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Introduction: Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel progn
This masters thesis deals with mathematical signal detection in the field of NQR,Nuclear Quadrapole Resonance, which is a non-invasive spectroscopic technique usedto identify specific substances. The thesis has two main focuses, where the first isto propose novel methods for parameter estimation, especially for identification ofunknown signals. These extend the existing Capon and APES methods for
Early life air pollution exposure may play a role in development of respiratory infections, but underlying mechanisms are still not understood. We utilized data from two independent prospective birth cohorts to investigate the influence of prenatal and postnatal ambient air pollution exposure of PM2.5, PM10 and NO2 on maternal and child proteomic profiles and the risk of daily diary-registered com
(Formula presented) boson events at the Large Hadron Collider can be selected with high purity and are sensitive to a diverse range of QCD phenomena. As a result, these events are often used to probe the nature of the strong force, improve Monte Carlo event generators, and search for deviations from standard model predictions. All previous measurements of (Formula presented) boson production chara
Given the increasing number of heterogeneous data stored in relational databases, file systems or cloud environment, it needs to be easily accessed and semantically connected for further data analytic. The potential of data federation is largely untapped, this paper presents an interactive data federation system (https://vimeo.com/319473546) by applying large-scale techniques including heterogeneo
Despite a wealth of sophisticated CFD-methods, most designs are still based on one-dimensional and two-dimensional inviscid analytical tools. In such methods, realistic loss and angle assessment are indeed critical in order to arrive at correct loading, flow coefficient and reaction. The selected values are normally retained through the detailed design sequence for each iteration. This means that
Popular Abstract in Swedish Framgångsrik strålbehandling av cancerpatienter kräver att man kan bestämma den absorberade dosen i patienten med stor noggrannhet. Bara några enstaka procents avvikelse i absorberad dos kan ha betydelse för det kliniska resultatet avseende både tumörutläkning och normalvävnadsreaktioner. För att beräkna den absorberade dosen i patienten används sofistikerade datorprogThe accuracy of dose calculations for various aspects of a treatment planning system (TPS) using an energy fluence beam modelling has been evaluated. The investigated TPS uses a beam model, which separates the energy fluence into a number of sources in the treatment head. The energy fluence components are transported towards the patient and, together with the scatter generated in the patient, yiel
Popular Abstract in Swedish Vi använder allt mer energi och efterfrågan kommer bara öka, fram till 2050 spås en fördubbling av världens efterfrågan av energi. Drygt 85 procent av den energi som produceras i dag kommer från fossila bränslen som bidrar till växthuseffekten. En ny rapport från FN:s klimatpanel, IPCC, visar att koldioxid står för runt 76 procent av det totala utsläppet av växthusgasAccelerating actions to mitigate CO2 emissions was one of the important messages at the UN Climate Summit 2014. About 85 % of the world’s energy is provided through the burning of fossil fuels, which is the main source of CO2 emissions. Increasing the share of renewable energy, and making energy efficiency improvements and savings were actions that were agreed upon to meet CO2 emission reductions.
Context. Globular clusters (GCs) carry information about the formation histories and gravitational fields of their host galaxies. It was found before that the radial profiles of the volume number density of GCs in GC systems (GCSs) follow broken power laws, while the breaks occur approximately at the a0 radii. These are the radii at which the gravitational fields of the galaxies equal the galactic
BACKGROUND: The wasabi receptor, also known as the Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel, is a potential target for development of repellents for insects, like the pine weevil (Hylobius abietis) feeding on conifer seedlings and causing damage in forestry. Heterologous expression of TRPA1 from pine weevil in the yeast Pichia pastoris can potentially provide protein for structur
BackgroundIn mid-March 2020, a range of public health and social measures (PHSM) against the then new coronavirus disease (COVID-19) were implemented in Denmark, Norway and Sweden.AimWe analysed the development of influenza cases during the implementation of PHSM against SARS-CoV-2 in the Scandinavian countries.MethodBased on the established national laboratory surveillance of influenza, we compar
We live in an era that suffers from climate change issues, not least disaster risks induced by climate change. While measures, such as proper evacuation plans, are required to reduce the negative impacts of disasters when they hit, actions should also be taken to reduce climate change effects by e.g. increasing the use of renewable energies or proper urban land-use allocation, where climate change
Human activities in coastal areas have accelerated during the last 200 years. Environmental changes resulting in a combination of three threats, i.e., deoxygenation, warming, and ocean acidification, impact particularly sub-polar regions. To better understand these environmental challenges, we need to develop tools to compare our present situation with previous periods less impacted by anthropogen
Background: The incorporation of artificial intelligence (AI) into point-of-care ultrasound (POCUS) platforms has rapidly increased. The number of B-lines present on lung ultrasound (LUS) serve as a useful tool for the assessment of pulmonary congestion. Interpretation, however, requires experience and therefore AI automation has been pursued. This study aimed to test the agreement between the AI
