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Background: We hypothesised that observed annual incidence rates of ANCA-associated vasculitis (AAV) are driven bysporadic short-term, high-intensity rates characterised as clusters of diagnosis events in time. Using data from Ireland, Swedenand Spain, we performed a changepoint analysis to discover time intervals with high and low rates of vasculitis diagnosis.Methods: We recruited 417 patients f
Today’s digitalized society relies on the advancement of silicon (Si) Complementary Metal Oxide Semiconductor (CMOS) technology, but the limitations of down-scaling and the rapidly increasing demand for added functionality that is not easily achieved in Si, have pushed efforts to monolithically 3D-integrate III-V devices above the Si-CMOS technology. In addition, the demand for increased computati
Background: Quantitative cardiovascular magnetic resonance (CMR) first pass perfusion maps are conventionally acquired with 3 short-axis (SAX) views (basal, mid, and apical) in every heartbeat (3SAX/1RR). Thus, a significant part of the left ventricle (LV) myocardium, including the apex, is not covered. The aims of this study were 1) to investigate if perfusion maps acquired with 3 short-axis view
Background: Somatostatin receptor 68Ga PET imaging is standard for evaluation of a patient’s suitability for 177Lu peptide receptor radionuclide therapy of neuroendocrine tumours (NETs). The 68Ga PET serves to ensure sufficient somatostatin receptor expression, commonly evaluated qualitatively. The aim of this study is to investigate the quantitative relationships between uptake in 68Ga PET and ab
Biomass is an environmentally friendly renewable energy source and carbon-neutral fuel alternative. Direct combustion/gasification of biomass in the dense particle-fluid system is an important pathway to biomass energy utilization. To efficiently utilize biomass for energy conversion, a full understanding of biomass thermal conversion in lab/industrial-scale equipment is essential. This thesis aim
Popular Abstract in English Freezing is a commonly used method of preserving food products including fruits and vegetables. A fresh-like texture and appealing visual appearance of frozen and thawed plant food products are of key importance for customer acceptance. Therefore, the food industry is constantly looking for ways to improve freezing techniques, especially for sensitive plant tissues suchFreezing is a widely used method of preserving food products. Efforts are currently being directed towards improving the quality of the sensitive tissues of plant foods such as leaves, after freezing and thawing. One of the methods under investigation is the combination of vacuum impregnation (VI) with cryoprotectants and the application of a pulsed electric field (PEF) to the plant tissue prior t
Bladder cancer is the ninth most common type of cancer globally, and the projected number of deaths is estimated to almost double by the year 2040. Immunotherapy with checkpoint inhibitors has revolutionized treatment of bladder cancer and can achieve durable responses; however, only a minority of patients respond. By identifying additional targets and treatment combinations, more patients could b
INTRODUCTION: Survival and healthcare for patients with congenital heart disease have improved, and the number of pregnancies among women of childbearing age with congenital heart disease has increased. Our aim was to investigate obstetric outcomes in a large retrospective, national registry study of women with congenital heart disease compared to controls.MATERIAL AND METHODS: The study included
Companies share their intellectual property with potential competitors in many different ways, including patent pooling. A patent pool is an agreement between two or more patent owners to license one or more of their patents to one another or to third parties. In Europe the Commission used the term patent pool as the bringing together of the patents of two companies, which makes it available for u
Var femte fall av dödligt våld i Sverige år 2018 bestod av dödligt våld mot kvinnor där offret och förövaren var eller hade varit i en parrelation. Mäns dödliga våld mot kvinnor i nära relationer är ett omfattande samhällsproblem som akut måste stoppas. Lagstiftning och fördömande genom rättskipning är betydelsefulla medel i striden om förändring i jämställdhetsfrämjande riktning. Det finns emelleEvery fifth case of lethal violence in Sweden 2018 was constituted by men’s lethal violence against female partners or formal partners. This kind of violence is a problem of big proportions that needs to be detained now. Legislation and condemnation through the Swedish justice system are important means to achieve change in a gender equal direction. There are however parts of the Swedish criminal
Vid utformningen av rätten att överklaga och prövningen i andra instans finns en mängd aspekter att ta hänsyn till. Dessa ställer på sätt och vis olika krav på prövningens utformning. Detta gäller såväl nationellt som internationellt. Vid utformningen av rätten att överklaga och prövningen i andra instans är det naturligt att landets konventionsåtaganden i form av art. 2 i sjunde tilläggsprotokollWhen forming the right to appeal and the trial in second instance there are a number of aspects to take into account and the different aspects sets, in certain ways, different demands on the form of the trial. This goes both nationally and internationally. When forming the right to appeal and the trial of second instance, it is natural to examine the countries obligations to Art. 2 of the Seventh
I Sverige görs en åtskillnad mellan begränsat skattskyldiga skattesubjekt och obegränsat skattskyldiga skattesubjekt. Den person som är obegränsat skattskyldig är som huvudregel skattskyldig för alla sina inkomster, oavsett om inkomstens källa är i Sverige eller något annat land. Den person som är begränsat skattskyldig, däremot, är skattskyldig i Sverige enbart för vissa inkomster som har sin kälSweden distinguishes between limited taxable persons and fully taxable persons. A fully taxable person is, generally, taxable for all their worldwide income. A limited taxable person, on the other hand, is taxable in Sweden only for certain income derived from Sweden. A person that is not fully taxable, is a limited taxable person. Fully taxable persons are those who are domiciled in, stay regular
Title Servitization in Manufacturing Firms: Exploring Possible Relations Between the Product-Service Systems Offered by Highly Servitized Manufacturing Firms and the Market Environments in which they Operate Authors Edvin Magneteg Max Parkosidis Supervisors Ola Alexanderson, Faculty of Engineering (LTH), Lund University Stefan Calling, ASSA ABLOY Entrance Systems Background In recent years, an
In recent years, there has been a surge in attention towards biodegradable polymer films, driven by the growing environmental awareness concerning the harmful effects of petroleumbased plastics. The maize protein zein, a by-product from wet milling processes, has shown potential to work as hydrophobic coating. The aim of this study has therefore been to find the most promising process conditions f
3D city models are valuable tools for visualization and analytical purposes in the urban environment. A popular format for city models is CityGML, an open data model that can be used for storage and exchange of 3D city models. However, using city models based on CityGML has appeared to be a challenge as there is a limited number of software applications that are able to read them. Complexity in Ci
Self-levelling flooring compounds (SLCs) are mainly used on concrete floors. Their purpose is to smooth the floors and make them horizontal. The fact that they are self-levelling means that they spread out like water over the floor before hardening to a horizontal layer. Some of them are also advertised as being self-desiccating. A quote from a big manufacturer on the Swedish market regarding thei
Solidariskt ansvar har under lång tid tillämpats i Svensk lag i fall då flera personer ska svara för ett skadestånd. Det solidariska ansvaret innebär att en skadelidande kan kräva ut hela skadeståndet från endera skadevållaren. För att detta inte ska leda till orimliga slutsatser finns det dock tillfällen vid jämkade skadestånd då det solidariska skadeståndet ej används. I vilka jämkningsfall ett Joint and several liability has been used in Sweden for a long time when several people are held responsible for damages. Joint and several liability entails that a creditor can demand full compensation from any of the defendants. In order for this rule not to result in absurd consequences, there is an exception where mitigation of damages can lead to several liability instead. However, to what ex
Development of environmentally friendly and cost-efficient energy sources has been a challenge for modern society since long ago. Sunlight is an infinite and costless source of energy on Earth, so it would be an enormous advantage to efficiently harvest and transform it into electrical energy used in our everyday life. In nature the process, which converts light energy into chemical energy, is cal
This report is about the housing situation in Manila, capital of the Philippines. 25% of the inhabitants in this mega city live in informal settlements, often on places unsuitable for living. The target area of this paper is Baseco, a large slum area near the outlet of Pasig River and home to 47 000 people according to the 2002 census. Among its many problems including overpopulation and poverty i
Ett koordinerat samarbete och tydlig kommunikation utgör grunden för en välfungerande projektering av ett byggprojekt. I det traditionella tillvägagångssättet utförs arbetet sekventiellt, där projektet passerar mellan de inblandade parterna i turordning. Detta linjära arbetsflöde leder ofta till fragmentering av projektdata och svårigheter att bibehålla en gemensam förståelse mellan inblandade parA coordinated collaboration and clear communication forms the foundation for a well-functioning construction project. In the traditional approach, the work is carried out sequentially, where the project is passed on from one involved party to the next. This linear work flow often leads to fragmentation of work data and difficulties in maintaining a common understanding of the project, which in tur
