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Popular Abstract in Swedish Bakgrund - Glutenintolerans (celiaki) är en vanlig kronisk tunntarmssjukdom som drabbar 1% av befolkningen och beror på att man inte tål ämnet gluten som förekommer i vete, korn och råg. Celiaki är delvis ärftligt och förekommer i alla åldrar, men upptäcks framför allt hos barn. Intoleransen mot gluten orsakas av en immunologisk reaktion mot tunntarmens slemhinna som efCeliac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. As a consequence

The glycosphingolipid (GSL) antigens in the clinically important P1PK and GLOB blood group systems are present on erythrocytes as well as other tissues and are so-called histo-blood group antigens. Blood group antigens of carbohydrate nature are products of enzymes, so-called glycosyltransferases, adding sugars in a step-wise manner to an acceptor substrate. Presence or absence of the P1PK and GLO

In August 2008, Georgia was engaged in an internal armed-conflict with its breakaway region of South Ossetia, which shortly after, grew into a large-scale war with Russian Federation. In the course of the war, hundreds of civilians became victims of the international crimes committed by belligerent sides. Hence, the central issue of my research is a post-conflict justice. In particular, if there e

En mycket vanlig behandlingsteknik vid cancer är strålbehandling. Tekniken har utvecklats snabbt de senaste åren och idag uppnås millimeterprecision för många behandlingsområden. Därmed har behovet av att kunna kompensera för rörelser under behandlingen ökat. I detta arbete undersöktes möjligheten att låta strålgången följa tumören med en teknik som kallas MLC-tracking. Strålbehandling började a"Purpose: To investigate the geometric accuracy of MLC-tracking using a circular field, and to investigate the dosimetric accuracy for inversely optimized arc delivery to a moving target. This is done for two different MLCs and for varying plan complexity. Materials and methods: For investigating the geometric accuracy, a marker was placed on a motion platform while the MLC set to shape a ci

1. The effects and binding characteristics of a series of chimeric galanin-neuropeptide Y (NPY) peptides were examined in various preparations known to contain a predominant population of either Y1 or Y2 receptors for NPY or galanin receptors. 2. NPY suppressed the electrically stimulated twitches of the rat vas deferens (Y2 receptors), while galanin enhanced the electrically stimulated twitches.

The purpose of the thesis is to study whether any special professional norms exist with regard to principals’ leadership of the democratic mission which is presented to the schools. The aim is to identify norms in order to be able to later analyse and understand them. Norms exist in groups of various types, and by using the term “norm” I am addressing the actions of principals, rather than their i

Bilden av Sverige som ett land utan grov organiserad brottslighet har successivt kommit att förändras. Grov organiserad brottslighet är inte längre något som svenskarna enbart associerar med södra Italien och Francis Ford Coppolas kultförklarade film Gudfadern. Som en del av denna utveckling inleddes under 2007 regeringens mobilisering mot grov organiserad brottslighet, vilken i huvudsak har kommiThe self-image of Sweden as a country without organized crime has gradually been changing. Organized crime is no longer something that the Swedes associate with southern Italy or Francis Ford Coppola’s cult film The Godfather. In 2007, the Swedish government initiated a mobilization against organized crime, which in essence came to mean two things. Firstly, the government founded an extensive coop

Konkurrensrätten främjar flera syften, däribland effektiv konkurrens och avtalsfrihet. Vad händer när dessa syften ställs mot varandra? Exempelvis när ett dominant företag väljer att inte leverera en resurs till sina konkurrenter eller andra aktörer på marknaden och den effektiva konkurrensen därför begränsas. Ett sådant beteende kan vara otillåtet, avtalsfriheten till trots. Doktrinen om nödvändiCompetition law promotes several purposes, including that of an effective competition and contractual freedom. What are the consequences when these purposes clash? For example, what happens when a dominant company refuses to supply a certain resource to its competitors with the result of hindering the competition? Such behaviours can be deemed illicit, despite the promotion of contractual freedom.

Ett medlemskap i EU innebär långtgående rättsliga konsekvenser på nationell nivå. Medlemsstaternas suveränitet är emellertid fortfarande relativt oinskränkt på den direkta beskattningens område, vilket följer av att unionen saknar befogenhet på området och medlemsstaterna således åtnjuter exklusiv kompentens. Medlemsstaterna kan fritt utforma sina skattesystem, men den nationella beskattningsrätteAn EU accession involves far-reaching legal consequences on a national level. Nevertheless, the sovereignty of the member states has remained relatively unrestricted in the area of direct taxation. The Union has no remit of competence in the area and the Member States therefore enjoy exclusive competence when it comes to direct taxation. The Member states maintain the right to design their own tax

There has been an increasing interest in wastewater treatment in last decades to reduce human footprint. Primarily, anaerobic technology focused on treatment and stabilization of sludge, but now the tendency is to give it a major role in low cost treatment of high/low strength wastewaters, since anaerobic digestion offers energy generation through gas production. Anaerobic membrane bioreactors (A

Problemformulering: Byggprocessen är idag långsam, kostsam och genererar stora mängder spill och utsläpp. För att kunna möta bostadsbehovet från den snabbt växande befolkningsmängden måste tekniken utvecklas, den måste bli snabbare och mer kostnadseffektiv. Med ny teknik där betongelement tillverkas genom automatiserad och datorstyrd 3D-printning kan eventuellt hela betongbyggnadsprocessen effektiQuestion formulation: The construction process today is slow, costly and generates large amounts of waste and emissions. In order to meet housing needs of the rapidly growing population in a sustainable way, the technology must evolve; it must be faster and more cost-effective. New technology, where concrete is manufactured by automated and computer-controlled 3D-printing, can possibly streamline

Performance measurement system, especially the Balanced Score Card (BSC) is gaining increasing popularity among various kinds of organizations, especially these years more and more non-profit organizations such as: schools, hospitals, labor unions, etc., are putting emphasis on the implementation of performance measure system to improve their practice. It was demonstrated that a great amount of ac

Inhaled corticosteroid (ICS) therapy is central to the long-term management of asthma and is extensively used in the management of chronic obstructive pulmonary disease (COPD). While administration via inhalation limits systemic exposure compared with oral or injected corticosteroids and, therefore, the risk of systemic corticosteroid-related adverse effects, concerns over the long-term safety of

Populärvetenskaplig sammanfattning:En studie publicerad av NASA:s Goddard Institute for Space Studies år 2019 visade att de genomsnittliga globala temperaturerna under de senaste fyra åren (2015-2018) var de högsta som någonsin registrerats i människans historia. Den nyheten passar väl in i de alarmerande prognoserna om global uppvärmning, och kräver snabba och radikala handlingar. Att studera “teInnovative design and materials are needed to satisfy the demand for efficient and scalable devices for electronic and opto-electronic applications, such as transistors, LEDs, and solar cells. Nanostructured III-V semiconductors are an appealing solution, combining the excellent functional properties of III-V materials with the flexibility typical of nanostructures, such as the nanowires (NWs) stu

The realization that the extraction and combustion of fossil fuels is having serious effects on the environment and the climate, together with the ever-growing need for fuels, has led to the development of the concept of the biorefinery. Biorefineries are refineries in which fossil resources, such as oil, are replaced by renewable biomaterials to produce biofuels and biochemicals. Non-edible bioma

Background: Few tools evaluates quality of movements in individuals with knee osteoarthritis (OA). The Test for Substitution Patterns (TSP) is developed to measure the ability to perform five functional movements regarding postural control and altered movement patterns (1). TSP is validated and reliable in individuals with anterior cruciate ligament injury, but has not yet been evaluated in indivi

Background: Vascular-targeted photodynamic therapy, a novel tissue-preserving treatment for low-risk prostate cancer, has shown favourable safety and efficacy results in single-arm phase 1 and 2 studies. We compared this treatment with the standard of care, active surveillance, in men with low-risk prostate cancer in a phase 3 trial. Methods: This randomised controlled trial was done in 47 Europea

Background and aim: Due to an increasingly ageing population, the number of hip fracture patients, often with multiple chronic diseases and multiple pharmacotherapy, is set to rise. The high risk of adverse outcomes that hip fractures lead to in older individuals is well described, including high first-year mortality. This thesis aim to improve our knowledge of older hip fracture patients’ treatme

Background: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable by their likely biological action as erythrocytic (also associated with erythrocyte traits) or glycemic (associated with

Background: Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is usually a self limited condition, it is associated with wheezing syndromes in late childhood. The rationale for the use of salbutamol