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PURPOSE: The predictive value of excision repair cross-complementation group 1 (ERCC1) gene for survival and response to platinum-based chemotherapy in gastric cancer (GC) remains controversial. We performed a meta-analysis to clarify the precise estimation of the prognostic and predictive effect of ERCC1.METHODS: A systematic literature search was conducted using PubMed, ScienceDirect, Wiley and
Despite the increasing recognition of the critical role that nature-based solutions (NBS) play in urban resilience, decision-makers in many cities across the Global South continue to prioritize grey infrastructure and engineered solutions. This prevailing approach may offer short-term economic advantages but ultimately falls short in ensuring the long-term sustainability and resilience of communit
BACKGROUND: Little is known about whether the recommended, non-pharmacological treatments for chronic pain yield reductions in healthcare utilization, social costs and increased productivity in actual practice.METHODS: The primary aim of this study ( n = 232) was to conduct secondary analyses of health economic outcomes using data from national registries combined with clinical outcome data from
Knowledge of animal diets is fundamental in ecology as it can provide insight into the structure, function and resilience of entire ecosystems. In this study we investigate the diet composition of the harbour porpoise (Phocoena phocoena), a small marine top predator with great ecological importance, to provide updated dietary estimates for the species in Swedish waters. This is done by parallel us
The Japanese government's approval ratings are dropping fast ahead of elections in July
Background: Observational data on composite scores often comes with missing component information. When a complete-case (CC) analysis of composite scores is unbiased, preferable approaches of dealing with missing component information should also be unbiased and provide a more precise estimate. We assessed the performance of several methods compared to CC analysis in estimating the means of common
In recent years, the study of body image shifted from focusing on the negative aspects to a more extensive view of body image. The present study seeks to validate a measure of positive body image, the Body Appreciation Scale-2 (BAS-2; Tylka & Wood-Barcalow, 2015a) in Denmark, Portugal, and Sweden. Participants (N = 1012) were adolescents and young adults aged from 12 to 19. Confirmatory factor
BACKGROUND: This systematic review aims to determine the loads of anti-A and anti-B in plasma-containing blood products that can safely be transfused to adults.MATERIALS AND METHODS: A comprehensive literature search was performed in PubMed, including studies dating back to 1940 until January 1 st, 2023. In total 1,869 articles were screened, describing 86 cases of hemolytic transfusion reactions
Here we report on reactive Large Eddy Simulations (LES) of flow and combustion in the US Air Force Research Laboratory Research Cell 19 cavity-based scramjet combustor. This case involves combustion of ethylene (C2H4) injected into a cavity from its slanted trailing edge. It has previously been studied experimentally with multiple techniques including particle image velocimetry, shadowgrapy, OH pl
The driver of a conditionally automated vehicle equivalent to level 3 of the SAE is obligated to accept a takeover request (TOR) issued by the vehicle. Considerable research has been conducted on the TOR, especially in terms of the effectiveness of multimodal methods. Therefore, in this study, the effectiveness of various multimodalities was compared and analyzed. Thirty-six volunteers were recrui
Background: Fetal exposure to endocrine-disrupting chemicals (EDCs) has been associated with reduced male fecundity, but with few studies considering chemical mixtures. Objectives: We assessed the association between fetal exposure to a mixture of EDCs and biomarkers of male fecundity in young adulthood. Materials and methods: The study population comprised 841 young adult males enrolled in the Fe
To address the critical need for efficient biogas upgrading, this study systematically investigates the continuous absorption of CO2 and H2S from biogas using a choline chloride-monoethanolamine deep eutectic solvent (ChCl-MEA DES). Experiments were conducted in a continuous flow reactor under two scenarios: single-component absorption and simultaneous absorption of CO2 and H2S. The influence of k
This paper reviews the state of knowledge on past and present storms and marine coastal flooding (MCF) events of various origins within the Baltic Sea, which is an economically and environmentally important part of northwestern Europe. We show that the combination of sedimentary, historical and instrumental records provides the most comprehensive insight into the history of storms and MCF. The fre
Background World economies increasingly rely on non-standard employment arrangements, which has been linked to ill health. While work and employment conditions are recognized structural determinants of health and health equity, policies aiming to protect workers from negative implications predominantly focus on standard employment arrangements and the needs of workers in non-standard employment ma
The aim of this study is to analyse how a taxonomy-based course design can support students’ qualitative learning processes in online university courses. The paper presents a case study based on two online courses in comparative literature in Swedish and English. A document analysis has been applied to analyse the empirical material, which includes the syllabuses, study guides, and examination ass
Given incumbent-led autocratization in Tunisia, the article investigates support to democracy among youth in historically marginalized regions and the likelihood they will prefer the authoritarian alternative. Putting forth a framework for micro-level assessment of the cognitive and interpretive dynamics generating loss of popular support to democratic transition, the research problematizes the re
Background: Although up to 25% of proximal humeral fractures are isolated greater tuberosity fractures (IGTFs), comprehensive epidemiological data are lacking. Objectives: Describe the epidemiology and time trends of IGTF in Malmö, Sweden, 1944–2020. Methods: We identified IGTF in Malmö residents (≥18 years) by reviewing relevant radiology examinations during 17 sample years from 1944 to 2020. Fra
Introduction: Carbon monoxide (CO) is a leading cause of environmental poisoning in the United States with substantial mortality and morbidity. The mechanism of CO poisoning is complex and includes hypoxia, inflammation, and mitochondrial dysfunction. Currently both biomarkers and therapies for CO poisoning are limited and require new approaches. Methods: Rats (~ 300 g) were divided into four grou
BACKGROUND: Some per- and polyfluoroalkyl substances (PFAS) such as perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) are very long-lived in humans, with serum half-lives of several years. In PFAS hot spots, such as Ronneby, Sweden, high exposures over time have led to markedly elevated serum PFAS levels, which may result in health risks
