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Instrumental analysis in metabolomics has proven to be a challenging topic due to metabolites having a wide spectrum of physiochemical properties and concentrations. The more conventional techniques in metabolomics include gas chromatography and liquid chromatography coupled with mass spectrometric (MS) detection. In most cases these techniques provide methods that are adequate for metabolomic res
In the ongoing library debate part of the focus has been on youth in libraries and how many libraries find them to be a challenging group to work with due to some occurring disturbances. In some cases the youth sections start to lean towards being youth recreation centers. Youth need somewhere to be that isn’t home or school and since there aren’t many open, free of cost public spaces, and many ci
Bostadsbristen slår hårdast mot dem som redan står längst ifrån bostadsmarknaden. Unga, nysvenskar och äldre har fått det svårare att få sina bostadsbehov tillgodosedda. Det svenska bostadsbyggandet har sedan år 2006 varit lågt i förhållande till befolkningsutvecklingen (Boverket 2015:a). Effekterna av ett lågt bostadsbyggande är bland annat en ökad trångboddhet, osäkra boendeförhållanden, svarthaThe effects of a housing shortage will be hardest on those groups, who are far from being a part of the housing market. It is becoming more and more difficult for young adults, immigrants and elderly to find a solution for their housing needs in Sweden. Since 2006, the rate of construction of housing in Sweden has been relatively low compared to the population growth rate (Boverket 2015:a). The ef
BACKGROUND: Pregnancies occurring after bariatric surgery are associated with various perinatal complications. However, there may be differences in the type of perinatal complications occurring after different methods of bariatric surgery. The aim of the current study was to compare adverse perinatal outcomes in pregnant women following Roux-en-Y Gastric Bypass (RYGB) vs. Sleeve Gastrectomy (SG).M
Background: Opioid substitution treatment (OST) populations are aging and have increased mortality and somatic morbidity compared to general populations internationally. While OST patients have poor self-rated physical health and unmet healthcare needs, documented healthcare utilization has been sparsely investigated. The aim of this study was to assess registered healthcare utilization for somati
Background: Increased solar and geomagnetic activity (SGA) may alter sympathetic nervous system activity, reduce antioxidant activity, and modulate physiochemical processes that contribute to atmospheric aerosols, all which may reduce pulmonary function. Objectives: Investigate associations between forced expiratory volume at 1 s (FEV1) and forced vital capacity (FVC) with SGA, and assess whether
Background: Abiraterone acetate (AA) is an androgen biosynthesis inhibitor shown to prolong life in patients with castration-resistant prostate cancer (CRPC) already treated with chemotherapy. AA treatment results in dramatic declines in prostate-specific antigen (PSA) in some patients and no declines in others, suggesting the presence of molecular determinants of sensitivity in tumors. Objective:
Introduction: Cycling as a means of transport or recreational activity is increasing in popularity in Ireland. However, increasing numbers of cyclists may lead to an increased number of bicycle collisions and fatalities. The Road Safety Authority is the statutory body for road safety in Ireland but uses police data alone to collate cycling collision statistics. This may lead to an underestimation
The ongoing multi-country human monkeypox (HMPX) outbreak was declared as a public health emergency of international concern. Considering the key role of healthcare workers (HCWs) in mitigating the HMPX outbreak, we aimed to assess their level of knowledge and their confidence in diagnosis and management of the disease, besides the assessment of their attitude towards emerging virus infections fro
Pediatric central nervous system (CNS) tumors represent the most common cause of cancer-related death in children aged 0–14 years. They differ from their adult counterparts, showing extensive clinical and molecular heterogeneity as well as a challenging histopathological spectrum that often impairs accurate diagnosis. Here, we use DNA methylation-based CNS tumor classification in combination with
The recovery of ‘waste heat’ from industrial and urban processes could meet a significant share of heating demands in urban and semi-urban areas. Replacing conventional heat sources in district heating (DH) systems with recovered heat could decrease primary energy inputs in a sector that globally relies to 90% on fossil fuels. Yet, despite the environmental, social, and economic benefits of waste
The rate of global urbanization in the 21st century has been unprecedented especially in the African and the Asian continents. Urbanization typically causes a removal of natural vegetation and replacement of same with impervious and non-evaporative urban materials with high heat capacity and low solar reflectivity. The alteration of the natural land cover due to urbanization causes a change in the
Kommuner sköter enligt 14 kap. 2 § regeringsformen lokala och regionala angelägenheter av allmänt intresse på den kommunala självstyrelsens grund. Vad som är kommunala angelägenheter regleras av kommunallagen och specialförfattningar som exempelvis socialtjänstlagen och ordningslagen. Syftet med uppsatsen är att undersöka gränserna för det kommunala beslutsfattandet och hur kommunala beslut kan koMunicipalities manage according to Chapter 14. Section 2 regeringsformen local and regional affairs of general interest on the basis of municipal self-government. What is municipal affairs is regulated by the Municipal Act (kommunallagen) and special regulations such as the Social Services Act (socialtjänstlagen) and the Ordinance Act (ordningslagen). The purpose of the thesis is to investigate th
Uppsatsen syftar till att kritiskt granska reglerna om tvångslikvidation vid kapitalbrist som återfinns i 25. kap 13-20a §§ ABL för att utröna om regleringen utgör ett effektivt och adekvat skydd för bolagets borgenärer. Utredningen består i huvudsak av en granskning av vad tvångslikvidation vid kapitalbrist innebär, den handlingsprocedur som följer av kapitalbristreglerna, samt de rättsverkningarThis thesis examines the regulation on involuntary liquidation due to capital deficiency in Chapter 25, Sections 13-20a of the Swedish Companies Act (Sw. Aktiebolagslagen (2005:551)). The purpose of the thesis is to determine whether the regulation constitutes an effective and adequate protection for the company's creditors. The thesis consists of an examination of what involuntary liquidation
This study examines landslide occurrence and post‑landslide recovery dynamics in Nyungwe Forest Reserve, Rwanda, using a combination of multi‑temporal landslide mapping, environmental and geomorphological predictor analysis, and an assessment of the Tropical Moist Forest (TMF) product. A landslide inventory covering the period from 2000 to 2024 was produced using high‑resolution optical imagery. T
Purpose: This paper aims to explore and examine how companies have reacted to suddenly occurring crises in the 21st century. The paper will investigate how companies have adapted – or stayed in hiding – during the COVID-19 pandemic, and how this has impacted their corporate brand identity and their core values. The paper will introduce a new framework to be used for assessing the strategic approac
The emerging effects of man-induced climate change lead to difficulties in the planning of urban development. This study seeks to investigate how the stormwater pipe system in Trelleborg, Sweden, responds to climate change in terms of sea level rise and rainfall. The timeframe of this study extends to the year 2100 and the emission scenario RCP8.5 was employed. Twelve scenarios were formulated to
Motor complications in Parkinson's disease (PD) are associated with long-term oral levodopa treatment and linked to pulsatile dopaminergic stimulation. l-dopa-carbidopa intestinal gel (LCIG) is delivered continuously by percutaneous endoscopic gastrojejunostomy tube (PEG-J), which reduces l-dopa-plasma-level fluctuations and can translate to reduced motor complications. We present final results of
A large number of studies have shown that friends’ smoking behavior is strongly associated with an individual’s own risk for smoking. However, few studies have examined whether other features of social networks, independently or conjointly with friends’ smoking behavior, may influence the risk for smoking. Because it is characterized by the growing importance of friendship networks, the transition
