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I och med de utmaningar som mänskligheten idag står inför, med stora klimatförändringar, ökad urbanisering och en global ekonomi kan städer komma att spela en central roll i hållbarhetsarbetet. Det är av vikt att beslutsfattare i städer kan förstå, hantera och styra på ett sätt att städerna utvecklas till hållbara samhällen med hållbara processer. Frågan är hur väl beslutsfattarnas sätt att hanterWith the challenges facing humanity today, with rapid climate changes, an increased urbanization and a global economy, cities can play a central role in sustainable development. It is important that decision-makers in the cities can understand, manage and govern in a way that cities develop into sustainable communities with sustainable processes. The question is how well the decision-makers' w

Instead of investing 145 billion SEK in building a new high speed rail network, much greater value in terms of transport capacity is likely to be found in constructing a new system of tube transport with a travel speed of 600 km/h. The suggested technology does not exist yet. However, research and development is advancing and accepting that a new technology is emerging might be the greatest hurdle

Shedding of epithelium, increased venular permeability, and traffic of activated eosinophils and neutrophils may characterize asthmatic airways. This in vivo study involving briefly anesthetized guinea pigs examines whether epithelial denudation itself affects airway venules and granulocytes. Using an oral probe, a de-epithelialized tracheal zone (0.8 x 30 mm) was produced without bleeding or dama

Popular Abstract in English My PhD thesis has focused on increasing the understanding of the osteoclasts, the cells responsible for degradation of bone, by studying the rare hereditary disease autosomal recessive osteopetrosis (ARO). ARO is present already at birth and is caused by mutations affecting the osteoclasts ability to degrade bone. Non-functional osteoclasts lead to dramatic increases inThis thesis focuses on developing and characterizing novel models for studying osteoclasts with an emphasis on how mutations abolishing osteoclastic acidification affect osteoclast signaling and bone remodeling, as well as how to treat patients bearing these rare mutations. Bone remodeling is under normal circumstances a tightly balanced process where resorption of bone by osteoclasts is followed

Betong är ett av byggsektorns mest använda material, men cementproduktionen står för stora koldioxidutsläpp. Ett sätt att minska klimatpåverkan är att reducera andelen cementklinker genom att använda alternativa bindemedel. Vulkanisk puzzolan från Island, VPI är ett tillsatsmaterial från Heidelberg Materials Cement Sweden som kan användas tillsammans med cement som bindemedel i betong. TillsatsmatConcrete is one of the most widely used materials in the construction sector, but cement production is associated with a significant climate impact. One way to reduce this impact is to decrease the proportion of cement clinker by using alternative binders. Volcanic pozzolan from Iceland, VPI, is a supplementary material supplied by Heidelberg Materials Cement Sweden that can be used together with

Laser-induced photofragmentation fluorescence has been investigated for the imaging of alkali compounds in premixed laminar methane–air flames. An ArF excimer laser, providing pulses of wavelength 193 nm, was used to photodissociate KCl, KOH, and NaCl molecules in the post-flame region and fluorescence from the excited atomic alkali fragment was detected. Fluorescence emission spectra showed disti

Background: Neuropeptides, such as substance P (SP), have long been seen as mediators of widespread continuous airway inflammation, a process known as neurogenic inflammation. However, this has been difficult to demonstrate clinically, suggesting an alternative role for these signaling molecules. Objectives: We sought to examine the role of SP in nasal infection by assessing the release of SP in r

In this paper we call into question the relationship between development, inequality and territory in the current context of globalization and within the framework of public policies designed, supposedly, to benefit those social actors with fewer resources. In order to do this, we focus on a case study in the northeast of the province of Misiones, Argentina. Here tobacco production, forestry and a

In plants the chloroplast thylakoid membrane is the site of light-dependent photosynthetic reactions coupled to ATP synthesis. The ability of the plant cell to build and alter this membrane system is essential for efficient photosynthesis. A nucleotide translocator homologous to the bovine mitochondrial ADP/ATP carrier (AAC) was previously found in spinach thylakoids. Here we have identified and c

This thesis contributes to research on experimental and behavioral economics as well as auction theory. It consists of five papers.The first paper, Differences Attract: An Experimental Study of Focusing in Economic Choice, studies whether individuals' decisions are affected by focus effects. The focus effect suggests that individuals focus more on an attribute that has a larger difference among th

Metamorphic provinces such as the ∼1 ​Ga Grenvillian, ∼400 ​Ma Caledonide and Triassic Qinling Provinces often contain rocks with high-pressure assemblages such as eclogites, which formed at mantle depths in subduction zones. These are evidence of the accretion of terranes by subduction of oceans and collision to form large tectonostratigraphic provinces. The Mesoproterozoic Namaqua-Natal Province

Parkinson’s disease (PD) patients frequently develop cognitive impairment. There is a need for brief clinical assessments identifying PD patients at high risk of progressing to dementia. In this study, we look into predicting dementia in PD and underlying structural and functional correlates to cognitive decline in PD. We included 175 patients with PD, 30 with PD dementia, 51 neurologically health

There is a growing interest in organized self-help housing (OSHH) from both authoriti es and Non Governmental Organizati ons (NGOs) working in the housing sector due to the magnitude of housing problems in developing countries and the challenge of achieving sustainable humansett lements. This paper focuses on the experiences of two NGOs, FUPROVI in Costa Rica and SADEL in Sweden, in facilitati ng

A three-dimensional (3D) direct numerical simulation (DNS) of an experimental turbulent premixed jet flame at high Karlovitz number was studied. The DNS resolution adequately resolves both the flame and turbulence structures. A reduced chemical mechanism for premixed CH4/air flames with NOx based on GRI-Mech3.0 was used, including 268 elementary reactions, and 28 transported species. Consistent po

The aim of this study is to characterize atrial fibrillatory rate (AFR) extracted from a cohort of continuously monitored atrial fibrillation (AF) patients as function of episode duration and onset time. The f-wave signal used to compute the AFR was extracted from a single lead ECG strip of the AF episodes stored in an Implantable Cardiac Monitor (ICM) in a cohort of 99 patients. The f-wave signal

A search for electroweak production of supersymmetric particles is performed in two-lepton and three-lepton final states using recursive jigsaw reconstruction, a technique that assigns reconstructed objects to the most probable hemispheres of the decay trees, allowing one to construct tailored kinematic variables to separate the signal and background. The search uses data collected in 2015 and 201

Rapeseed press cake (RPC), the by-product of rapeseed oil production, contains proteins with emulsifying properties, which can be used in food applications. Proteins from industrially produced RPC were extracted at pH 10.5 and precipitated at pH 3 (RPP3) and 6.5 (RPP6.5). Emulsions were formulated at three different pHs (pH 3, 4.5, and 6) with soy lecithin as control, and were stored for six month

Induced polarization (IP) is an acknowledged method in ore exploration and can be applied to evaluate the metal content in dumps containing the residues of ore processing facilities. Existing models explain the relationships between ore content and grain size of the ore particles with IP parameters. However, the models assume full water saturation of the ore containing samples, which is often not