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In the face of climate change, today’s young people need to balance the challenges of being active and maintaining mental health. This study investigated climate resilience, meaning patterns of climate engagement and mental health among adolescents. Using latent profile analysis, we identified three profiles in a sample of N=603 Swedish adolescents: climate-resilient (17%, active and not impaired)
When violence against a child is reported to authorities, it is crucial that its severity is communicated effectively and evaluated accurately by professionals. This study, conducted in two phases, investigated perceptual differences in calibration and accuracy regarding psychological and physical violence against children among parents, social workers, and laypeople. In Phase 1, parents who had w
Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperativ
Background: The prognostic benefit of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in stable coronary artery disease (CAD) remains uncertain. Objectives: To evaluate long-term survival following CTO PCI compared with medical therapy (MT) using target trial emulation and a nationwide real-world registry. Methods: We included 7813 patients with stable CAD and a document
Acute postoperative pain remains common despite advances in surgical techniques and enhanced recovery protocols, suggesting that patient-specific factors and individualised approaches may be key to improving outcomes. Real-time intraoperative nociceptive monitoring has emerged as a potential tool to guide analgesia and predict postoperative pain bur their role in an individualised anaesthesia fram
Introduction: The transition from pediatric to adult healthcare represents a crucial period for adolescents and youth living with HIV. When this healthcare transition is not properly managed, it can result in negative outcomes such as loss to follow-up (LTFU), increased morbidity, and mortality. Therefore, it is essential to estimate the incidence rate and identify predictors of loss to follow-up
Context: Pollen-mediated gene flow is crucial for ecological and evolutionary processes and understanding its disruption by anthropogenic disturbances is essential for conservation. Objectives: In this study, we developed landscape connectivity metrics that incorporated hummingbird movement behaviour to assess how structural (amount and configuration) and functional (species-specific behavioural r
Childhood stunting (height‑for‑age z‑score < −2) remains a global public health challenge, and national averages often mask subnational clustering and spatial heterogeneity of underlying determinants. Across four papers, this thesis integrates geocoded household data with gridded geospatial surfaces from nationally representative survey data to map stunting hotspots, quantify spatially varying and
High precision single-differential W±-boson production cross-sections as a function of electron or muon transverse momentum pT or their pseudorapity η, as well as double-differential cross-sections as functions of these variables, are measured in proton–proton collisions at centre-of-mass energies s=5.02 TeV and 13 TeV. The W-boson charge asymmetry as a function of lepton η is also measured. The d
This paper examines the evolving role of universities in transferring and developing knowledge to foster transformative Science, Technology, and Innovation (STI) policy amid significant shifts in economic development landscapes. With a rising focus on geopolitics, defense, resilience, and disruptive technologies, universities are increasingly expected to e
Objectives: To examine powered mobility learning in children with spinal muscular atrophy (SMA) type I, involving families and evaluating goal attainment through the use of small, modified electric toy cars in the children’s natural environments. Design: Single-blind pilot intervention study derived from an originally planned wait-list randomized controlled trial. This report includes only the imm
Background: Breast cancer polygenic risk scores (PRS) and traditional risk models (e.g., the Gail model [Gail]) are known to contribute largely independent information, but it is unclear how the overlap varies by ancestry, age, disease type (invasive breast cancer, DCIS), and risk threshold. Methods: In a retrospective case–control study, we evaluated risk prediction performance in 180,398 women (
We study a simple extension of the Standard Model featuring a dark sector with an ultralight pseudo-Nambu-Goldstone boson as a dark matter candidate. We focus on the mass range O(10-20-10-10) eV, relevant for strong gravity applications, and explore its production and evolution in the early Universe. The model is formulated in such a way that dark matter does not couple directly to photons or othe
Challenges from infections caused by biofilms and antimicrobial resistance highlight the need for novel antimicrobials that work in conjunction with antibiotics and minimize resistance risk. In this study we investigated the composite effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells), a human milk protein-lipid complex and amoxicillin on microbial ecology using an ex vivo oral
Importance: There is uncertainty about whether prolonged infusions of β-lactam antibiotics improve clinically important outcomes in critically ill adults with sepsis or septic shock. Objective: To determine whether prolonged β-lactam antibiotic infusions are associated with a reduced risk of death in critically ill adults with sepsis or septic shock compared with intermittent infusions. Data Sourc
Impaired rennet coagulation properties in milk could lead to prolonged processing times and production losses. Heritability for milk coagulation has previously been estimated to be 0.28 to 0.45, indicating that genetic selection can be used to manipulate this trait. The CN proteins are expressed by the genes CSN1S1, CSN2, CSN1S2, and CSN3 and are located on bovine chromosome 6. To better understan
Context. The light element (anti-)correlations shown by globular clusters (GCs) are the main spectroscopic signature of multiple stellar populations. These internal abundance variations provide us with fundamental constraints on the formation mechanism of stellar clusters. Aims. Using Gaia-ESO, the largest and most homogeneous survey of open clusters (OCs), we intend to check whether these stellar
BACKGROUND: Viral shedding and neutralizing antibody (NAb) dynamics among patients hospitalized with severe coronavirus disease 2019 (COVID-19) and immune correlates of protection have been key questions throughout the pandemic. We investigated the duration of reverse transcriptase-polymerase chain reaction (RT-PCR) positivity, infectious viral shedding and NAb titers as well as the association be
