Filetype
Background: Survivors of childhood acute lymphoblastic leukemia (ALL) may be at increased long-term risk of hospitalization for somatic diseases. However, large population-based cohort studies with risk estimates for survivors successfully cured without experiencing a relapse or requiring hematopoietic stem cell transplantation (HSCT) are lacking. Methods: Danish and Swedish patients diagnosed wit
Background: Childhood (< 20 years) nervous system tumors manifest in some rare cancer syndromes but how commonly they present with familial clustering between various histological types is not well known at a nation-wide level. Our aim is to enhance understanding of familial risks in childhood nervous system cancers. Methods: We used the Swedish population and cancer data from years 1958–2021 to a
Background: Because breast cancer (BC) is molecularly heterogeneous, diagnosis and treatment will likely benefit from comprehensive genetic profiling. However, routine, high-resolution sequencing is not feasible yet, due to implementation challenges associated with whole-genome sequencing of formalin-fixed paraffin embedded (FFPE) BC samples. Therefore, we explored the potential of an alternative
Background: Standardized care pathway (SCP) for macrohematuria (patients aged ≥50 years) in Sweden includes four-phase computed tomography urography (CTU) before cystoscopy, but targeted SCP lead time for CTU (6 days)/treatment is fulfilled in <25% of patients. Purpose: To retrospectively analyze the incidence of CTU-diagnosed upper urinary tract (UUT), kidney and bladder tumors, calculi, radiatio
In this paper, we investigate a Multi-layer Aerial system for GenAI inference at the Edge (MAGE). Therein, ground user equipments (UEs) request image synthesis services from a remote base station (BS) that leverages the Latent Diffusion Model (LDM) for image generation. Multiple Unmanned Aerial Vehicles (UAVs) are deployed to serve the UEs for relaying their images and prompts to the BS. To reduce
The evacuation of hospitals in the event of fires and similar emergencies can be a difficult endeavor. Patients usually require assistance, with a considerable number of them being unable to evacuate by themselves due to medical conditions or due to the treatment they are receiving. Assistance is to be provided by the healthcare staff in the affected ward, which means that their level of preparedn
I entreprenadformen totalentreprenad upphandlar entreprenören konsulten och har därmed ansvar för både projektering och utförande. För att öka produktiviteten och innovationsgraden i järnvägsprojekt ökade Trafikverket antal projekt upphandlade som totalentreprenader mellan år 2012 och 2018. Det skapade en stor ovana för aktörerna i sättet att arbeta. Idag har företagen i järnvägsbranschen vant sigIn design-build contracts the contractor purchase the consultant and is therefore responsible for both design and execution. To increase productivity and innovation in railway projects Trafikverket, Swedish Transport Administration, increased the number of design-build contracts between 2012 to 2018. This created large unfamiliarity in the way of working for the actors. Today the companies in the
Background: Glioblastoma is the most common primary malignant brain tumor in adults. Elevated interstitial fluid pressure (IFP) within the tumor restricts drug uptake and contributes to the dismal prognosis. Antisecretory factor (AF) is an endogenous protein that possesses antisecretory and immunomodulating properties. In vivo, AF can reduce elevated IFP. There are two AF-enhancing products; Salov
Physical phenomena that are unexplained by the Standard Model (SM) of particle physics, are the subject of the area of research known as physics Beyond the Standard Model (BSM). BSM physics contains many Dark Matter (DM) theories which have emerged; from particles such as axions, neutrinos, and Weakly Interacting Massive Particles (WIMPs), to primordial black holes and others. The range of exper
Abstract Title: Project managers – The invisible leaders Authors: Stefan Karlsson and Christoffer Karlsson Supervisor: Radhlinah Aulin, Division of Construction Management, Lund Faculty of Engineering Problem: * What are the most important work tasks for a project manager * What are the most important skills in the role as a project manager * What kind of common problems and difficulties are a pro
The aim of this master thesis is to provide an indication of the suitability, or otherwise usage, of spray-drying for production of powder aimed for inhalation formulation and comparing the characteristics of the product, with and without lipids. Lipids have a proven effect of delaying release of active drug substances in the cardiovascular system and pulmonary systemic delivery has a number of ad
Attitudes towards littering A study of residents’ attitudes towards littering in public spaces in Malmö city All forms of littering are considered a crime according to the chapter 15 § 30 of the Swedish Environmental Code. Still, littering is considered an increasing rather than a decreasing phenomenon. The results of littering are not just esthetical nuisance and increased street cleaning costs b
The present thesis, adopting the ecology of language as its conceptual orientation as well as employing linguistic landscape as its methodological tool to collect and analyze data, firstly aims at investigating (1) how the four official languages of Singapore namely Malay, (Mandarin) Chinese, Tamil, and English have been deployed on signs by three different social actors, i.e., the Singaporean gov
Even though protonemal development of bryophytes has been well studied, it remains unknown whether interspecific competition among mosses species affects their early growth and development. This study evaluated the effects of interspecific competition on in vitro germination and gametophyte development between each pair-wise combination from six common moss species: Atrichum undulatum, Bryum argen
Hållbar utveckling är ledordet inom såväl miljöpolitiken som miljörätten, däri inbegrips bland annat bevarandet av biologisk mångfald. Trots det bedöms Sverige bara nå två av 16 miljökvalitetsmål inom utsatt tid. Inom flera av områdena som rör bevarandet av biologisk mångfald och värdefulla naturmiljöer går utvecklingen dessutom åt fel håll. Uppsatsen syftar till att utreda hur rätten kan förändrIn environmental policy, as well as in environmental law, sustainable development is the keyword. To achieve this, preservation of biodiversity is central. Despite this, Sweden is expected to reach only two out of 16 environ-mental quality goals in time. Furthermore, in a number of areas relating to the preservation of biological diversity and valuable natural environments, development is made in
Examensarbetet syftar till att jämföra olika insamlingssystem för matavfall från flerfamiljshus. För att uppnå Sveriges miljömål finns etappmål som anger att minst 50 % av matavfallet ska källsorteras och behandlas biologiskt för att ta tillvara på energi och/eller näring till senast år 2018. Detta innebär att antalet hushåll med tillgång till separat sortering av matavfall måste öka. Det vanligaTo facilitate the fulfilment of Sweden’s environmental objectives, there are interim targets regarding e.g. food waste. For instance: at least 50 % of food waste should be source separated and biologically treated to make use of energy and/or nutrients, by 2018 the latest. To achieve this, the number of households with access to separate collection of food waste must increase. The aim of this mas
The main goal of this thesis was the development and application of a method to construct reactor networks based on pre-calculated flow fields for combustion systems. Computational fluid dynamics (CFD) was used to calculate flow fields for the Sandia piloted jet flame D and a Siemens SGT-800 gas turbine burner rig. Two different combustion models were tested in the computational fluid dynamics cal
The core business of Sandvik SRP AB are rock crushers. Today Sandvik evaluates the welded joints by simplified and somewhat conservative methods. The task is to investigate alternative weld evaluation methods. This have been done by creating different submodels of the area of interest, where the welds is represented in different ways. Different element types have been used, by following recommen
Two methods of computational analysis of DNA barcodes are presented. A DNA barcode is formed by making GC-rich regions of a DNA molecule fluoresce while AT-rich regions remain dark, thus when stretched using nano-channels and viewed in a microscope, the DNA molecule will resemble a barcode with black and white stripes. Because of point-spread functions and pixellation the resolution will be roughl
