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Understanding the molecular determinants that underpin the clinical heterogeneity of non-muscle-invasive bladder cancer (NMIBC) is essential for prognostication and therapy development. Stage T1 disease in particular presents a high risk of progression and requires improved understanding. We present a detailed multi-omics study containing gene expression, copy number, and mutational profiles that
Introduction: Widening participation in education by including students from underrepresented groups has been recognized as important for the last decade. During the recent pandemic, the interest in how to make students from different backgrounds feel part of the university, and connected to their studies and peers, has become an even more widespread concern and therefore important to explore furt
BACKGROUND: Neutrophils and their inflammatory mediators are key pathogenic components in multiple autoimmune diseases, while their role in human type 1 diabetes (T1D), a disease that progresses sequentially through identifiable stages prior to the clinical onset, is not well understood. We previously reported that the number of circulating neutrophils is reduced in patients with T1D and in presym
The public health agency of Sweden has shown an increasing prevalence of mental illness among college students. At the same time studies show that students choose to not seek any help, and often don’t know where they would even find the help they might need. The aim of this study was therefore to map the prevalence of mental illness among students of Social Work at Campus Helsingborg, and examine
Ett patent är en immateriell rättighet som medför en ensamrätt för patenthavaren att dra affärsmässig nytta av en viss uppfinning under en begränsad tidsperiod. Den som kränker patenthavarens ensamrätt gör sig skyldig till patentintrång. Vid patentintrång tillhandahåller den svenska patentlagen (1967:837) ett antal olika sanktionsmöjligheter. De primära civilrättsliga sanktionsformerna utgörs av p
This research touches upon the influence of the museum as a media and the scepticist political framing of climate change in a U.S. context. By use of a two-step methodological approach, the thesis attempts to create a framework by which to understand the inner workings of the scepticist framing from a qualitative perspective. The thesis approaches the case from the onset that the case is the resul
Skatterättslig företrädaransvar innebär att en företrädare för ett bolag blir solidariskt betalningsansvarig med bolaget för dess obetalda skatter. När Skatteverket upptäcker obetalda skatter hos bolag och anser att företrädaren har agerat uppsåtligen eller grovt oaktsamt ansöker de om företrädaransvar hos förvaltningsrätten. Företrädaren kan sedan bli befriad från betalningsansvaret om särskilda Liability of a representative within the area of tax law means that a representative of a legal entity becomes jointly liable with the company for the company's unpaid taxes. When the Swedish Tax Agency discovers such an unpaid tax, they apply for liability of a representative at the administrative court if they consider that the representative has acted intentionally or grossly negligently. T
I ett försök att kunna straffa brott med rasistiska motiv hårdare infördes den s.k. straffskärpningsregeln, i 29 kap. 2 § 7 p. BrB under 1990-talet. Den ger domstolen möjligheten att skärpa straffet för ett brott, om motivet varit helt eller delvis hatiskt. Lagstiftaren har infört regeln för att skapa ett mer enhetligt och frekvent beaktande av hatmotiv, samtidigt som den ska fungera som ett förläIn an attempt to enable to punish crimes with racist motives the so called punishment harshening rule was added to the Penal Code during the 1990s. It gives the court the opportunity to harshen the punishment for a crime, if the perpetrator have had a hateful motive, competely or partially. The rule is legislated to create a more uniform and frequent consideration of hateful motives throughout the
The demand for space cooling is rising. The increase in cooling demand can put significant strain on the electric grid since approximately 99% of air-conditioning and refrigeration loads worldwide are met with electricity. Many hot weather cities could benefit from district cooling (DC) systems to meet their growing cooling demand in an effective sustainable manner. Since these systems require sig
In this project a model of oxygen, 16O, nuclei, where the nucleons are organised in α-clusters, was implemented in the Pythia Monte Carlo event generator. To study the effects of the new model, some observables, such as the distribution of the number of the wounded nucleons, charged particle multiplicity in the forward and central pseudorapidity region, and the pseudorapidity distribution for diff
The digital era has mercilessly affected the media landscape by changing the way information and news are disseminated and consumed. This has led to an increased need to move activities online and an outdated business model among newspapers. The Swedish newspaper industry has so far struggled to do business in the digital world. Hence, the need for business model innovation is greater than ever. I
This study parts from comparing two different kinds of readings of two short stories publicized under the literary gender fantastic feminism, and written by one of the most well-known authors in this genre, the Puerto-Rican Rosario Ferré. The stories analyzed are “El hombre dormido” (1976) (Man asleep, mi traducción) and “El sueño y su eco” (1976) (Sleep and its echo, mi traducción) given the simi
The purpose of this work is to investigate if Miljöbyggnad certification works well for a building company in different regions of Sweden, or if a new or revised working method needs to be developed. To achieve the purpose, the author bases the study from a couple of interviews. The conclusion of the study showed that the Miljöbyggnad certification is rarely required at the Swedish building comp
“Ripples in the water” is a qualitative research of eight family members´ experiences of the service they received from the psychiatric departments in the University Hospital in Iceland when one of the family became mentally ill. The eight participants in the research came from families, who had the total of six mentally ill patients. I conducted a total of six interviews with these participants,
Verification of the cleaning routines in a nut roastery The purpose of this report is to verify if the cleaning routines used in a specific nut roastery give an adequate cleaning and make the products microbiologically safe. Furthermore, controls of the products have been made with regard to allergens, personal hygiene, cooling, water content, water activity and the level of oxygen left in the pac
The purpose of this study was to examine the views on collaboration between the municipality (social services) and the psychiatric health care sector. More specifically its aim was to find out how collaboration currently is described by different representatives within the two organizations and to analyze these findings. The goal of the study was to reach a better understanding of the priorities m
The purpose of this master thesis in practical theology is to investigate the reasons for choices of hymns made by parents baptising their children in the Church of Sweden. From earlier data on baptisms and hymns we do know which hymns are most commonly chosen, but no one to date has interviewed parents on their choices. The method used is semi structured interviews of eleven parents whose childre
When being in a noisy environment, a normal hearing person can manage to sort out background noise and focus on the attended source. This is something that a person with impaired hearing will struggle with, even when wearing a hearing aid. Research for developing intelligent hearing aids has not yet come up with a solution for solving this problem and more research is needed. This thesis uses data
Infectious diseases are one of the leading causes of mortality in the world. Severe infections can manifest in many ways, creating a heterogeneous clinical and molecular disease landscape that renders these diseases difficult to research, diagnose, and treat. To investigate the molecular mechanisms of infectious disease, we apply mass spectrometry-based proteomics to analyze blood plasma samples f
