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Introduction: The MP2RAGE technique has become popular for structural MRI at ultra-high fields. The core idea behind MP2RAGE is to reduce the influence of flip angle inhomogeneity (B +), proton density and T2* by calculating the regularized signed ratio of two complex MP-RAGE images acquired at different inversion times (TI) within the cycle. From this MP2RAGE signal, the underlying T1 relaxation
