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In a population-based, matched case-control study from southern Sweden of 400 patients with a first diagnosis of malignant melanoma and 640 healthy control subjects aged 15-75 years, the association between commonly prescribed drugs, alcohol, smoking and malignant melanoma was evaluated. In addition, the relation between reproductive and hormonal factors and melanoma in women was studied. It was f
Aims and objectives: To explore the barriers for nutritional care as perceived by nursing staff at an acute orthopaedic ward, aiming to implement evidence-based nutritional care. Background: Previous studies indicate that nurses recognise nutritional care as important, but interventions are often lacking. These studies show that a range of barriers influence the attempt to optimise nutritional car
In this study we investigate different parameters used for mapping global flame structures and identify the most universal in terms of comparing flames emerging from different geometrical burner arrangements. Simultaneously the study was carried out to determine the discharge conditions yielding the blue flame of a high degree of partial premixing, and to examine the instantaneous local flame stru
CERN operates one of the most complex particle accelerator facilities in the world. Several different hazards, including fires, are present and need to be investigated and reduced to a tolerable level. Toward this goal, CERN aims at developing a catalog containing detailed fire dynamics descriptions of combustible items present in its facilities. This paper contributes to this catalog in two ways.
The interaction of oppositely charged lock- and key-colloids is investigated using computer simulations. We show that indented spheres, i.e., lock-particles, can be specifically assembled with spherical key-particles using solely electrostatic interactions in addition to a hard overlap potential. An analytic description of the entropic and energetic contributions is derived and supported by simula
Earth system models (ESMs) are key tools for providing climate projections under different scenarios of human-induced forcing. ESMs include a large number of additional processes and feedbacks such as biogeochemical cycles that traditional physical climate models do not consider. Yet, some processes such as cloud dynamics and ecosystem functional response still have fairly high uncertainties. In t
Evolution involves developmental change. Species comparisons play an important role in comparative cognition because they can uncover common patterns and shared principles in cognitive evolution. Developmental studies reveal foundational elements of cognitive abilities and how they are constructed and integrated. Sensorimotor cognition is such a key element that forms the foundation for later-deve
In computer simulations, long-range electrostatic interactions are surprisingly well approximated by truncated, short-ranged pair potentials. Examples are reaction field methods; the Wolf method; and a number of schemes based on cancellation of electric multipole moments inside a cut-off region. These methods are based on the assumption that the polarization of the neglected surroundings can be in
Importance: Although the most common recent approach in Alzheimer disease drug discovery is to directly target the β-amyloid (Aβ) pathway, the high prevalence of apolipoprotein E ϵ4 (APOE ϵ4) in Alzheimer disease and the ease of identifying ϵ4 carriers make the APOE genotype and its corresponding protein (apoE) an appealing therapeutic target to slow Aβ accumulation. Objective: To determine whethe
Antisocial personality disorder (ASPD) is one of the most common co-occurring disorders in substance abusers, characterized among other things by a high propensity for criminal actions. A cohort of 125 substance abusers were followed in a longitudinal design. Patients were diagnosed with ASPD at an index treatment episode, interviewed at five-year follow-up, and followed-up through the Swedish cri
Subarctic aerosol was sampled during July 2007 at the Abisko Research Station Stordalen field site operated by the Royal Swedish Academy of Sciences. Located in northern Sweden at 68 degrees latitude and 385 m above sea level (m asl), this site is classified as a semicontinuous permafrost mire. Number density, size distribution, cloud condensation nucleus properties, and chemical composition of th
This article presents an experimental investigation of cite heat transfer characteristics between the confined impinging slot jets and a fat surface. During the experiments, single slot, multiple slots with cross flow effects, and multiple slots with symmetrical exhaust ports between neighboring jets are tested The exhaust ports are manufactured to eliminate the cross-flow effects from the upstrea
Aims: (i) Determine whether between-observer reproducibility for Ki67 when assessed on whole sections according to a standardized scoring protocol is adequate for clinical application. (ii) Compare between-observer reproducibility of Ki67 scores assessed on hot-spots to scores using a global method that averages across a tissue section.Background: The nuclear proliferation biomarker Ki67 has multi
Turbulent flow and thermal field were predicted in a square-sectioned 180° bend at a Reynolds number of 56000. Suga's low-Re cubic k-ε model [5-6] and the RSM [7-8] were used. The results were compared to experimental data [1]. Identical inlet boundary conditions were used in both cases. The inlet length impact on the flow-heat transfer in the bend was investigated. The velocities are higher near
To achieve cleaner combustion and higher efficiency in compression ignition (CI) engines, many new combustion strategies have been developed. Among these new concepts, partially premixed combustion (PPC) attracts a lot of attention, because of its possibility to achieve simultaneously low soot and NOx. Compared to homogeneous charge compression ignition (HCCI) combustion, charge stratification in
Background: Current prostate cancer screening guidelines conflict with respect to the age at which to initiate screening. Objective: To evaluate the effect of prostate-specific antigen (PSA) screening versus zero screening, starting at age 50-54 yr, on prostate cancer mortality. Design, setting, and participants: This is a population-based cohort study comparing 3479 men aged 50 yr through 54 yr r
Accident prediction models are often used to predict the number of accidents on segments and at intersections in the road network. Most often the models are developed for a total number of crashes for the facility, or crashes by severity. However, the frequency and severity of crashes of different types can be expected to vary with regards to the underlying phenomena that cause them to occur. To b
