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Four researchers from the Centre receive grants from the Swedish Research Council Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These co
Increasing CO₂ emission is considered as the main reason for global warming in the world. One of the reasons for producing CO₂ is using of fossil-based materials in the construction projects. This study intends to assess the using bio-based materials instead of fossil-based materials for the thermal insulation layer of the external walls and roofs. Another focus of this project is using green conc
Abstract: For patients with locally advanced head and neck tumours or other defects, the preferred curative treatment is extensive reconstructive surgery using free microvascular flap(s), oftentimes followed by postoperative radiotherapy. The procedure offers superior functional and aesthetic advantages, but the treatment course is long and complex and burdened with a significant risk of complicat
Background: Acute kidney injury (AKI) is a serious complication after lung transplantation, but the reported incidence varies in the literature. No data on AKI have been published from the Swedish lung transplantation program. Methods: The aim of our study was to investigate the incidence, perioperative risk factors, and effects of early postoperative acute kidney injury (Kidney Disease Improving
BACKGROUND: Minimally invasive surgery is rapidly expanding globally, yet there is insufficient knowledge of how to scale this technology safely and equitably across diverse health systems. We aimed to identify health-system factors associated with safe implementation of minimally invasive surgery globally, using minimally invasive cholecystectomy as a tracer procedure.METHODS: We conducted a mult
Driven av en kärnnyfikenhet på förändringens och förändringssökandets politiska psykologi i motsats till kontinuitet och status quo-upprätthållande i världspolitiken, åtar sig denna avhandling att undersöka den ontologiska dynamiken och de psykiska drivkrafterna bakom revisionistiskt beteende i internationella relationer (IR). Genom att identifiera sig med en konstruktivistisk tendens till "konstiDriven by a core curiosity about the political psychology of change and change-seeking as opposed to continuity and status quo-keeping in world politics, this thesis undertakes to investigate the ontological dynamics and psychic drivers of revisionist behavior in International Relations (IR). Identifying with a constructivist tendency for “constitutive theorizing,” it deploys—and in so doing, theo
Suddträsket är ett internationellt erkänt våtmarksområde av stor betydelse som ligger beläget längst Vita Nilen i Sydsudan. Våtmarkens unika ekologiska miljöer har lett till skapandet av flera naturskyddsområden för bevarandet av de naturliga habitaten och dess ovärderliga ekosystemtjänster. Tillsyn av skyddsområdena bidrar i allmänhet till deras bevarande. Däremot har de pågående politiska osäkerThe Sudd wetland, situated along the White Nile in the Republic of South Sudan, is recognized internationally for its unique environmental features. The distinctive ecological characteristics have resulted in the creation of numerous nature reserves in efforts to conserve the habitats and ecosystem services provided. Monitoring changes within the nature reserves usually contributes to their protec
Lipids in the presence of a solvent can through the process of self-assembly form a number of phases referred to as Lipid Liquid Crystalline (LLC) phases. The inverse hexagonal, inverse bicontinuous cubic phases and sponge phase are examples of LLC structures that have been studied and used in drug delivery settings or food applications. For this project the focal point will be the sponge (L3) pha
Introduction Episodic memory allows us to revisit our past and recollect inter-related elements that characterize life events (Tulving, 1983). When forming such relational memories, we only apprehend a small part of our visual field in full acuity at a time. This limitation is overcome by shifting visual attention over a sequence of eye movements. We bind these visual “samples” of the world into
AbstractThe overall aims of this thesis were to use echocardiography to non-invasively, delineate early structural andfunctional changes following orthotopic heart transplantation (OHT), and to define reference values in the contextof gender and bridging with mechanical circulatory support.Several factors might affect myocardial function in OHT patients rendering the use of normal values fortranst
Objective: To develop a model and methodology for predicting the risk of Gleason upgrading in patients with prostate cancer on active surveillance (AS) and using the predicted risks to create risk-based personalised biopsy schedules as an alternative to one-size-fits-all schedules (e.g. annually). Furthermore, to assist patients and doctors in making shared decisions on biopsy schedules, by provid
Background: Short-acting β2-agonist (SABA) bronchodilators help alleviate symptoms in chronic obstructive pulmonary disease (COPD) and may be a useful marker of symptom severity. This analysis investigated whether SABA use impacts treatment differences between maintenance dual- and mono-bronchodilators in patients with COPD. Methods: The Early MAXimisation of bronchodilation for improving COPD sta
Background: Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functiona
Background: Although gaming is a common arena where children socialize, an increasing number of children are exhibiting signs of problem gaming or internet gaming disorder. An important factor to the development of problem gaming is parent-child relationships. A cognitive behavioral therapy–based form of treatment, labeled relapse prevention, has been developed as a treatment for child and adolesc
Acute respiratory distress syndrome (ARDS) is a life-threatening, high mortality pulmonary condition characterized by acute lung injury (ALI) resulting in diffuse alveolar damage. Despite progress regarding the understanding of ARDS pathophysiology, there are presently no effective pharmacotherapies. Due to the complexity and multiorgan involvement typically associated with ARDS, animal models rem
The haematopoietic stem cell (HSC) is a somatic stem cell essential for life long haematopoiesis; HSCs have the capability to differentiate into all mature types of blood cells and can also undergo self-renewal to maintain their own numbers. They also have the potential to reconstitute a complete haematopoietic system following HSC transplantation, also known as bone marrow transplantation, which
Objectives: The aim of this study was to investigate genetic outcomes, analyze the family experience, and describe the process of implementing genetic sequencing for children with profound sensorineural hearing loss (SNHL) at a tertial audiological center in southern Sweden. Design: This is a prospective pilot study including eleven children with profound bilateral SNHL who underwent cochlear impl
BACKGROUND: Swedish policy states that older adults should be able to age safely with continued independence and lead active lives. However, this plays out differently in different Swedish municipalities depending upon degree of demographic change, globalization, and urbanization. Internationally, older adults living in disadvantaged areas have worse physical and mental health, activity restrictio
Cloud computing has quickly grown to become an essential component in many modern-day software applications. It allows consumers, such as a provider of some web service, to quickly and on demand obtain the necessary computational resources to run their applications. It is desirable for these service providers to keep the running cost of their cloud application low while adhering to various perform
In medical research and within the field of Biology, it is important to find effective tools for probing and manipulating cells, as well as tools for detecting biomolecules. These tools should be sensitive, with high specitivity, and, if aimed at interacting with cells, they should be minimally invasive. In this thesis, I investigated the potential of various nanotools for these purposes. Specific
