of insulin or IGF-II increased ganglionic protein synthesis (by 20% and 50%, respe
The involvement of cytosolic phospholipase A2 (cPLA2) in apoptosis of adult mouse superior cervical and dorsal root ganglia neurons has been investigated by the use of immunohistochemistry for cPLA2 and DNA nick-end labeling for apoptotic cells, respectively, cPLA2 immunoreactivity was strongly upregulated in neurons of both preparations during in vitro culturing. By double labeling it was unequiv
Functional recovery is markedly restricted following traumatic brain injury (TBI), partly due to myelin-associated inhibitors including Nogo-A, myelin-associated glycoprotein (MAG) and oligodendrocyte myelin glycoprotein (OMgp), that all bind to the Nogo-66 receptor-1 (NgR1). In previous studies, pharmacological neutralization of both Nogo-A and MAG improved outcome following TBI in the rat, and n
