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The family of proteins called galectins, are a group of carbohydrate-binding proteins. This allows them to take part in cell signalling by binding to glycoproteins on cell surfaces. Galectin-9 has been identified as a TIM3 ligand. TIM3 is a protein found on T-cells, which are used by the immune system to destroy for example cancer cells. When galectin-9 binds TIM3 it starts a reaction chain which
