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Background. Diabetes may be linked to incidence of different tumor diseases and prognosis through various mechanisms such as the disease itself, hyperglycemia, obesity and anti-diabetes therapy. Material and methods. The study includes all women with BC diagnosed in Sweden between 2000 through 2008 (n=54406). The women had no previous cancer diagnosis during the period of 1958-1999. Dates of birth

Our purpose is to critically discuss the quality of governability and scrutiny of, as well as insight in, enterprises owned by local government. Our analysis is empirically grounded in an in-depth case study of one of Sweden’s 10 largest municipalities. The ambition is to highlight troublesome areas and danger zones when it comes to public owning of corporations. We have consulted diverse types of

This master thesis is made in cooperation with Assa Abloy ES in Landskrona, Sweden. The purpose was to investigate the arm system for automatic swing door operators and set up an optimized theoretical model for a new PULL arm system with increased closing torque. The reason why the firm wants to get a more detailed view of the arm system is because of the present prevailing issue with non closing

This thesis is to look into media representation on issues that involve female marriage migrants, in particular, in relation to citizenship, in Singapore, one of the most popular destinations of marriage migration in Asia. Categorized and labeled as “foreign brides” in Singapore, these foreign-born women have long suffered from biased or one-dimensional representation in the local media, particula

The inner tracking system of the ATLAS experiment will be upgraded to a full silicon detector in 2030 for HL-LHC. The new tracking system is called ITk, the Inner Tracker. The ITk requirements include operational efficiency higher than 99% and noise hit occupancy smaller than 0.1%. During the pre-production phase of the ITk project, many short-strip modules were observed to exhibit so-called “Cold

Huntington's disease (HD), a fatal neurodegenerative disorder, is associated with an increased risk of diabetes mellitus. The reason for this is unknown, but considering the functional similarities of neurons and the insulin secreting pancreatic β-cell, pathological mechanisms may be shared by both cell types and account for neuronal as well as endocrine dysfunction. Hence, finding the mechanisms

The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. The PKC family can be subgrouped into classical, novel and atypical isoforms depending on structure and sensitivity to the activators diacylglycero

To better utilize existing wireless systems, they can be combined together to interact and thereby provide better balanced capacity. They can further profit from this by getting their ongoing connection moved from the current system to another. The main issues are to make this move without losing the ongoing connection and to make it seamless, i.e., without the user noticing it. This action of mov

Popular Abstract in Swedish För att ett transplanterat organ ska accepteras av mottagaren behövs immunhämmande läkemedel. Dessa läkemedel dämpar immunförsvaret och förhindrar avstötning av det transplanterade organet. Immunförsvaret har olika sätt att angripa organet, som det uppfattar som kropps-främmande. Idag används olika läkemedel i kombination som behandling mot avstötning. Tyvärr är dessa mTransplantation of vital organs is today a widely used treatment when failure of the organ is a fact. To prevent rejection immunosuppresive treatment must be maintained lifelong, unless transplantation is perfomed between identical twins. Many immunosuppresive agents introduced in clinical practice have been benificial in improving graft survival rates, but adverse effects remains a huge problem t

Brottsoffer är ett ord med många konnotationer som har kritiserats för att antyda hjälplöshet och passivitet. Att kategoriseras som brottsoffer är inte alltid välkommet, men medför likväl fördelar, som till exempel möjligheten att driva en rättsprocess och tillgång till stöd och empati. I Sverige är Riksorganisationen Brottsofferjouren Sverige (BOJ) en viktig aktör när det gäller att ge brottsoffe

Background: Efficient utilization of both glucose and xylose is necessary for a competitive ethanol production from lignocellulosic materials. Although many advances have been made in the development of xylose-fermenting strains of Saccharomyces cerevisiae, the productivity remains much lower compared to glucose. Previous transcriptional analyses of recombinant xylose-fermenting strains have mainl

Background: Human breast tissue undergoes phases of proliferation, differentiation and regression regulated by changes of the levels of circulating sex hormones during the menstrual cycle or aging. Ovarian hormones also likely play a key role in the etiology and biology of breast cancer. Reports concerning the proliferative effects of steroid hormones on the normal epithelium of human breast have