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It is argued that we live in a post-industrial society with a transition from the production of goods to services. It is also said we live in a knowledge economy where creation, distribution, use and manipulation of information are significant activities (Dahlbom, 2003). The word industrial has a connotation of mass-production of products and, logically also industrial design has this connotation.
This thesis concerns the experimental study of mixing and flow characteristic in turbulent circular impinging jets without and with jet orifice manipulators (i.e. passive-fixed perturbations atthe nozzle exit), without and with swirl. The goal of the studies is to understand the basic mechanisms that control the mixing processes in turbulent impinging jets. The applications of such mixing processe
Teaching history in multicultural societies – Case study Malmo (Sweden) German Minister of Education and Research, Annette Schavan recently presented a proposal concerning a common European History Book. According to Deutsche Welle she underlined that “education is essential for shaping identity and for social cohesion in Europe”. Therefore it is possible to conclude that the content of history a
The present study was aimed at identifying genetic variants in susceptibility to childhood acute lymphoblastic leukemia (ALL) through replication and validation of polymorphisms selected from two genome wide association studies. The first part of the study was based on the replication of polymorphisms selected from a previously conducted genome wide scan using 50K DNA-SNP microarrays. 47 selected
Faryngotonsillit, eller halsfluss, är en vanlig orsak till att patienter söker primär-vård och är även en vanlig orsak till antibiotikaförskrivning. Bakterien Grupp A-streptokocker (GAS) har sedan länge varit den viktigaste mikroorganismen vid halsfluss, inte minst på grund av dess koppling till följdsjukdomar som exempelvis reumatisk hjärtsjukdom, men det finns många andra bakterier och virus somPharyngotonsillitis, or acute sore throat, is a common reason for attending primary health care and a common reason for antibiotic prescription. Group A Streptococcus (GAS) has long been considered the most important pathogen in pharyngotonsillitis, but a wide array of other bacteria and viruses have also been associated with this condition. However, few studies have used modern approaches for aet
BACKGROUND One of the most challenging tasks of modern biology concerns the real-time tracking and quantification of mRNA expression in living cells. On this matter, a novel platform called SmartFlareTM has taken advantage of fluorophore-linked nanoconstructs for targeting RNA transcripts. Although fluorescence emission does not account for the spatial mRNA distribution, NanoFlare technology has g
Doxorubicin (DOX) is a cornerstone drug in the treatment of osteosarcoma. However, achieving sufficient concentration in the tumor tissue after systemic administration with few side effects has been a challenge. Even with the most advanced nanotechnology approaches, less than 5% of the total administered drug gets delivered to the target site. Alternatives to increase the local concentration of DO
Among nanoscale structures of different shapes and dimensions nanowires are one of the most promising because of its truly unique properties different from their bulk counterparts. The energy quantization, perfect defect-free structure, and the possibility to grow them within the miscibility gap in combination with the benefits of bottom-up design and the possibility of integration on silicon subs
Background: Elderly persons with a dementia diagnosis often suffer from different neuropsychiatric symptoms (NPS) such as delusions, hallucinations, depression, anxiety, irritability and agitation. Currently, the medical treatment for NPS consists mostly of psychotropic medication such as hypnotics/sedatives, anxiolytics and antipsychotics. In elderly persons with dementia, usage of antipsychotics
Access to compatible blood for transfusion is a prerequisite for modern health care. The compatibility is limited by the presence of antibodies to blood group antigens, polymorphic protein and carbohydrate structures, on the surface of the red blood cell. Blood group antigens arise from genetic variation in the genes underlying their expression. Knowledge of these genes and their variation can fac
BACKGROUND: There is a gap in knowledge on long term pace of population aging acceleration and related net-migration rate changes in WHO European Region and its adjacent MENA countries. We decided to compare European Union (EU-28) region with the EU Near Neighborhood Policy Region East and EU Near Neighborhood Policy Region South in terms of these two essential features of third demographic transi
Objectives To study fully automated digital joint space width (JSW) and bone mineral density (BMD) in relation to a conventional radiographic scoring method in early rheumatoid arthritis (eRA). Methods Radiographs scored by the modified Sharp van der Heijde score (SHS) in patients with eRA were acquired from the SWEdish FarmacOTherapy study. Fully automated JSW measurements of bilateral metacarpal
Context. Recent spectroscopic surveys have begun to explore the Galactic disk system on the basis of large data samples, with spatial distributions sampling regions well outside the solar neighborhood. In this way, they provide valuable information for testing spatial and temporal variations of disk structure kinematics and chemical evolution. Aims. The main purposes of this study are to demonstra
Background: Migration from Thailand to Sweden has increased threefold over the last 10 years. Today Thailand is one of the most common countries of origin among immigrants in Sweden. Since the year 2000, new HIV cases are also more prevalent among Thai immigrants compared to other immigrant nationalities in Sweden. The purpose of this study was to investigate the association between knowledge and
Background: There is an urgent need to improve patient safety in the area of medication treatment among the elderly. The aim of this study was to explore which improvement needs and strengths, relating to medication safety, arise from a multi-professional intervention in primary care and further to describe and follow up on the agreements for change that were established within the intervention. M
Introduction: Detection of circulating tumour cells (CTCs) in peripheral blood has an established prognostic significance in patients with metastatic breast cancer. Change in the number of detected CTCs is also an indication of response to therapy. Characterisation of CTCs could provide easily accessible treatment predictive information of present cancer cells within the patient and could reveal i
Höftprotesoperationer har blivit ett säkert och mycket framgångsrikt kirurgiskt ingrepp och lever upp till mycket av de förväntningar som patienterna har. Förbättring av material, protesdesign och kirurgiska tekniker har förlängt protesöverlevnaden påtagligt. Emellertid är icke optimal protesplacering och felaktigt val av komponentstorlekar känt för att öka risken för biomekaniska problem och ökatTotal hip arthroplasty (THA) has become a safe and very successful surgical intervention. A vast majority of patients get their expectations met. Improvement of materials, implant designs, and surgical techniques, have extended prosthetic survival. However, inferior placement and sizing of a hip prosthesis are known to increase the risk of mechanical failure, wear, and early loosening as well as p
The central challenge tackled in this thesis is the development of an optical imaging approach capable of multidimensional image capture of dynamic samples. Many conventional optical imaging approaches, which can obtain dimensional information such as spectral, polarisation, or volumetric, to name a few, about samples either employ sequential image capture or parallelised detector arrangements. Du
BACKGROUND: Most trials that have shown a benefit of beta-blocker treatment after myocardial infarction included patients with large myocardial infarctions and were conducted in an era before modern biomarker-based diagnosis of myocardial infarction and treatment with percutaneous coronary intervention, antithrombotic agents, high-intensity statins, and renin-angiotensin-aldosterone system antagon
