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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

The immune processes associated with atherogenesis have received considerable attention during recent years. IgG FcRs (FcgammaR) are involved in activating the immune system and in maintaining peripheral tolerance. However, the role of the inhibitory IgG receptor FcgammaRIIB in atherosclerosis has not been defined. Bone marrow cells from FcgammaRIIB-deficient mice and C57BL/6 control mice were tra

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Retail Knowledge Bank Retail is not just stores. It is a complex system of producers, suppliers, and distributers who all deliver innovative consumer solutions. It is, therefore, essential for retailers to understand how to work with innovation, how to manage innovative relationships, and how to put innovative knowledge into practice. Within the Retail Innovation research theme, our researchers ha

https://www.lusem.lu.se/organisation/research-centres/centre-retail-research-lund-university/retail-knowledge-bank/retail-innovation - 2026-05-27

Retail Knowledge Bank What makes a place a retail destination? What attracts people to stores in different geographical locations? What makes a shopping space attractive, lively, or successful? And why do we prefer shopping in some places to others? The Centre for Retail Research addressed these questions, and more, within the framework of a study entitled Retail Destination. Here you will find re

https://www.lusem.lu.se/organisation/research-centres/centre-retail-research-lund-university/retail-knowledge-bank/retail-destination - 2026-05-27

Course literature is an important part of your studies. You can access the books you need by borrowing them from the library, buying them new or used, or using online resources. Planning ahead can help you save both time and money. Reading listsUniversity programmes and courses often have long reading lists. These are usually available at the start of the course and include the books you are expec

https://www.lunduniversity.lu.se/current-students/student-services-and-support/literature-and-libraries/course-literature - 2026-05-27

A three-session therapist-guided exposure treatment was tested in a consecutive series of eight primary health care patients suffering from panic attacks who specifically used distraction techniques as their primary safety behavior. The Panic Disorder Severity Scale Self-Report (PDSS-SR) was administered at baseline (1-3 weeks before the first session), and 1, 2, and 3 weeks after treatment. Weekl