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Colorectal cancer (CRC) is one of the most common cancer worldwide. However, a large number of genetic risk factors involved in CRC have not been understood. Copy number variations (CNVs) might partly contribute to the missing heritability of CRC. An increased overall burden of CNV has been identified in several complex diseases, whereas the association between the overall CNV burden and CRC risk
Background: In obese patients, jejunoileal bypass (JIB) has been used to induce weight reduction. Changes in the neuroendocrine system may be affected by the JIB-operation, because the proximal small intestinal mucosa has a rich supply of endocrine cells and peptidergic nerves. Materials and Methods: In 37 obese patients operated with JIB 1-30 years ago, small intestinal biopsies were taken at the
Background: There is increasing appreciation of gender differences in COPD but scant data whether risk factors for tow lung function differ in men and women. We analysed data from 3 years follow-up in 178 women and 464 men with COPD, participants in the Euroscop Study who were smokers unexposed to inhaled corticosteroids. Methods: Explanatory variables of gender, age, starting age and pack-years s
The importance of the home environment increases with age. Perceived aspects of home influence life satisfaction, perceived health, independence in daily activities and well-being among very old people. However, research on health and perceived aspects of home among senior citizens in earlier phases of the aging process is lacking. Therefore, the main aim was to explore whether perceived aspects o
Recent advances in experimental plant biology have led to an increased potential to investigate plant development at a systems level. The emerging research field of Computational Morphodynamics has the aim to lead this development by combining dynamic spatial experimental data with computational models of molecular networks, growth, and mechanics in a multicellular context. The increased number of
This paper studies contextual effects on fertility at the onset of fertility decline in Sweden. We argue that the community exerts an influence on fertility when individuals belonging to a certain community are more similar to one another (within-area) in their reproductive behaviour than individuals living in another community (between-area). Our hypotheses are that community had a strong influen
New technology requirements derived from the exploitation of novel energy resources, and the needs for improvement of the energy efficiency of current power generation systems are pushing the industry towards the search of alternative working fluids. The great challenge for these non-conventional fluids is to provide satisfactory performances and fill the existing lack of media for some innovative
Popular Abstract in Swedish Lera-vatten-systemet finns i stort sett överallt i vår omgivning. Syftet med denna avhandling är att identifiera och undersöka egenskaper hos leror som är av betydelse för deras inbördes växelverkan. Leror är sammansatta av två eller tre molekylära lager och får därför en relativt komplex fördelning av elektrostatiska laddningar. Denna fördelning förändras med olika bet
This paper focuses on the complicated matter of interpreting the use of Roman drinking vessels found in Roman Iron Age graves in Scandinavia. It will primarily build on a number of theoretical standpoints, which are believed to broaden our understanding of the presence of these vessels in the Scandinavian mortuary context, and give us alternatives to the conventional interpretations within Roman I
The binding between colipase and two triacylglycerol substrates, tributyrin and Intralipid, in the presence of bile salts have been determined quantitatively by a method based on equilibrium partition in an aqueous two-phase system. In the model proposed the triacylglycerol, in the form of spherical droplets covered with bile salt, is assumed to have a certain number of independent binding sites a
This paper presents theory and algorithms for validation in system identification of state-space models from finite input-output sequences in a subspace model identification framework. Similar to the case of prediction-error identification, it is shown that the resulting model can be decomposed into an input-output model and a stochastic innovations model. Using the Riccati equation, we have desig
Background: Being foreign born, i.e. not born in the reception country or belonging to an ethnic minority, has been described as a risk factor of problem gambling, although research so far has been inconclusive. Also, there is limited knowledge about whether this association is caused by differing gambling norms. The present study aimed to study whether foreign origin is associated with problem ga
A feed-forward neural network method is developed for reconstructing the invariant mass of hadronic jets appearing in a calorimeter. The approach is illustrated in W→qq, where W-bosons are produced in pp reactions at SPS collider energies. The neural network method yields results that are superior to conventional methods. This neural network application differs from the classification ones in the
The analytical technique of ion beam thermography (IBT) is reported for the first time. IBT is a technique for the determination of chemical compounds. This IBT setup combines the multielemental ion beam technique's particle-induced X-ray emission (PIXE) and particle elastic scattering analysis (PESA) with thermography. A large number of elements are monitored with PIXE (Z > 14) and PESA (hydrogen
Autoignition in SI engines is an abnormal combustion mode and may lead to engine knock in SI engines. Knock may cause damage and it is a source of noise in engines. It limits the compression ratio of the engine and a low compression ratio means low fuel conversion efficiency of the engine. In this paper a multi zone model based on an existing two zone model Hajireza et al., [1 and 12] and Stenlaas
