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Background: The ProtonCare Study Group (PCSG) was formed with the purpose to develop and implement a framework for evaluation of proton beam therapy (PBT) and the related care at a novel clinic (Skandionkliniken), based on patient reported data. Method: A logic model framework was used to describe the process of development and implementation of a structured plan for evaluation of PBT for all diag
Industry is increasingly committed to reduce its ecological footprint. One specific area of increased industrial interest is the use of plastic-free packaging. Plastic packaging is efficient from a supply chain perspective, but as waste risks causing disastrous environmental effects. This case study assesses the environmental impacts (from cradle to grave) of plastic cushioning inserts vs. corruga
Background: Vaccine development for Group B Streptococcus (GBS), a common cause of invasive disease in early-infancy and adverse pregnancy outcomes, include exploring widely-expressed GBS surface proteins as vaccine epitopes. We investigated the association between natural infant serum IgG against the RibN and Alp1N domains and risk of invasive GBS disease caused by isolates expressing these prote
BACKGROUND: Umbilical cord blood gases are routinely used by midwives and obstetricians for quality assurance of birth management and in clinical research. They can form the basis for solving medicolegal issues in the identification of severe intrapartum hypoxia at birth. However, the scientific value of veno-arterial differences in cord blood pH, also known as ΔpH, is largely unknown. By traditio
For older people mobility and participation in activities can be restricted both by individual factors and by the environment. The aim of this paper was to examine the longitudinal impact of measures taken in the outdoor environment on an ageing population. The following factors were examined on three occasions over a nine-year period: frequency of walking; differences in report on environmental b
The local synthesis and subsequent retrograde axonal transport of [35S]methionine‐labelled proteins was studied in the in vitro regenerating adult frog sciatic sensory axons. By the use of a three compartment culture system, proteins in the outgrowth region were selectively labelled. After 2 days in culture a rise in TCA‐insoluble radioactivity was detected in the dorsal root ganglia, which could
Objective: Men who have sex with men (MSM) in sub-Saharan Africa remain hidden and hard to reach for involvement in HIV and sexually transmitted infection (STI) services. The aim of the current study was to describe MSM social networks in a large and a small Tanzanian city in order to explore their utility for peer-based healthcare interventions. Methods: Data were collected through respondent-dri
Manual selection of finger trabecular bone texture regions on hand X-ray images is time-consuming, tedious, and observer-dependent. Therefore, we developed an automated method for the region selection. The method selects square trabecular bone regions of interest above and below the second to fifth distal and proximal interphalangeal joints. Two regions are selected per joint (16 regions per hand)
The purpose of the present research was to examine the effect of psychological distance and abstraction on judgment of ingroup moral transgressions. Based on Construal Level Theory (Trope & Liberman, 2010), we hypothesized that psychological distance and high level construal increases the degree to which moral value preference determines judgment (value-judgment correspondence) in response to
The effects of 1 min exposure to 80% CO2 inhalation was studied in rats under light general anaesthesia with N2O. It was found that 80% CO2 gave a rapid slowing of the EEG as well as a rapid decrease of the amplitude of cortical somatosensory evoked potentials. Only minor influences upon the blood pressure and heart rate were seen. The changes were found to be transient and most of the EEG effects
In Bernard-Soulier syndrome, a hereditary bleeding disorder, the platelets are deficient in the glycoprotein (GP) Ib-IX-V complex, a major receptor for the von Willebrand factor. The components of the complex are encoded by separate genes. Patients with this syndrome have a variable expression level of the receptor protein on platelets depending on the specific genetic abnormality. We describe a p
The kinetics for the reactions between the six complexes PtCln(H2O)4-n−2n, n = 0,1,2,3,4 (including cis- and trans-isomers for n=2) and the entering ligands Y = Cl−, Br−, I−, SCN−, and DMSO have been studied. The experiments with PtCl42− and trans- PtCl2(H2O)2 give the usual two-term rate constant kexp = k1 + k2[Y], when no extra chloride has been added to the solutions. The parameter k1 can be id
Context. Determining elemental abundances of bulge stars can, via chemical evolution modeling, help to understand the formation and evolution of the bulge. Recently there have been claims both for and against the bulge having a different [α/Fe] versus [Fe/H] trend as compared to the local thick disk. This could possibly indicate a faster, or at least different, formation timescale of the bulge as
The post-2015 developmental agenda and the SDGs have been formulated to advance holistic global progress and enable the adoption of quantitative targets for all countries by recognizing their respective national realities and capacities. This research examines how global ambitions can guide national policy formulation by selecting the Italian Republic and the People's Republic of Bangladesh as mod
Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommenda
The aim of this study was to illuminate spouses' perceptions of living with a partner who had been diagnosed with rectal cancer followed by surgery resulting in a stoma. The focus group interview was chosen as method of data collection. Two focus group interviews consisting of 2 meetings each were conducted. A qualitative content analysis was used. Five themes emerged: difficulties of being involv
The Middle Ordovician (Dapingian–middle Darriwilian) “orthoceratite limestone” is documented in its traditional type area at Kinnekulle in the province of Västergötland in southern Sweden. Detailed field studies combined with systematic qualitative and quantitative analyses of carbonate microfacies at high stratigraphic resolution show that this suite of cool-water carbonate rocks is more variable
OBJECTIVES AND METHODS: To ascertain the incidence/clinical implications of isolated autosomal trisomies in adult acute myeloid leukemia (AML), all such cases were retrieved from the Swedish AML Registry.RESULTS: Of the 3179 cytogenetically informative AMLs diagnosed January 1997-May 2015, 246 (7.7%) had isolated trisomies. The frequency increased by age (2.4% at age 18-60 years vs. 23% at >60 yea
