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Background: The introduction of highly active antiretroviral therapy has significantly improved the life expectancies of children and adolescents living with HIV, leading to an increased number transitioning to adult care. However, there has been a lack of studies in Ethiopia focusing on factors influencing the success of this transition. Therefore, this study aimed to determine predictors of a su

Background: Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and efficacious in reducing OFF-time in two pivotal trials in patients with PD and end-of-dose motor fluctuations. The OpiCapone Effect on motor fluctuations

BACKGROUND: The risk of death from prostate cancer (PC) depends on age, but the age at which to start prostate-specific antigen (PSA) screening remains uncertain.OBJECTIVE: To study the relationship between risk reduction for PC mortality and age at first PSA screening.DESIGN, SETTING, AND PARTICIPANTS: The randomized Göteborg-1 trial invited men for biennial PSA screening between the ages of 50 a

Background: Children in families who are refugees might experience more adversities than their peers. Adverse childhood experiences (ACEs) are well known risk factors for poorer adulthood health and adjustment. The risk of ACEs for children with a parent who is a refugee affected by trauma is unknown. We aimed to estimate the hazard of individual and cumulative ACEs using a unique sample of childr

The radiative properties of clouds depend partially on the cloud droplet number concentration, which is determined by the concentration of cloud condensation nuclei (CCN) when the clouds are formed. In turn, CCN concentrations are determined by the atmospheric particle size distribution and their chemical composition. We use a novel Lagrangian modelling framework to examine the origins and history

This paper summarized the efforts performed to understand decay heat estimation from existing spent nuclear fuel (SNF), under the auspices of the Working Party on Nuclear Criticality Safety (WPNCS) of the OECD Nuclear Energy Agency. Needs for precise estimations are related to safety, cost, and optimization of SNF handling, storage, and repository. The physical origins of decay heat (a more correc

IMPORTANCE: The introduction of solid or semisolid foods alongside breast milk plays a vital role in meeting nutritional requirements during early childhood, which is crucial for child growth and development. Understanding the prevalence of zero-food children (defined for research purposes as children aged 6 to 23 months who did not consume animal milk, formula, or solid or semisolid food during t

Semiconductor materials (e.g., conjugated polymers, metal halide perovskites) have been widely used in solar cells, light-emitting diodes, and photodetectors. Organic conjugated systems have high mechanical flexibility and low costs for production. Metal halide perovskites have the advantage of strong light absorption, long charge-carrier diffusion lengths, and low intrinsic surface recombination.

Background: Prognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of intensive care could produce a reliable model for

Purpose: This investigation was designed to examine the effects of self-monitored training combined with the use of delayed auditory feedback (DAF), on the accuracy of articulation in acquired apraxia of speech (AOS). Background: The increased number of stroke survivors leads to higher societal costs when it comes to e.g., rehabilitation. Speech and language deficits post stroke can be diminished

Background: Optimal long-term follow-up (LTFU) care for survivors of childhood, adolescent and young adult (CAYA) cancer can improve or maintain their quality of life by prevention and early treatment of late effects. However, optimal LTFU care is not provided to all CAYA cancer survivors. This systematic review sought to identify associated barriers, facilitators and other factors of LTFU care fo

Lean premixed dry low emission (DLE) combustion system in a gas turbine engine is a globally accepted concept to reduce pollutant emissions and to improve combustion efficiency. This study is focused on an industrial downscaled prototype burner (4th Generation Dry Low Emission Burner for SGT-750 designed and manufactured by Siemens Industrial Turbo machinery AB), which has been tested extensively

Mineralogical and geochemical studies of the non-marine Permian–Triassic (P–Tr) boundary across two stratigraphically wellconstrained sections (Commando Drift Dam and Wapadsberg, Eastern Cape Province) in the southern Karoo Basin, South Africa, have been undertaken to provide further input on the cause of this mass extinction event, and so has a sedimentological and geochemical evaluation of a thi

Among Swedish Hieracium sect. Oreadea (Fr.) Arv.-Touv., more than 100 taxa have been recognized by various experts but, except for a regional monograph from 1894 there are no thorough published revisions of the group and many of the names have never been validly published. At the same time, some of the oldest names have been variously applied to morphologically clearly different species. In the pr

Reprogramming of somatic cells into pluripotency stem cell state have opened new opportunities in cell replacement therapy and disease modeling in a number of neurological disorders. It still remains unknown, however, to what degree the grafted human induced pluripotent stem cells (hiPSCs) differentiate into a functional neuronal phenotype and if they integrate into the host circuitry. Here we pre

The currently used 8% fragrance mix (FM I) does not identify all patients with a positive history of adverse reactions to fragrances. A new FM II with 6 frequently used chemicals was evaluated in 1701 consecutive patients patch tested in 6 dermatological centres in Europe. FM II was tested in 3 concentrations - 28% FM II contained 5% hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral((R))), 2% ci

During the last two decades, the synthesis of silica with an ordered mesoporous structure has been thoroughly explored. The basis of the synthesis is to let silica monomers polymerize in the presence of an amphiphilic template component. In the first studies, cationic surfactants were used as structure inducer. Later it was shown that pluronic copolymers also could have the role. One advantage wit

Popular Abstract in Swedish Avregleringen av elmarknaden uppmuntrar kraftbolag och oberoende kraftproducenter till att driva sina kraftverksanläggningar på ett marknadsorienterat sätt. För att behålla de ekonomiska marginalerna på plussidan så har de mest populära åtgärderna varit att förbättra elverkningsgraden genom ändringar i hårdvaran samt höja totalverkningsgraden genom till exempel samproduThe deregulation of the electricity market drives utilities and independent power producers to operate heat and power plants as profit centers. In order to keep the economic margins on the credit side, the preferred measures have been to improve the electrical efficiency through changes in the hardware and boost the overall efficiency through e.g. combined heat and power (CHP) generation. The bett

The East Asian monsoon has a strong seasonal effect on the rainfall regime of Eastern China. In order to mitigate floods and conserve the water for use throughout the year, dams and other hydro-structures are built. The design of the structures requires knowledge of the rainfall characteristics that influence the inflow to them. In this thesis, the properties of heavy rainfall in a 73 000 km2 area

Aims. Observational studies of the Milky Way bulge are providing increasing evidence of its complex chemo-dynamical patterns and morphology. Our intent is to use the iDR1 Gaia-ESO Survey (GES) data set to provide new constraints on the metallicity and kinematic trends of the Galactic bulge, exploring the viability of the currently proposed formation scenarios. Methods. We analyzed the stellar para