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AbstractAsthma is a chronic disease that affects approximately 300 million people worldwide, and the prevalence is increasing. It has become clear that asthma is a highly heterogeneous disease, with overlapping symptoms but with diverse immunopathology and clinical phenotypes. Also, a significant proportion of asthma patients have remaining symptoms despite treatment. In addition to different phen
Taxation is a key activity of any state and a constant point of political struggle. The structure of taxation is continuously changing and evolving, and its size has grown dramatically during the last two hundred years. Many of the cross-national patterns we observe today are the result of centuries old conflicts and challenges, hence we need to take history into account if we want to understand c
MASTER (MAnaging Speeds of Traffic on European Roads) aims to provide recommendations for speed management strategies and policies and to elaborate guidelines for the development of innovative speed management tools. Within the framework of the project, field trials with a car equipped with a speed limiter were carried out in three “regional typical” European countries: Sweden, the Netherlands, an
Popular Abstract in English Disasters continue to affect urban populations and housing infrastructure. They are intensified by extreme weather events caused by climate change. This situation has made the creation of synergies between climate change adaptation (CCA) and disaster risk management (DRM) urgent. Despite their similarities and the recognised need to unite CCA and DRM efforts, the fieldsAn increasing number of disasters continue to affect urban populations and housing infrastructure. The overwhelming majority of them have been caused by climate-related events. This situation has made the creation of synergies between climate change adaptation (CCA) and disaster risk management (DRM) urgent. Despite the recognised need to unite CCA and DRM efforts, the fields remain separate. Furt
AIMS/HYPOTHESIS: Obesity during pregnancy increases offspring type 2 diabetes risk. Given that nearly half of women of child-bearing age in many populations are currently overweight/obese, it is key that we improve our understanding of the impact of the in utero/early life environment on offspring islet function. Whilst a number of experimental studies have examined the effect of maternal obesity
I Sveriges centrala inland finns det allt från enstaka sanddyner till stora dynfält som täcker mer än 10 km2. Dessa dynfält passerar dock oftast obemärkt i landskapet på grund av det oftast markanta vegetationstäcke som fixerar dessa dyner. De är dock värdefulla för att kunna återskapa forna tiders klimat och vindmönster, men tyvärr har förhållandevis lite forskning angående dessa dyner bedrivits In the Swedish inland there are aeolian deposits present, ranging from scattered single dunes to dune fields of more than 10 km2. These dune fields often pass unnoticed since they presently are covered by vegetation. However, they contain a rich palaeoenvironmental archive. Only a few research papers have been published regarding these aeolian deposits during the last 90 years. The primary scope o
This report describes how the work has been conducted in the project “A National Strategy for Standardisation of Digital Information Management within the BuiltEnvironment” (further on denoted NSS). This report describes the project background, aim, objective, methodology, schedule, organisation, and identified areas and processes that have been the basis for the development of the initial three-y
Objectives: The main goal of the COVIDENZA trial is to evaluate if inhibition of testosterone signalling by enzalutamide can improve the outcome of patients hospitalised for COVID-19. The hypothesis is based on the observation that the majority of patients in need of intensive care are male, and the connection between androgen receptor signalling and expression of TMPRSS2, an enzyme important for
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with mutations in the NPM1 gene occurring in almost one third of all cases. The ability to detect residual leukemia below the resolution of conventional microscopy is crucial for evaluation of relapse risk after therapy. In principle, this can be achieved by measuring residual disease (MRD) with two different approac
Att vatten övergår till ånga när man hettar upp det är ett välkänt fenomen, men även materia som bygger upp atomkärnor kommer att genomgå en fasövergång om den hettas upp tillräckligt mycket. Det som då bildas är ett kvark-gluonplasma (QGP), en exotisk form av materia där atomkärnans minsta beståndsdelar - kvarkar och gluoner - mer eller mindre rör sig fritt, vilket radikalt skiljer sig från vanliBy colliding heavy nuclei at high energies, which is done at RHIC and the LHC, a strongly interacting Quark Gluon Plasma (QGP) is created. This manifests itself through several different signatures, which until recently was thought to uniquely probe the QGP. Recently, however, similar signatures have been observed also in small systems, such as pp collisions with high charged-particle multiplicity
Background Vaccine effectiveness against COVID-19 needs to be assessed in diverse real-world population settings.Methods A cohort study of 805 741 residents in Skåne county, Southern Sweden, aged 18-64 years, of whom 26 587 received at least one dose of the BNT162b2 vaccine. Incidence rates of COVID-19 were estimated in sex- and age-adjusted analysis and stratified in two-week periods with substan
A number of global megatrends, such as self-driving technology, elec- trification of vehicles, ICT, CSR and a lot of other social and political trends are currently impacting the Swedish truck freight system. Identi- fications of these trends and preparedness for the potential impact they will have on the future truck freight system will be paramount for both incumbents and new actors in this system
Power systems operate at a specific frequency and constantly require a balance between production and consumption of electricity in order to maintain the frequency within a certain interval. Larger frequency deviations can cause blackouts or damage equipment connected to the grid. Balancing functions that stabilise the grid are referred to as \textit{ancillary services}, which in Sweden include th
För att se vilken inverkan regnets intensitet har på avrinningskoefficienten gjordes en litteraturstudie samt beräkningar i Excel. Litteraturstudien visar att de tabellerade värdena på avrinningskoefficienten är framtagna genom en undersökning där ett formulär sändes ut till privata och offentliga kontor i USA där de angav vilka värden på avrinningskoefficienten de brukar använda. Resultatet är prIn order to increase the knowledge regarding how the runoff coefficient varies with increased rainfall intensity, a literature study and calculations in Excel were conducted. The background to how the tabled values of the runoff coefficient have been determined was found to be a book based on an assembly of answers to a survey collected from different companies in USA. The book is called Design an
In pursuit of a sustainable society, the bike possesses a central importance. It is important that the bike lanes meet the needs in terms of accessibility and safety. In the Netherlands, the UK and Denmark already exists so-called super cycle routes, which have proven to be very successful, as they contributed to the increased cycling, and at same time improved accessibility and comfort for the cy
A common approach to treat respiratory diseases is with adhesive powder mixtures. These are dispersed into an aerosol upon inhalation. It has been found that the performance of such mixtures can be improved by adding fine particle lactose, but exactly why is yet to be established. Several theories have been proposed by previous studies, but the fundamental mechanism is still unknown. This study w
De barn och ungdomar som nyligen kommit till Sverige är ingen enhetlig grupp utan består av barn med olika ursprung, som också har olika skolbakgrund. Under senare tid har flyktingströmmen till Sverige ökat markant och vi har under 2015 tagit emot ca 50 000 barn i åldern 7-17 år. Utöver dessa barn har även ett stort antal EU-migranter kommit till Sverige i enlighet med den fria rörligheten. Vad soThe children and adolescents who recently have come to Sweden are not a homogenous group. The group consists of children with different origins and they also have different educational background. Recently the level of refugees coming to Sweden has risen significantly, and during 2015 Sweden have received approximately 50 000 refugee children in the ages 7- 17. Besides the refugee children there a
Miljöbalkens övergripande mål är att uppnå hållbar utveckling enligt balkens portalparagraf. Begreppet består av tre element: ekologisk, ekonomisk samt social hållbarhet. Hållbar utveckling ska genomsyra tillämpningen av hela balken. För att hållbar utveckling ska förverkligas krävs att underliggande delmål beaktas. Inom ramen för det övergripande målet finns 16 miljökvalitetsmål fattade av riksdaThe main objective of the Environmental Code (miljöbalken) is to achieve sustainable development, according to the code’s initial paragraph. The objective of sustainable development consists of three pillars: ecological, economic and social sustainability. Sustainable development is supposed to permeate and influence the application of the entire Environmental Code. In order to achieve the goal of
The interest in the production of 3D geo data has in recent years greatly increased, and many performers are interested in making use of 3D geo data for including urban design, planning, analysis, city models and web services. The use of 3D geo data can lead to an increased communication with the citizens thought interactive web maps. For example the user can slide around in a planned district or
