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The incidence of Human Papillomavirus positive (HPV+) tonsillar cancer has been sharply rising during the last two decades. Myeloid cells represent an appropriate therapeutic target due to their ability to orchestrate antigen-specific immunity within the tonsil, the availability of viral antigens, and the proximity of the tumor and the underlying lymphoid tissue. However, the interrelationship of
Objectives: Type I interferons (IFNs) are central and reflective of disease activity in systemic lupus erythematosus (SLE). However, IFN-α levels are notoriously difficult to measure and the type I IFN gene signature (IGS) is not yet available in clinical routine. This study evaluates galectin-9 and an array of chemokines/cytokines in their potential as surrogate markers of type I IFN and/or SLE d
CONTEXT: Turner syndrome (TS) is the most common chromosomal aberration in women; it is the result of structural or numeric abnormalities in the X chromosome. Autoimmune hypothyroidism has been recognized as one of the more prominent disorders associated with TS. OBJECTIVE: This work aimed to study the prevalence of autoimmune diseases in TS. METHODS: A cross-sectional, longitudinal, 25-year follo
Heart failure (HF) and cancer are common diseases among the elderly population. Many chronic diseases, including diabetes mellitus (DM), share risk factors and increase the incidence of HF and cancer. The aim of this study was to investigate if there was an association between HF and the prevalence of haematologic- and solid malignancies. Methods The study population was comprised of almost one mi
Context. Ultra-short-period planets (USPs) are a unique class of super-Earths with an orbital period of less than a day, and hence they are subject to intense radiation from their host star. These planets cannot retain a primordial H/He atmosphere, and most of them are indeed consistent with being bare rocky cores. A few USPs, however, show evidence for a heavyweight envelope, which could be a wat
Recent advances in MRI and increasing knowledge on the characterization and anatomical variability of medial temporal lobe (MTL) anatomy have paved the way for more specific subdivisions of the MTL in humans. In addition, recent studies suggest that early changes in many neurodegenerative and neuropsychiatric diseases are better detected in smaller subregions of the MTL rather than with whole stru
The movement and distribution of ecologically important herbivores such as elephants are of great significance to conservation biologist seeking to understand the fundamental triggers that influence their mobility and the extent to which these parameters affect how they utilize their immediate and surrounding resources. The recent advancement in animal tracking technology coupled with the availabi
Efter att entreprenadavtal ingåtts ges i regelverket om ÄTA-arbeten i AB 04 en omfattande möjlighet att förändra arbetets karaktär och omfattning för säkerställande av en fullgod färdig entreprenad. Detta särskiljer entreprenadavtalet från andra avtal men är en nödvändighet. Omförhandlingsinstitutet kompenserar för ändrade preferenser och yttre omständigheter som kan uppkomma under ett omfattande After a contract of construction is agreed upon the regulations regarding ÄTA-works in AB 04 provides comprehensive opportunities to change the nature and extent of work to ensure an adequate creation. This distinguishes constructive contracts from other agreements, but is a necessity to compensate for changes in developer preferences and external factors which can occur during an extensive and ti
Provtagningar har tillsammans med Lund Tekniska Högskola utförts i Skälderviken för att fastställa den pågående erosion som man tidigare befarat sker i Skäldervikens norra delar. Provresultaten har legat till grund för den erosionsbedömning som tidigare upprättats i Skäldervikens norra delar, och jämförts med nya provtagningar utförda längs med kuststräckan. Studien fokuserar även på hur dynlandskSediment samples have been collected in a collaboration with the faculty of engineering, Lunds Univer-sity in the northern parts of Skälderviken to determine the ongoing erosion that has been observed in earlier studies. The previous tests are the basis of the study and have been correlated with new samples taken along the coast. This study also focuses on how the inland dunes have changed since t
Uppsatsen presenterar de två vanligaste fallen av konkurrerande kollektivavtal. I avsaknad av lag har fråga om konkurrerande kollektivavtal främst reglerats genom rättspraxis. Uppsatsen presenterar hur gränsdragningsavtal tillsammans med prejudicerande domar till viss del har skapat en förutsägbarhet inom rättsområdet konkurrerande kollektivavtal. Det uppstår frekvent frågor om konkurrerande kolleThe essay presents the two most common cases of competing collective agreements. In the absence of law, the legal field of competing collective agreements is primarily regulated through case law. The essay presents how boundary agreement together with precedents produced by the labour court, to some extent has created a predictability in the legal field of competing collective agreement. There are
Agricultural intensification and its effect on spiders and their prey Spiders are abundant predators that can be very useful for biological control, as they eat insects that can damage crops. To study the potential of this group as biocontrol agents it is necessary to understand the trophic relationships and the factors that affect the distribution of both spiders and their prey. For this purpos
In the last decades, the role of warehouses has increased due to wider product range, emphasis on shorter lead times and constant changes in customer demand. The increased demands forces companies to improve their warehousing operations for better service level and decreased costs. Different technology solutions like WMS and RFID are currently available for supporting this improvement. However, th
Det finns olika möjligheter för barn att få komma till tals och det är domstolens skyldighet att se till att barnets åsikter kommer fram i målet. Barn kan för det första få komma till tals i en vårdnadsutredning eller innan snabbupplysningar sker av socialnämnden. För det andra kan barnet också komma till tals inför rätten. I praktiken har det funnits brister i hur tillämpningen av rätten att koFamily law disputes concerning the custody, residence and contact of children have increased in recent years. Judgments made by the court in the resolution of disputes have significant short and long term consequences for the children involved. The child is not a party to the proceedings. Instead the child has a right to be heard and a right to have his or her best interests taken as a primary con
Ett av Sveriges hållbarhetsmål är att senast 2045 inte generera några nettoutsläpp av växthusgaser. För att uppnå detta mål krävs kraftiga åtgärder inom alla sektorer. En av dessa är bygg- och fastighetssektorn som 2018 stod för ca 22 % av Sveriges territoriella utsläpp av växthusgaser. Enbart cementindustrin står för ca 5–7 %. Cirka hälften av klimatpåverkan från moderna flerbostadshus uppkommer One of the main sustainability goals in Sweden is to reduce the nations greenhouse gas emissions to a net-zero level by 2045. This is a national implementation of the Paris- Agreement. To achieve this goal measures need to be taken in all industrial sectors. The construction and real-estate sectors are responsible for about 22 % of Sweden’s yearly territorial greenhouse gas emissions. The cement i
Ett av Sveriges hållbarhetsmål är att senast 2045 inte generera några nettoutsläpp av växthusgaser. För att uppnå detta mål krävs kraftiga åtgärder inom alla sektorer. En av dessa är bygg- och fastighetssektorn som 2018 stod för ca 22 % av Sveriges territoriella utsläpp av växthusgaser. Enbart cementindustrin står för ca 5–7 %. Cirka hälften av klimatpåverkan från moderna flerbostadshus uppkommer One of the main sustainability goals in Sweden is to reduce the nations greenhouse gas emissions to a net-zero level by 2045. This is a national implementation of the Paris- Agreement. To achieve this goal measures need to be taken in all industrial sectors. The construction and real-estate sectors are responsible for about 22 % of Sweden’s yearly territorial greenhouse gas emissions. The cement i
Despite the average 5-year survival rate exceeding 85%, childhood cancer is still the most common cause of disease-related death among children in Sweden. A cancer diagnosis is profoundly traumatic not only for children themselves, but also for the entire family, particularly the primary caregivers, their parents. This project aimed to investigate the extent to which a childhood cancer diagnosis a
Background: Alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) are frequently comorbid and are individually associated with increased risk of suicidal behavior. However, whether their comorbidity exacerbates this risk has not been adequately investigated. Methods: Using a Swedish birth cohort (born 1970–1990; N = 799,203–858,983), we employed Aalen’s linear hazards models to evalu
Accurate, high-resolution global land use and land cover (LULC) mapping is crucial for environmental monitoring, but remains challenging when relying solely on multispectral data. Most existing global LULC mapping studies rely exclusively on multispectral observations, and even those that incorporate synthetic aperture radar (SAR) data often fail to fully exploit the information it provides. SAR p
BackgroundThe Job Demand–Control–Support (JD-C-S) model evaluates how psychosocial work factors affect health and performance. We examined how demographics, job title, and experience influence demand, control, and support among Ghanaian pharmacy staff.MethodsA cross-sectional survey of pharmacy personnel from Tamale and Sagnerigu was conducted using the JD-C-S questionnaire. Demand and control ite
Gastric cancer trends seem to follow improvements in the environment of blue-collar workers, but the etiological role of occupational exposures in gastric carcinogenesis is scantily investigated. The risk of gastric adenocarcinoma in 10 common occupational industries, and particularly the long-term effects of asbestos, organic solvents, impregnating agents, insecticides, and herbicides, were evalu
