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Although biologics have revolutionized psoriasis treatment, they pose a significant burden on the healthcare budget. With the wide range of biologics available and the increasing number of biosimilars, insights into the real-world cost per responder (CPR) are required. Therefore, this study aims to evaluate the real-world CPR of adalimumab, ustekinumab, IL17-and IL23-inhibitors, incorporating both
Introduction: Despite therapeutic achievements in haemophilia care, there is still the need to monitor and define personal treatment outcomes and document results to achieve the best possible care. Hence, a need for unbiased, timely and comprehensive real-world information exists to support informed shared decision-making regarding treatment and care. Aim: To describe a medical device for people l
BackgroundSuicide is a leading cause of premature mortality worldwide, but the impact of system-level mental health resources remains unclear despite the central role of psychiatric inpatient care and declining bed capacity. Prior research has yielded inconsistent findings with limited control for confounding. We aimed to estimate the effect of psychiatric inpatient bed availability on suicide mor
Objective: To assess the feasibility and acceptability of HPV self-sampling in Arusha region, northern Tanzania, because the ability for women to self-collect HPV samples can help reduce the number of health facility visits and improve cervical cancer screening coverage rates. Methods: We conducted a facility- and community-based cross-sectional study among 350 women aged 25–55 years in Arumeru di
BackgroundSelf-regulation of payment disclosure by pharmaceutical industry trade groups is a major global approach to increasing transparency of financial relationships between drug companies and healthcare professionals and organisations. Nevertheless, little is known about the relative strengths and weaknesses of self-regulation across countries, especially beyond Europe. To address this gap in
Health professions education places significant emphasis on learning in the clinical environment. While experiences of workplace learning have been extensively investigated, practices of workplace learning explored through field work have been less utilized. The theoretical framework of teaching and learning regimes acknowledges aspects of power and conflict in its consideration of what guides tea
Background: Low birth weight (LBW) is an important risk factor for childhood morbidity and mortality, consequently an important public health concern. Aim: This study aims to identify significant socio-economic and nutritional determinants associated with LBW in India. Materials and Methods: Data from 2005 to 2006 National Family Health Survey-3 (NFHS-3) of India was analyzed. A total of 20,946 wo
Objectives To assess whether recommendations of individually oriented lifestyle interventions (IOLIs) in guidelines from the National Institute for Health and Care Excellence (NICE) were underpinned by evidence of benefit, and whether harms and opportunity costs were considered.Design Cross sectional survey.Setting UK.Data sources NICE guidelines and supporting evidence.Eligibility criteria All NI
Introduction: Dual bronchodilators are recommended as maintenance treatment for patients with symptomatic COPD in the UK; further evidence is needed to evaluate cost-effectiveness versus monotherapy. Cost-effectiveness of umeclidinium/vilanterol versus umeclidinium and salmeterol from a UK healthcare perspective in patients without exacerbations in the previous year was assessed using post hoc EMA
Background/Aim: Cervical cancer incidence and mortality has decreased after introduction of national screening in Sweden, but women with drug use disorders (DUD) are less likely to participate in screening programs. We aimed to investigate cervical cancer incidence and mortality among women with DUD compared to the general female population in Sweden. Methods: We conducted a cohort study based on
The SAIRLA-supported AFRINT IV project has been collecting data on agricultural intensification from23 farming communities in seven regions in Malawi, Tanzania and Zambia since 2008. Policies in allcountries have a strong focus on maize intensification and also target women as recipients ofsubsidised farm inputs. During this time, data on maize shows that only in the Zambian region hasthere been a
Background: The aim of this study was to identify predictors of outcome after septoplasty in 888 patients from the Swedish National Septoplasty Register. Methodology: This is an observational register study analysing data from patients undergoing septoplasty in Sweden between 2015 and 2016. The patients reported severity of nasal obstruction (mild, moderate, severe) pre- and again 12 months postop
Purpose: To compare experiences for adverse events, especially sexual abuse, and mental health in a group of high school students in out-of-home care with a representative sample of peers of the same age and similar educational attainment living with their parents. Materials and methods: A sample of 5839 students in the third year of Swedish high school, corresponding to a response rate of 59.7%,
Assessment of breast density at the point of mammographic examination could lead to optimized breast cancer screening pathways. The onsite breast density information may offer guidance of when to recommend supplemental imaging for women in a screening program. A software application (Insight BD, Siemens Healthcare GmbH) for fast onsite quantification of volumetric breast density is evaluated. The
BACKGROUND: Studies have shown that patients with depression have higher rates of coronary heart disease (CHD) than people in the general population. However, large-scale population-based data on incidence rates of CHD in people with depression are needed. This study analyzed whether hospitalization for depression predicts CHD in men and women after accounting for socioeconomic status and geograph
Society relies on the continued operation of software systems, from healthcare to social media platforms. These systems can be engineered to be highly reliable, but complexity assures surprise. People have the ability to manage this complexity, filling gaps in design by recognizing, diagnosing and correcting anomalies. Rarely can surprises be managed by individuals alone. When engaged in anomaly r
My master degree project started with an open brief, setting out to explore new possibilities within healthcare in relation to the benefits of IoT. By looking at medical trends, cutting edge diagnostic technologies, hypothesis about the future and by interviewing patients and medical personnel a couple of interesting project directions emerged. A decision was made to focus on prevention and one to
Aim: The aim of this study was to describe the compliance to Swedish guidelines in alcohol-based handrub (ABH) and glove use in healthcare workers (HCWs) caring for intensive care patients. It further aimed to compare the compliance of ABH and glove use between different groups of HCWs as well as between different types of intensive care procedures.Background: Nosocomial infections are a worldwide
Since the early 2000s, the issue of ‘honour-based violence’ has sparked significant discussions in Sweden, leading to governmental and civil efforts to combat this form of violence. An essential intervention highlighted in these efforts is improving knowledge among professionals in sectors such as social and healthcare, schools, and the judicial system. Recently, a new platform has emerged, offeri
Popular Abstract in Swedish Läkemedelsanvändning är en av sjukvårdens viktigaste behandlingsmetoder för att bota och lindra sjukdom. Samtidigt kan läkemedelsanvändning innebära risker. Det finns en risk för att patienterna får biverkningar av sina läkemedel, att läkemedlen fungerar mindre bra tillsammans och att effekten därmed upphör eller förstärks. Vidare finns det risk för att läkemedlen inte Background: There are differences in drug use depending on non-medical factors such as age, gender and socioeconomic status. The combined effect of these factors, with adjustment for multimorbidity, is highly relevant to study to ensure equality in drug use. Objectives: 1. To examine drug use related to age, gender, income and education after adjustment for multimorbidity, in an entire adult popul
