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Southern Kazakhstan, particularly the Zhambyl Region, is facing increasing groundwater stress due to climate change, degradation of irrigation infrastructure, and unsustainable water use. Despite substantial renewable groundwater reserves (8.33 km3/year), irrigation still relies on ephemeral surface flow. This study delineates priority zones for Managed Aquifer Recharge (MAR) using a GIS-based Mul
Could an even larger push for women empowerment be a viable development strategy for developing countries? A large literature relates the bargaining power of women to improved health and education of their children (Majlesi, 2015; Qian, 2008; Bobonis, 2009; Duflo, 2003; Lundberg, Pollak and Wales, 1997). However, it remains a challenge to find a good proxy for bargaining power that truly reflects
Input-output analyses have gained relevance in studies examining the value added distribution along globally fragmented value chains. However, their reliability to reflect true value added contributions has been challenged by biases identified by Nomaler & Verspagen (2014). In order to extend their analysis with an empirical component, we construct hypothetical input-output tables representing
In this episode we talk to Georgia De Leeuw about her research on mining, green steel and the comfort alignment with extractivism in in the Swedish north, or indigenous Sápmi. Her PhD dissertation deals with Swedish extractivism in Sápmi through the examples of a planned iron ore mine in Gállok/Kallak and the hydrogen-based steel transition. The main aim is to understand the trust that is placed i
Phytoglobins (Pgbs) are plant hemoglobin-like proteins with key roles in nitric oxide (NO) scavenging, oxygen sensing, and hypoxic stress responses. Their typical hexacoordination results in unusually high affinities for gaseous ligands such as NO and carbon monoxide (CO), complicating measurement using conventional methods. Standard assays often require large sample volumes and lack sensitivity f
Introduction: Taxonomic instability within the dynamic gut microbiome of very preterm infants can be associated with various adverse outcomes. This longitudinal study was designed to follow the trajectory of microbiome composition and abundance in a cohort of probiotic supplemented very preterm infants with and without sepsis. Methods: Stool samples (n = 180) from probiotic-supplemented participan
Studies in temperate systems provide evidence that the abundance of arbuscular mycorrhizal fungal (AMF) depends on soil nutrient availability, which is mainly explained in the context of resource stoichiometry and differential plant biomass allocation. We applied this concept to an understudied ecosystem - tropical montane forest - analyzing root and AMF abundance along an elevational gradient wit
We describe a method to estimate child mortality using linked IPUMS full-count census data for the decades following the 1850, 1860, 1870, 1900, 1910, 1920, and 1930 censuses. We compare the estimates to several external sources and conclude that the method represents a viable way to estimate and model child mortality at individual and aggregate levels over the course of the mortality transition.
Water resource recovery facilities face challenges with increasingly stringent effluent demands, complexity and demand for capacity increasing investments. Emerging technologies such as digital twins could alleviate these problems but require high frequency influent data. This work presents a method for utilising measurements in the primary clarifier effluent with a model of the processes between
Aim: In uncertain clinical situations, such as assessing the risk of exacerbation of apical periodontitis in root- filled teeth, un-dergraduate students can benefit from being trained to reflect. This study aimed to explore how students specifically reflectedon clinical experiences in relation to uncertainty when assessing a case involving a root- filled tooth with apical periodontitis.Methodolo
Melanoma brain metastases (MBM) exhibit extensive intertumor and intratumor heterogeneity (ITH), driven by a complex tumor microenvironment. The aim of this study was to perform a detailed analysis of individual MBM patient tumors using a multiomics approach, integrating spatial transcriptomics with multi-region bulk exome, proteome, and transcriptome profiling for a small group of four patient sa
Background: Gut dysbiosis and gut-brain-axis involvement in people with Parkinson's disease (PwP) support the use of gut-microbiota-modulating interventions. Probiotics may help manage constipation in PwP; however, mechanisms underpinning additional beneficial properties are unknown. Objective: The aim was evaluating the effects of a probiotic (Lacticaseibacillus rhamnosus, Lactobacillus acidophil
OBJECTIVES: Ultra-high dose rate irradiation (UHDR) has been shown to spare normal tissue in various model systems. This study evaluates its potential to sterilize cancer cells using spheroid tumor models.METHODS: Spheroids from glioblastoma (U87), hypopharyngeal squamous cell carcinoma (two sizes, FaDusmall and FaDularge) and breast adenocarcinoma (T47D) cells were irradiated with electron beams
Despite substantial contextual differences between the West and China, systems approaches have been recognized as essential for addressing complex and dynamic management challenges, particularly within the field of innovation. However, most previous studies are rooted in traditional cybernetics within the framework of first-order science, which is characterized by linear processes and stable eleme
This study examines the impact of grammatical gender on memory recall among simultaneous bilinguals with two three-gendered languages (Ukrainian and Russian). Ukrainian-Russian bilinguals and English monolingual controls were tested on their ability to remember names assigned to objects with either matching or mismatching grammatical genders across their two languages. Results showed that bilingua
Axonal injuries commonly contribute to poor functional outcomes following traumatic brain injury (TBI). To assess cerebral blood flow (CBF) and energy metabolic disturbances in a TBI model of widespread axonal injury, we exposed 105 adult mice to the central (midline) fluid percussion injury (cFPI) diffuse TBI model, or sham injury, and used 9.4 T magnetic resonance (MR) arterial spin labeling (AS
Introduction: Proactive and easily accessible interventions are needed to support people with long-term health conditions who experience limitations in activities of everyday life. However, there is a lack of interventions that promote self-management skills that prevent deterioration and improve health. The internet-based programme 'Strategies for Empowering Activities in Everyday Life' (SEE) sup
This study investigates how national policies in nine Western Pacific countries—China, Japan, South Korea, Australia, New Zealand, Singapore, Malaysia, Vietnam, and Cambodia—promote healthy ageing through multi-sector collaboration. The objective is to identify common patterns and country-specific features in the governance and organization of collaborative efforts. Using comparative case study an
Purpose: There are limited data to show how sex impacts the early clinical course of patients with Hirschsprung disease (HSCR). This study aimed to explore potential sex related disparities in the preoperative, surgical, and early postoperative course of HSCR patients. Methods: This retrospective study analyzed data of HSCR patients who underwent pull-through surgery at pediatric surgery centers i
Introduction: Anal squamous cell carcinoma (ASCC) is primarily treated with chemoradiotherapy (CRT), but surgery can be curative following treatment failure. The treatment of ASCC was centralised in Sweden in 2017. This study aims to describe the characteristics and outcomes of surgery for ASCC nationally, focusing on short-term morbidity and mortality. Materials and Methods: All patients with ASC
